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Author Details

William H Klein
Columbia University
1972
144
57
PMIDPaper TitleJournal TitlePublished Year
33914865Ret signaling in ureteric bud epithelial cells controls cell movements, cell clustering and bud formation.Development2021
30995485Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.Cell Rep2019
31619788Regulation of lifespan by neural excitation and REST.Nature2019
30333037Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.Mol Neurodegener2018
28356311Regulation of <i>Brn3b</i> by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina.Development2017
26962139Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development.Proc Biol Sci2016
25953241Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells.Nat Commun2015
24799426Transcriptome of Atoh7 retinal progenitor cells identifies new Atoh7-dependent regulatory genes for retinal ganglion cell formation.Dev Neurobiol2014
23142158Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene.Exp Eye Res2013
24082127The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse.Proc Natl Acad Sci U S A2013
23651855The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo.Genes Dev2013
23515314Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity.J Biol Chem2013
23293286Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7.Development2013
22326227Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.Dev Biol2012
23170059Adult mice transplanted with embryonic retinal progenitor cells: new approach for repairing damaged optic nerves.Mol Vis2012
22745484Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb.J Neurosci2012
20951721Overlapping spatiotemporal patterns of regulatory gene expression are required for neuronal progenitors to specify retinal ganglion cell fate.Vision Res2011
21800307Neurosensory and neuromuscular organization in tube feet of the sea urchin Strongylocentrotus purpuratus.J Comp Neurol2011
21264243Myogenin regulates exercise capacity but is dispensable for skeletal muscle regeneration in adult mdx mice.PLoS One2011
20969844Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development.Dev Biol2011
20887891Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.Cell2010
21042574Myogenin regulates exercise capacity and skeletal muscle metabolism in the adult mouse.PLoS One2010
20713522Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons.Genes Dev2010
19109424A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression.Mol Biol Cell2009
21798176Intragenomic evolution of a transcriptional enhancer in the genome of Strongylocentrotus purpuratus.Mar Genomics2009
19368800Respecification of ectoderm and altered Nodal expression in sea urchin embryos after cobalt and nickel treatment.Mech Dev2009
19459208Epitope-tagging Math5 and Pou4f2: new tools to study retinal ganglion cell development in the mouse.Dev Dyn2009
19517573Reduced O2 and elevated ROS in sea urchin embryos leads to defects in ectoderm differentiation.Dev Dyn2009
19109949Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice.Exp Eye Res2009
18077589Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse.Development2008
18787067Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5.Development2008
18721801Myogenin regulates a distinct genetic program in adult muscle stem cells.Dev Biol2008
18836459The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.Nat Med2008
18940588Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex.Neuron2008
18460603Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2.Proc Natl Acad Sci U S A2008
17519332Canonical Wnt signaling functions in second heart field to promote right ventricular growth.Proc Natl Acad Sci U S A2007
17904117Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle.Dev Biol2007
17638088Smooth muscle persists in the muscularis externa of developing and adult mouse esophagus.J Muscle Res Cell Motil2007
17629466Compensational regulation of bHLH transcription factors in the postnatal development of BETA2/NeuroD1-null retina.Mech Dev2007
17710433SpGataE, a Strongylocentrotus purpuratus ortholog of mammalian Gata4/5/6: protein expression, interaction with putative target gene spec2a, and identification of friend of Gata factor SpFog1.Dev Genes Evol2007
16407395Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size.Development2006
17095691The genome of the sea urchin Strongylocentrotus purpuratus.Science2006
16965768A genomic view of the sea urchin nervous system.Dev Biol2006
16959241Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development.Dev Biol2006
15797020Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina.Curr Biol2005
15882586A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate.Dev Biol2005
15882584Strongylocentrotus purpuratus transcription factor GATA-E binds to and represses transcription at an Otx-Goosecoid cis-regulatory element within the aboral ectoderm-specific spec2a enhancer.Dev Biol2005
15871032Structure, expression, and transcriptional regulation of the Strongylocentrotus franciscanus spec gene family encoding intracellular calcium-binding proteins.Dev Genes Evol2005
15733064Identification of an N-terminal transcriptional activation domain within Brn3b/POU4f2.Differentiation2005
15036214A gene regulatory hierarchy for retinal ganglion cell specification and differentiation.Semin Cell Dev Biol2004
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Collaborators

University at Buffalo, State University of New York
Co-authored papers 20
Co-authored papers 16
University of Texas Health Science Center at Houston Medical School
Co-authored papers 12
University of Miami
Co-authored papers 11
California Institute of Technology
Co-authored papers 10
The University of Texas M. D. Anderson Cancer Center
Co-authored papers 9
University Drive Simon Fraser University
Co-authored papers 9
National Institute of Dental and Craniofacial Research, National Institutes of Health
Co-authored papers 8
Brown University
Co-authored papers 6
Sabanci University
Co-authored papers 6
National Institute of Dental and Craniofacial Research, National Institutes of Health
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth
Co-authored papers 4
Co-authored papers 3
National Institute of Child Health and Human Development
Co-authored papers 2
Shimoda Marine Research Center, University of Tsukuba
Co-authored papers 2
Singapore General Hospital
Co-authored papers 2
University of Victoria
Co-authored papers 2
Umea University
Co-authored papers 2
University of Victoria
Co-authored papers 2
Duke University
Co-authored papers 2
University of Gothenburg
Co-authored papers 2
Queen Mary University of London
Co-authored papers 2
Department of Biology and Environmental Science University of Gothenburg
Co-authored papers 2
University of Victoria
Co-authored papers 2
Western Regional Research Center
Co-authored papers 2
Center for Coregulator Research, Baylor College of Medicine
Co-authored papers 2
Arizona State University
Co-authored papers 2
Uppsala University
Co-authored papers 2
Uppsala University
Co-authored papers 2