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Author Details

Robert B Innis
National Institute of Mental Health
1978
394
90
PMIDPaper TitleJournal TitlePublished Year
37744469The Past, Present, and Future of the Brain Imaging Data Structure (BIDS).ArXiv2024
37017827Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (<sup>11</sup>C-NR2B-Me enantiomers) have high binding in cerebellum but not to Ͽ1 receptors.EJNMMI Res2023
37734962PET reporter systems for the brain.Trends Neurosci2023
35798558Whole-Body PET Imaging in Humans Shows That <sup>11</sup>C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs.J Nucl Med2023
37249618In vivo evaluation of a novel <sup>18</sup>F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.Eur J Nucl Med Mol Imaging2023
37082755Discovery of a High-Affinity Fluoromethyl Analog of [<sup>11</sup>C]5-Cyano-<i>N</i>-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide ([<sup>11</sup>C]CPPC) and Their Comparison in Mouse and Monkey as Colony-Stimulating Factor 1 Receptor Positron Emission Tomography Radioligands.ACS Pharmacol Transl Sci2023
34837109<sup>18</sup>F-GE180, a failed tracer for translocator protein, has no place in child abuse imaging.Pediatr Radiol2022
35772961First-in-Human Evaluation of <sup>18</sup>F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.J Nucl Med2022
35649646Cyclooxygenases as Potential PET Imaging Biomarkers to Explore Neuroinflammation in Dementia.J Nucl Med2022
35209743Comparison of three novel radiotracers for GluN2B-containing NMDA receptors in non-human primates: (R)-[[11]C]NR2B-Me, (R)-[[18]F]of-Me-NB1, and (S)-[[18]F]of-NB1.J Cereb Blood Flow Metab2022
35027372In Vivo Evaluation of 6 Analogs of <sup>11</sup>C-ER176 as Candidate <sup>18</sup>F-Labeled Radioligands for 18-kDa Translocator Protein.J Nucl Med2022
35236846PET-BIDS, an extension to the brain imaging data structure for positron emission tomography.Sci Data2022
32978284Repurposing <sup>11</sup>C-PS13 for PET Imaging of Cyclooxygenase-1 in Ovarian Cancer Xenograft Mouse Models.J Nucl Med2021
33796956Region- and voxel-based quantification in human brain of [<sup>18</sup>F]LSN3316612, a radioligand for O-GlcNAcase.EJNMMI Res2021
33853405[<sup>11</sup>C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain.J Cereb Blood Flow Metab2021
33491441Synthesis of [<sup>18</sup>F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey.ACS Chem Neurosci2021
34756026Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising <sup>18</sup>F-Labeled Ligand.J Med Chem2021
34151207Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB<sub>1</sub>R) Antagonist.ACS Pharmacol Transl Sci2021
33950298In vitro and pilot in vivo imaging of 18 kDa translocator protein (TSPO) in inflammatory vascular disease.EJNMMI Res2021
33310737<sup>11</sup>C Dosimetry Scans Should Be Abandoned.J Nucl Med2021
32399622First-in-human evaluation of [<sup>11</sup>C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain.Eur J Nucl Med Mol Imaging2020
31924728Evaluation of <sup>11</sup>C-NR2B-SMe and Its Enantiomers as PET Radioligands for Imaging the NR2B Subunit Within the NMDA Receptor Complex in Rats.J Nucl Med2020
32065076Guidelines for the content and format of PET brain data in publications and archives: A consensus paper.J Cereb Blood Flow Metab2020
33060616Development of a non-radiometric method for measuring the arterial input function of a <sup>11</sup>C-labeled PET radiotracer.Sci Rep2020
33098803PET imaging of neuroinflammation in neurological disorders.Lancet Neurol2020
33098761Neuroinflammation in psychiatric disorders: PET imaging and promising new targets.Lancet Psychiatry2020
32284396PET Imaging of Phosphodiesterase-4 Identifies Affected Dysplastic Bone in McCune-Albright Syndrome, a Genetic Mosaic Disorder.J Nucl Med2020
32212718Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D.ACS Chem Neurosci2020
32359360PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study.J Neuroinflammation2020
32404505PET ligands [<sup>18</sup>F]LSN3316612 and [<sup>11</sup>C]LSN3316612 quantify <i>O</i>-linked-β-<i>N</i>-acetyl-glucosamine hydrolase in the brain.Sci Transl Med2020
29430995[<sup>11</sup>C](<i>R</i>)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live <i>Disc1</i> locus-impaired mice.J Cereb Blood Flow Metab2019
