Author details

Full Name

Jacqueline A Wilce

Affiliation

ORCID

Career Start Year

1995

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37668975	Using Surface Plasmon Resonance to Study SH2 Domain-Peptide Interactions.		2023
35924852	Genistein Targets STING-Driven Antiviral Responses.	mBio	2022
35911965	Regulation of TIA-1 Condensates: Zn and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation.	Frontiers in Molecular Biosciences	2022
35625882	Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability.	Biomedicines	2022
33621982	Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1.	Nucleic Acids Research	2021
32556302	Structure of the PCBP2/stem-loop IV complex underlying translation initiation mediated by the poliovirus type I IRES.	Nucleic Acids Research	2020
32079204	Direct Interaction between Calmodulin and the Grb7 RA-PH Domain.	International Journal of Molecular Sciences	2020
32360748	Partners of wild type Grb7 and a mutant lacking its calmodulin-binding domain.	Archives of Biochemistry and Biophysics	2020
32178593	Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26.	Emerging Microbes and Infections	2020
32768454	Detailed protocol for optimised expression and purification of functional monomeric human Heat Shock Factor 1.	Protein Expression and Purification	2020
32569368	Engineering the Ovarian Hormones Inhibin A and Inhibin B to Enhance Synthesis and Activity.	Endocrinology	2020
31479821	TDP-43 and FUS-structural insights into RNA recognition and self-association.	Current Opinion in Structural Biology	2019
31627265	Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity.	Molecules	2019
29346611	Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis.	Nucleic Acids Research	2018
30575518	The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in <i>C</i>. e<i>legans</i>.	Elife	2018
28184449	TIA-1 RRM23 binding and recognition of target oligonucleotides.	Nucleic Acids Res	2017
29018805	Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target.	Frontiers in Molecular Biosciences	2017
28467905	Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis.	Cell Rep	2017
29083893	Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.	Journal of Medicinal Chemistry	2017
29152602	Shortened Penetratin Cell-Penetrating Peptide Is Insufficient for Cytosolic Delivery of a Grb7 Targeting Peptide.	ACS Omega	2017
27257138	Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.	Scientific Reports	2016
27163492	The impact of cell-penetrating peptides on membrane bilayer structure during binding and insertion.		2016
26177105	Cooperative interplay of let-7 mimic and HuR with MYC RNA.	Cell Cycle	2015
26359549	Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.	Journal of Medicinal Chemistry	2015
24824036	The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain.	RNA Biol	2014
25522169	RNA recognition and stress granule formation by TIA proteins.	International Journal of Molecular Sciences	2014
24464577	Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines.	Breast Cancer Research and Treatment	2014
24637751	Preparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist.	Acta Crystallographica Section F:Structural Biology Communications	2014
23325848	Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.	Nucleic Acids Research	2013
23978401	Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR.	Cellular Signalling	2013
23935508	RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility.	PLoS Genetics	2013
23784963	Supramolecular self-assembly of N-acetyl-capped Î²-peptides leads to nano- to macroscale fiber formation.	Angewandte Chemie - International Edition	2013
23603827	Distinct binding properties of TIAR RRMs and linker region.	RNA Biol	2013
23355456	The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents.	ChemMedChem	2013
23592783	A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4.	J Biol Chem	2013
23559560	Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic target.	Protein Science	2013
23505041	Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?	Biopolymers	2013
22252416	Conformational stability studies of a stapled hexa-Î²3-peptide library.	Organic and Biomolecular Chemistry	2012
22344691	Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides.	Nucleic Acids Res	2012
22368252	Sequence requirements for RNA binding by HuR and AUF1.	Journal of Biochemistry	2012
22949113	Oligonucleotide binding proteins: the occurrence of dimer and multimer formation.	Advances in Experimental Medicine and Biology	2012
22213451	Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity.	Journal of Molecular Recognition	2012
22102042	Mutation and crystallization of the first KH domain of human polycytosine-binding protein 1 (PCBP1) in complex with DNA.		2011
21233170	Different modes of interaction by TIAR and HuR with target RNA and DNA.	Nucleic Acids Res	2011
21134757	Benzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists.	Bioorganic and Medicinal Chemistry	2011
20564009	Uptake of a cell permeable G7-18NATE contruct into cells and binding with the Grb-7-SH2 domain.	Biopolymers	2011
21802427	Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression.	Journal of Molecular Biology	2011
20212169	Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition.	Proc Natl Acad Sci U S A	2010
21139214	Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide.		2010
19719157	Synthesis of stapled beta3-peptides through ring-closing metathesis.	Organic Letters	2009