Author details

Full Name

Sujatha Venkataraman

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38039965	A road map for the treatment of pediatric diffuse midline glioma.	Cancer Cell	2024
36915612	The PARP inhibitor Rucaparib synergizes with radiation to attenuate atypical teratoid rhabdoid tumor growth.	Neurooncol Adv	2023
37160547	Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data.	Curr Oncol Rep	2023
36747867	Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy.	bioRxiv	2023
37114557	Targeting B7â¿¿H3 through EZH2 inhibition in MYCâ¿¿positive Group 3 medulloblastoma.	Oncol Rep	2023
37486991	EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.	Neuro Oncol	2023
35344040	Venetoclax Cooperates with Ionizing Radiation to Attenuate Diffuse Midline Glioma Tumor Growth.	Clin Cancer Res	2022
35406445	SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma.	Cancers (Basel)	2022
34077540	Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.	Neuro Oncol	2022
35179215	Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors.	Int J Oncol	2022
35143643	Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels.	Blood	2022
34477871	A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.	Neuro Oncol	2022
34545084	Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.	Nat Commun	2021
33910002	Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma.	Cell Rep	2021
33749791	NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.	J Neuropathol Exp Neurol	2021
33494392	A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma.	Cancers (Basel)	2021
32783945	Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.	Cell Rep	2020
32268092	Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.	Cell Rep	2020
31969682	Correction: BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.	Oncogene	2020
31594826	Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-ÎºB Pathway in Preclinical Models of Pediatric High-Grade Glioma.	Mol Cancer Ther	2020
32195191	Increased HDAC Activity and c-MYC Expression Mediate Acquired Resistance to WEE1 Inhibition in Acute Leukemia.	Front Oncol	2020
31844250	BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.	Oncogene	2020
32180106	Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine.	J Neurooncol	2020
32642682	Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine.	Neurooncol Adv	2020
33086074	Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.	Cell Rep	2020
32567728	The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.	Mol Carcinog	2020
31382461	Role of MYC-miR-29-B7-H3 in Medulloblastoma Growth and Angiogenesis.	J Clin Med	2019
30230537	Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.	Int J Cancer	2019
30626740	Combined functional genomic and chemical screens identify SETD8 as a therapeutic target in MYC-driven medulloblastoma.	JCI Insight	2019
30899360	Therapeutic targeting of immune checkpoints with small molecule inhibitors.	Am J Transl Res	2019
29207163	Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.	Oncol Rep	2018
29568403	Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer.	Oncotarget	2018
29228610	Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.	Oncotarget	2017
28510691	NF-ÎºB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.	Neuro Oncol	2017
28655785	A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.	Mol Cancer Ther	2017
28360821	Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma.	Cancer Cell Int	2017
27538997	Polo-like KinaseÂ 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.	BMC Cancer	2016
27304454	A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.	ACS Chem Biol	2016
26745241	A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.	ACS Chem Biol	2016
27233998	Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension.	Am J Physiol Lung Cell Mol Physiol	2016
26944191	MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene.	Free Radical Biology and Medicine	2016
27449089	Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.	Oncotarget	2016
27633003	MPS1 kinase as a potential therapeutic target in medulloblastoma.	Oncol Rep	2016
24796395	Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.	Oncotarget	2014
24661910	Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.	Mol Cancer	2014
23212916	MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.	J Biol Chem	2013
23190500	Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.	Neuro Oncol	2013
23138228	Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.	J Neurooncol	2013
22246202	Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells.	J Neurooncol	2012
22390279	Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.	BMC Cancer	2012