Skip to Main Content

Author Details

Lori L Bonnycastle
1992
97
63
PMIDPaper TitleJournal TitlePublished Year
37386251Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis.Nat Genet2023
37603758Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.Proc Natl Acad Sci U S A2023
37961277Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.bioRxiv2023
37858332Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells.Cell Metab2023
37214922Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.bioRxiv2023
37333221Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours.bioRxiv2023
36757889Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.Proc Natl Acad Sci U S A2023
36055244Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.Am J Hum Genet2022
35589964ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.Int J Obes (Lond)2022
34081913SARS-CoV-2 infection induces beta cell transdifferentiation.Cell Metab2021
34108472Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.Nat Commun2021
33727701Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2021
34038741Genetic effects on liver chromatin accessibility identify disease regulatory variants.Am J Hum Genet2021
33230300Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2020
31984226Single-cell transcriptomics from human pancreatic islets: sample preparation matters.Biol Methods Protoc2020
32817962ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition.medRxiv2020
31064750Hydroa vacciniforme-like lymphoproliferative disorder: an EBV disease with a low risk of systemic illness in whites.Blood2019
31118516Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.Nature2019
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
28146470Rare and low-frequency coding variants alter human adult height.Nature2017
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
28448500Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.PLoS Genet2017
28443625Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.Nat Commun2017
28832619Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.PLoS Genet2017
28566273An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Diabetes2017
29030403New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475â¿¿000 Individuals.Circ Cardiovasc Genet2017
29257133Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2017
28193859Genetic regulatory signatures underlying islet gene expression and type 2 diabetes.Proc Natl Acad Sci U S A2017
27876822A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.Nat Commun2016
27355579Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.PLoS Genet2016
27398621The genetic architecture of type 2 diabetes.Nature2016
27353450The genetic regulatory signature of type 2 diabetes in human skeletal muscle.Nat Commun2016
27618452The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Nat Genet2016
27618447Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.Nat Genet2016
26426971The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.PLoS Genet2015
25673413Genetic studies of body mass index yield new insights for obesity biology.Nature2015
26551672Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Nat Genet2015
24509480Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.Nat Genet2014
24296717Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.Diabetes2014
24497850Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci.PLoS Genet2014
23555291Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.PLoS Genet2013
23903355Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation.Diabetes2013
23754948Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.PLoS Genet2013
24097068Discovery and refinement of loci associated with lipid levels.Nat Genet2013
24097064Common variants associated with plasma triglycerides and risk for coronary artery disease.Nat Genet2013
23563607Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.Nat Genet2013
23314155Use of microarray hybrid capture and next-generation sequencing to identify the anatomy of a transgene.Nucleic Acids Res2013
23557707Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.Diabetes2013
22238593A genome-wide association search for type 2 diabetes genes in African Americans.PLoS One2012
22553379Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men.Diabetes2012
  • 1 - 50 of 97

Recommended Authors

Collaborators

University of Michigan ann arbor
Co-authored papers 81
Co-authored papers 73
Co-authored papers 66
Co-authored papers 61
Co-authored papers 61
Co-authored papers 60
Co-authored papers 56
Co-authored papers 54
Co-authored papers 53
Co-authored papers 52
Co-authored papers 47
Co-authored papers 47
Co-authored papers 45
Co-authored papers 44
Co-authored papers 42
Co-authored papers 41
Co-authored papers 41
Regeneron Pharmaceuticals Inc.
Co-authored papers 41
Co-authored papers 40
Co-authored papers 39
Co-authored papers 37
Baylor College of Medicine
Co-authored papers 36
Co-authored papers 36
Center for Precision Health Research, National Human Genome Research Institute
Co-authored papers 35
Co-authored papers 35
Co-authored papers 34
Stanford University School of Medicine
Co-authored papers 34
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 33
German Research Center for Cardiovascular Disease (DZHK)
Co-authored papers 33
King's College London
Co-authored papers 33