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Author Details

Richard A Scheltema
Utrecht Institute for Pharmaceutical Sciences, Utrecht University
2008
57
31
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36690744Towards a structurally resolved human protein interaction network.Nat Struct Mol Biol2023
37646531Combination of deep XLMS with deep learning reveals an ordered rearrangement and assembly of a major protein component of the vaccinia virion.mBio2023
36697828Visualization of translation and protein biogenesis at the ER membrane.Nature2023
36549589Oxonium Ion-Guided Optimization of Ion Mobility-Assisted Glycoproteomics on the timsTOF Pro.Mol Cell Proteomics2023
36854377MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex.Open Biol2023
35063097Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology.Mol Cell2022
34191293Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.EMBO J2021
33711480Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry.Mol Cell Proteomics2021
34388369Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage.Mol Cell2021
34301900Notch-Jagged signaling complex defined by an interaction mosaic.Proc Natl Acad Sci U S A2021
34255029The assessment of Pseudomonas aeruginosa lectin LecA binding characteristics of divalent galactosides using multiple techniques.Glycobiology2021
32170184How paired PSII-LHCII supercomplexes mediate the stacking of plant thylakoid membranes unveiled by structural mass-spectrometry.Nat Commun2020
32031400To Cleave or Not To Cleave in XL-MS?J Am Soc Mass Spectrom2020
31924745Missing regions within the molecular architecture of human fibrin clots structurally resolved by XL-MS and integrative structural modeling.Proc Natl Acad Sci U S A2020
33065067Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry.Structure2020
32694122Benefits of Collisional Cross Section Assisted Precursor Selection (caps-PASEF) for Cross-linking Mass Spectrometry.Mol Cell Proteomics2020
32359834Structural Proteomics Applied to Plant Membrane Protein Complexes.Trends Plant Sci2020
30575379Cross-ID: Analysis and Visualization of Complex XL-MS-Driven Protein Interaction Networks.J Proteome Res2019
31572778PhoX: An IMAC-Enrichable Cross-Linking Reagent.ACS Cent Sci2019
31045356First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.Anal Chem2019
30740542Life history shapes variation in egg composition in the blue tit Cyanistes caeruleus.Commun Biol2019
30446747Efficient and robust proteome-wide approaches for cross-linking mass spectrometry.Nat Protoc2018
30021884Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.Mol Cell Proteomics2018
30021165Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca<sup>2+</sup>/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites.Cell Rep2018
27503676Arginine (Di)methylated Human Leukocyte Antigen Class I Peptides Are Favorably Presented by HLA-B*07.J Proteome Res2017
28111955Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)<sub>n</sub> and (X)<sub>n</sub>K/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics.J Proteome Res2017
28152593Combining Deep Sequencing, Proteomics, Phosphoproteomics, and Functional Screens To Discover Novel Regulators of Sphingolipid Homeostasis.J Proteome Res2017
28611213Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.Proc Natl Acad Sci U S A2017
28869719Phosphate Transfer in Activated Protein Complexes Reveals Interaction Sites.Angew Chem Int Ed Engl2017
28524877Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.Nat Commun2017
26760441Implementation of Ultraviolet Photodissociation on a Benchtop Q Exactive Mass Spectrometer and Its Application to Phosphoproteomics.Anal Chem2016
27480281Symmetry of Charge Partitioning in Collisional and UV Photon-Induced Dissociation of Protein Assemblies.J Am Chem Soc2016
27504491Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System.ACS Cent Sci2016
25887394A Double-Barrel Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) System to Quantify 96 Interactomes per Day.Mol Cell Proteomics2015
26174933Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair.Mol Syst Biol2015
24760958qcML: an exchange format for quality control metrics from mass spectrometry experiments.Mol Cell Proteomics2014
25280103Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4.Mol Cell2014
25360005The Q Exactive HF, a Benchtop mass spectrometer with a pre-filter, high-performance quadrupole and an ultra-high-field Orbitrap analyzer.Mol Cell Proteomics2014
23620052Direct proteomic quantification of the secretome of activated immune cells.Science2013
23611042High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome.J Proteome Res2013
22171319A framework for intelligent data acquisition and real-time database searching for shotgun proteomics.Mol Cell Proteomics2012
22515319SprayQc: a real-time LC-MS/MS quality monitoring system to maximize uptime using off the shelf components.J Proteome Res2012
21254760Andromeda: a peptide search engine integrated into the MaxQuant environment.J Proteome Res2011
21649496Richard A Scheltema.Bioanalysis2011
21401061PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis.Anal Chem2011
20109253The potential of metabolomics for Leishmania research in the post-genomics era.Parasitology2010
21152055Metabolomics to unveil and understand phenotypic diversity between pathogen populations.PLoS Negl Trop Dis2010
20824428Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis.Anal Bioanal Chem2010
20526351Use of reconstituted metabolic networks to assist in metabolomic data visualization and mining.Metabolomics2010
20645205Two time-point assessment of bile acid kinetics in humans using stable isotopes.Isotopes Environ Health Stud2010
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Collaborators

Utrecht University
Co-authored papers 22
Max-Planck Institute of Biochemistry
Co-authored papers 9
Max-Planck Institute of Biochemistry
Co-authored papers 5
ETH Zurich
Co-authored papers 3
University of California (Davis)
Co-authored papers 3
IMP-Institute of Molecular Pathology
Co-authored papers 3
McGill University
Co-authored papers 2
University of Groningen, University Medical Center Groningen
Co-authored papers 2
Institute of Chemistry, University of Campinas
Co-authored papers 2
Institute of Systems, University of Liverpool
Co-authored papers 2
University of Antwerp, University of Leeds
Co-authored papers 2
National Institute of Biological Sciences
Co-authored papers 2
Bruker Daltonics GmbH & Co. KG
Co-authored papers 2
Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University
Co-authored papers 2
University of Calgary, 0 Hospital Drive NW
Co-authored papers 2
University of California Irvine
Co-authored papers 2
University of Konstanz Universitatsstrasse 10
Co-authored papers 2
Institute for Systems Biology
Co-authored papers 2
Co-authored papers 2
Max Planck Institute for Developmental Biology
Co-authored papers 2
Institute of Life Sciences, The Hebrew University
Co-authored papers 2
Institute of Microbiology of the CAS
Co-authored papers 2
Institute for Biotechnology, Technical University Berlin
Co-authored papers 2
Center for Structural Mass Spectrometry, Martin Luther University Halle-Wittenberg
Co-authored papers 2
EMBL-European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Institute for Systems Biology
Co-authored papers 2
Johannes Gutenberg University Mainz
Co-authored papers 2
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
and Pharmacy, Freie Universitat Berlin
Co-authored papers 2
The Weizmann Institute of Science
Co-authored papers 1