30213846Evaluation of a PET Radioligand to Image <i>O</i>-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse.J Nucl Med2019
31353865Neuroinflammation in frontotemporal lobar degeneration revealed by <sup>11</sup> C-PBR28 PET.Ann Clin Transl Neurol2019
30811975Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT<sub>1B</sub> receptors.Nucl Med Biol2019
30655330Automatic Extraction of a Reference Region for the Noninvasive Quantification of Translocator Protein in Brain Using <sup>11</sup>C-PBR28.J Nucl Med2019
29749279Building a database for brain 18 kDa translocator protein imaged using [<sup>11</sup>C]PBR28 in healthy subjects.J Cereb Blood Flow Metab2019
29232493[Carboxyl-<sup>11</sup> C]Labelling of Four High-Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography.ChemMedChem2018
29971587PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects.EJNMMI Res2018
29959215Evaluation of Two Potent and Selective PET Radioligands to Image COX-1 and COX-2 in Rhesus Monkeys.J Nucl Med2018
30121138Decreased Cannabinoid CB<sub>1</sub> Receptors in Male Tobacco Smokers Examined With Positron Emission Tomography.Biol Psychiatry2018
30030837The expression of inflammatory markers and their potential influence on efflux transporters in drug-resistant mesial temporal lobe epilepsy tissue.Epilepsia2018
304001422-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET-Synthesis, Triage, and Radiolabeling.Molecules2018
30360553[<i>O</i>-<i>methyl</i>-<sup>11</sup>C]<i>N</i>-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1<i>H</i>-indole-2-carboxamide ([<sup>11</sup>C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging of Brain Dâ¿¿ Receptors in Rodents and Monkey.Molecules2018
28322082<sup>11</sup>C-DPA-713 has much greater specific binding to translocator protein 18â¿¿kDa (TSPO) in human brain than <sup>11</sup>C-( R)-PK11195.J Cereb Blood Flow Metab2018
29777199Influence of alcoholism and cholesterol on TSPO binding in brain: PET [<sup>11</sup>C]PBR28 studies in humans and rodents.Neuropsychopharmacology2018
29413519Imaging Translocator Protein as a Biomarker of Neuroinflammation in Dementia.Adv Pharmacol2018
297920353-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [<sup>11</sup>C]PS13 for Quantitative Imaging.ACS Chem Neurosci2018
296781053-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 1: Synthesis and Pharmacology.ACS Chem Neurosci2018
27488911An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter.J Cereb Blood Flow Metab2017
28179461<sup>11</sup>C-PBR28 PET detects translocator protein in a patient with astrocytoma and Alzheimer disease.Neurology2017
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Collaborators

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Co-authored papers 31
Co-authored papers 14
Yale University
Co-authored papers 7
McMaster University
Co-authored papers 7
Wake Forest University School of Medicine
Co-authored papers 6
UT Houston Medical School
Co-authored papers 5
Co-authored papers 5
Karolinska Institute
Co-authored papers 4
Georgetown University
Co-authored papers 4
Cancer Center Amsterdam, Vrije Universiteit Amsterdam
Co-authored papers 3
Lieber Institute for Brain Development (LIBD)
Co-authored papers 3
Brain Research Institute, University of California at Los Angeles
Co-authored papers 3
National Institute of Mental Health, National Institutes of Health
Co-authored papers 3
Max Planck Institute for Human Development
Co-authored papers 3
National Institute of Mental Health
Co-authored papers 3
University of Copenhagen
Co-authored papers 3
Big Data Science Institute, University of Oxford
Co-authored papers 2
Neuroscience Institute, Renaissance School of Medicine, Stony Brook University
Co-authored papers 2
Stanford University
Co-authored papers 2
Co-authored papers 2
The Australian e-Health Research Centre
Co-authored papers 2
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Stanford University
Co-authored papers 2
Neurobiology Research Unit, Copenhagen University Hospital
Co-authored papers 2
University of Arkansas School of Medicine
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
Donders Institute for Brain, Radboud University Nijmegen
Co-authored papers 2
Instituto Cajal
Co-authored papers 2
McGill University
Co-authored papers 2
Institut du Cerveau - Paris Brain Institute
Co-authored papers 2