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Author Details

Ali Shilatifard
Northwestern University Feinberg School of Medicine
1991
264
92
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36645269Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in OriLyt.Microbiol Spectr2023
37749225Iron drives anabolic metabolism through active histone demethylation and mTORC1.Nat Cell Biol2023
37922911Transcriptional elongation control in developmental gene expression, aging, and disease.Mol Cell2023
37252797Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations.J Clin Invest2023
37452018Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis.Nat Commun2023
37083523Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription.Sci Adv2023
37442129Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation.Mol Cell2023
37406132The power of altruism in academic science.Sci Adv2023
36888719Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C.Sci Adv2023
35247919Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumors.Mol Cancer Ther2022
35353564On Healthy Scientific Debates.Sci Adv2022
35675412The dire need for federal support of molecular research, then and now.Sci Adv2022
35534714Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer.Nat Rev Mol Cell Biol2022
35500115A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells.Proc Natl Acad Sci U S A2022
35487209It's a DoG-eat-DoG world-altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production.Mol Cell2022
36476474PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing.Mol Cell2022
35973425SPT6 functions in transcriptional pause/release via PAF1C recruitment.Mol Cell2022
36197977CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS.Sci Adv2022
36197969Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma.Sci Adv2022
36260687Editorial retraction.Sci Adv2022
32958894COMPASS and SWI/SNF complexes in development and disease.Nat Rev Genet2021
33883147Building on a strong foundation.Sci Adv2021
33621212Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment.JCI Insight2021
33593726Editorial expression of concern.Sci Adv2021
33731453Epigenetic reprogramming of host and viral genes by Human Cytomegalovirus infection in Kasumi-3 myeloid progenitor cells at early times post-infection.J Virol2021
33589837Decoding the protein composition of whole nucleosomes with Nuc-MS.Nat Methods2021
33723438The roles of Polycomb repressive complexes in mammalian development and cancer.Nat Rev Mol Cell Biol2021
35122023Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia.Nat Cancer2021
34407935Expanding the breadth and depth of <i>Science Advances</i>.Sci Adv2021
34819353A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer.Genes Dev2021
34759321Dietary palmitic acid promotes a prometastatic memory via Schwann cells.Nature2021
34433651TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas.Clin Cancer Res2021
34786730UBR7 acts as a histone chaperone for post-nucleosomal histone H3.EMBO J2021
34730992Integrator enforces the fidelity of transcriptional termination at protein-coding genes.Sci Adv2021
34426512A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells.Genome Res2021
34480849SPT5 stabilization of promoter-proximal RNA polymerase II.Mol Cell2021
34078608Epigenomic landscape and 3D genome structure in pediatric high-grade glioma.Sci Adv2021
33446572Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression.Genes Dev2021
33471107Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma.Neuro Oncol2021
32393859Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.Nat Genet2020
31965984The role of histone modifications in leukemogenesis.J Biosci2020
31724694A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS.Nucleic Acids Res2020
32064518A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress.Nucleic Acids Res2020
33287886Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells.Acta Neuropathol Commun2020
33257899Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation.Nat Genet2020
33257409Lung transplantation for patients with severe COVID-19.Sci Transl Med2020
33033055A small UTX stabilization domain of Trr is conserved within mammalian MLL3-4/COMPASS and is sufficient to rescue loss of viability in null animals.Genes Dev2020
33140069Lung transplantation for pulmonary fibrosis secondary to severe COVID-19.medRxiv2020
33077595DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.Proc Natl Acad Sci U S A2020
32637595Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family.Sci Adv2020
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Collaborators

Jessica Schneider
Saint Louis University School of Medicine
Co-authored papers 15
Adam Wood
Saint Louis University School of Medicine
Co-authored papers 13
Mark Johnston
University of Colorado School of Medicine
Co-authored papers 9
Jim Dover
Saint Louis University School of Medicine
Co-authored papers 8
Rintaro Hashizume
Co-authored papers 8
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 8
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 8
Georgios Skiniotis
Stanford University School of Medicine
Co-authored papers 7
Amanda M Saratsis
Co-authored papers 7
Neil L Kelleher
Northwestern University
Co-authored papers 7
Shelley L Berger
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 7
Lihua Zou
Co-authored papers 6
Rishi R Lulla
Hasbro Children's Hospital, Brown University.
Co-authored papers 5
Craig Horbinski
Co-authored papers 5
Richard D Cummings
Co-authored papers 5
Stephanie E Kong
Cancer Research UK London Research Institute
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Michael S Kobor
University of British Columbia
Co-authored papers 4
Sue L Jaspersen
Stowers Institute for Medical Research
Co-authored papers 4
T Miller
Saint Louis University School of Medicine
Co-authored papers 4
Kimberly M Dean
Center for RNA Biology, University of Rochester School of Medicine and Dentistry
Co-authored papers 4
Danny Reinberg
HHMI/NYU Langone School of Medicine
Co-authored papers 3
Michael-Christopher Keogh
EpiCypher Inc.
Co-authored papers 3
Gerard Cagney
Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 3
Nitin R Wadhwani
Feinberg School of Medicine, Northwestern University
Co-authored papers 3
Charles D James
Co-authored papers 3
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 3
Ashkan Golshani
Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 3
Karl W Henry
The Wistar Institute
Co-authored papers 2
Kristin Ingvarsdottir
Epigenetics Institute, University of Pennsylvania
Co-authored papers 2
Brian D Slaughter
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Release 1.2