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Author Details

Mikael Sigvardsson
Lund University, Linkoping University. .
1993
146
47
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36861396B-lineage acute lymphoblastic leukemia causes cellautonomous defects in long-term hematopoietic stem cell function.Haematologica2023
37702745TGF-β Promotes the Postselection Thymic Development and Peripheral Function of IFN-γ-Producing Invariant NKT cells.J Immunol2023
37018663Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option.Blood2023
36405705Editorial: Molecular switches of the immune system: The E-protein/Id axis in hematopoietic development and function.Front Immunol2022
35584393Developmental cues license megakaryocyte priming in murine hematopoietic stem cells.Blood Adv2022
35371057Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in <i>E2a<sup>-/-</sup></i> T Acute Lymphoblastic Leukemia.Front Immunol2022
35830859IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage.Immunity2022
34021049B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors.J Immunol2021
33619557EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.Blood2021
33857289The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.J Exp Med2021
31296580Progression of progenitor B-cell leukemia is associated with alterations of the bone marrow micro-environment.Haematologica2020
32094206Ezh2 Represses Transcription of Innate Lymphoid Genes in B Lymphocyte Progenitors and Maintains the B-2 Cell Fate.J Immunol2020
32747500ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development.J Immunol2020
32719520The transcription factor BCL-6 controls early development of innate-like T cells.Nat Immunol2020
3238414913q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking.Blood2020
30962294Cutting Edge: Lymphomyeloid-Primed Progenitor Cell Fates Are Controlled by the Transcription Factor Tal1.J Immunol2019
31562190Lin28b controls a neonatal to adult switch in B cell positive selection.Sci Immunol2019
31381561PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia.PLoS Genet2019
29514790<i>Sipa1</i> deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm.Blood Adv2018
29945938Distinct roles of mesenchymal stem and progenitor cells during the development of acute myeloid leukemia in mice.Blood Adv2018
29915154Zinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment.Mol Cell Biol2018
29966360Molecular Regulation of Differentiation in Early B-Lymphocyte Development.Int J Mol Sci2018
29899037Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.J Exp Med2018
30171019Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1).Genome Res2018
29703840Transcription factor ID2 prevents E proteins from enforcing a naïve T lymphocyte gene program during NK cell development.Sci Immunol2018
29628141Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells.Cell2018
28572215Correction: Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in <i>LAT</i>.J Exp Med2017
28118066Cellular plasticity in B-cell leukemia.Cell Cycle2017
28490575EZH2 Regulates the Developmental Timing of Effectors of the Pre-Antigen Receptor Checkpoints.J Immunol2017
29192121Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors.EMBO J2017
29262527Regulatory T cells characterized by low Id3 expression are highly suppressive and accumulate during chronic infection.Oncotarget2017
26871596Exploring the multifaceted nature of the common lymphoid progenitor compartment.Curr Opin Immunol2016
26500141A novel Lin-CD34+CD38- integrin α2- bipotential megakaryocyte-erythrocyte progenitor population in the human bone marrow.Leukemia2016
27664237Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia.Genes Dev2016
27974197Id3 Maintains Foxp3 Expression in Regulatory T Cells by Controlling a Transcriptional Network of E47, Spi-B, and SOCS3.Cell Rep2016
27913602Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states.Genes Dev2016
27456481Identification of Stage-Specific Surface Markers in Early B Cell Development Provides Novel Tools for Identification of Progenitor Populations.J Immunol2016
27242165Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT.J Exp Med2016
27412884Type 1 Diabetes Mellitus Donor Mesenchymal Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro.Stem Cells Transl Med2016
27069114The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2.J Exp Med2016
25452561Splenic B cells from Hymenolepis diminuta-infected mice ameliorate colitis independent of T cells and via cooperation with macrophages.J Immunol2015
26056231Combined heterozygous loss of Ebf1 and Pax5 allows for T-lineage conversion of B cell progenitors.J Exp Med2015
26228168Wipping p53 into subservience in B-cell development.Blood2015
25838350Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.Blood2015
25990863Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia.Blood2015
23297135E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.Blood2013
24078629Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.J Biol Chem2013
24244015Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.J Immunol2013
23476050An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.Blood2013
23165626Expression of integrin α2 receptor in human cord blood CD34+CD38-CD90+ stem cells engrafting long-term in NOD/SCID-IL2Rγ(c) null mice.Stem Cells2013
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Collaborators

Robert M??nsson
Karolinska Institutet
Co-authored papers 27
Sasan Zandi
University of Toronto
Co-authored papers 13
Eva Welinder
University of California San Diego
Co-authored papers 7
James Hagman
National Jewish Health
Co-authored papers 6
Cornelis Murre
University of California
Co-authored papers 4
Sven Bilke
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
Christopher K Glass
University of California San Diego
Co-authored papers 3
Yin C Lin
Baylor Institute for Immunology Research
Co-authored papers 3
Christopher Benner
Michigan State University College of Human Medicine
Co-authored papers 3
Suchit Jhunjhunwala
Genentech Inc.
Co-authored papers 2
Rudolf Grosschedl
Co-authored papers 2
Malin Larsson
Co-authored papers 2
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 2
Anna Lasorella
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 2
Janusz Dutkowski
Data4Cure Inc.
Co-authored papers 2
Claus Nerlov
MRC Weatherall Institute of Molecular Medicine, University of Oxford
Co-authored papers 2
Michele K Anderson
Sunnybrook Research Institute, University of Toronto
Co-authored papers 2
Elinore M Mercer
University of California
Co-authored papers 2
Hans Clevers
Princess Maxima Center for Pediatric Oncology
Co-authored papers 1
Celso A Espinoza
Ludwig Institute for Cancer Research
Co-authored papers 1
Erik Larsson
Co-authored papers 1
Sven Heinz
U.C. San Diego School of Medicine
Co-authored papers 1
Maria Sunnerhagen
Linkoping University
Co-authored papers 1
Nabeel Bardeesy
Massachusetts General Hospital
Co-authored papers 1
Antonio Iavarone
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 1
Marsela Braunstein
Princess Margaret Cancer Centre
Co-authored papers 1
Evan D Rosen
Co-authored papers 1
Brian A Williams
Co-authored papers 1
Carl A K Borrebaeck
Lund University
Co-authored papers 1
David T Scadden
Co-authored papers 1
Release 1.2