Author details

Full Name

Parmjit S Jat

Affiliation

UCL Institute of Prion Diseases

ORCID

Career Start Year

1981

Papers

100

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36535427	Prion Propagation is Dependent on Key Amino Acids in Charge Cluster 2 within the Prion Protein.	J Mol Biol	2023
37069149	Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma.	Signal Transduct Target Ther	2023
35158800	Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.	Cancers (Basel)	2022
35680944	A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody.	Sci Rep	2022
34728711	Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.	Sci Rep	2021
33855023	Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype.	Front Cell Dev Biol	2021
33610557	Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium.	J Mol Biol	2021
32949544	Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.	Lancet Neurol	2020
32944514	Isolation, purification, and conditional immortalization of murine glomerular endothelial cells of microvascular phenotype.	MethodsX	2020
32900920	Highly infectious prions are not directly neurotoxic.	Proc Natl Acad Sci U S A	2020
31519924	Generation of c-MycER<sup>TAM</sup>-transduced human late-adherent olfactory mucosa cells for potential regenerative applications.	Sci Rep	2019
27213811	Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15.	PLoS One	2016
26619948	Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer.	Int J Cancer	2016
25311251	Identification of clinical target areas in the brainstem of prion-infected mice.	Neuropathol Appl Neurobiol	2015
26631378	A systematic investigation of production of synthetic prions from recombinant prion protein.	Open Biol	2015
26172396	Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.	J Pathol	2015
24270410	The miR-106b~25 cluster promotes bypass of doxorubicin-induced senescence and increase in motility and invasion by targeting the E-cadherin transcriptional activator EP300.	Cell Death Differ	2014
25557529	Tumour suppressors and cellular senescence.	IUBMB Life	2014
25255445	Regulation of p53 and Rb links the alternative NF-ÎºB pathway to EZH2 expression and cell senescence.	PLoS Genet	2014
25278290	Identification of small proline-rich repeat protein 3 as a novel atheroprotective factor that promotes adaptive Akt signaling in vascular smooth muscle cells.	Arterioscler Thromb Vasc Biol	2014
24981831	Cellular senescence and aging: the role of B-MYB.	Aging Cell	2014
24833721	In vitro screen of prion disease susceptibility genes using the scrapie cell assay.	Hum Mol Genet	2014
24843046	Identification of a gene regulatory network associated with prion replication.	EMBO J	2014
23572577	Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients.	Proc Natl Acad Sci U S A	2013
24043947	Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence.	Onco Targets Ther	2013
23625514	Effects of CT-Xp gene knock down in melanoma cell lines.	Oncotarget	2013
23615505	The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation.	Kidney Int	2013
21242976	Activation of nuclear factor-kappa B signalling promotes cellular senescence.	Oncogene	2011
21990145	Deciphering the role of nuclear factor-ÎºB in cellular senescence.	Aging (Albany NY)	2011
21740549	An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence.	BMC Genomics	2011
21505437	Rapid cell-surface prion protein conversion revealed using a novel cell system.	Nat Commun	2011
19955187	Conditionally immortalized human podocyte cell lines established from urine.	Am J Physiol Renal Physiol	2010
21137025	Proteome profiling of immortalization-to-senescence transition of human breast epithelial cells identified MAP2K3 as a senescence-promoting protein which is downregulated in human breast cancer.	Proteomics Clin Appl	2010
20668098	Cell-cell contact regulates gene expression in CDK4-transformed mouse podocytes.	Am J Physiol Renal Physiol	2010
20642837	Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines.	Breast Cancer Res	2010
18922873	Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.	J Virol	2009
19615061	Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues.	BMC Genomics	2009
19737964	Decreased poly(ADP-ribosyl)ation of CTCF, a transcription factor, is associated with breast cancer phenotype and cell proliferation.	Clin Cancer Res	2009
18188180	A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding.	EMBO Rep	2008
17488820	Surveillance mechanism linking Bub1 loss to the p53 pathway.	Proc Natl Acad Sci U S A	2007
17600495	Preparation of monoclonal antibodies against the spindle checkpoint kinase Bub1.	Hybridoma (Larchmt)	2007
17283147	Ability to acquire drug resistance arises early during the tumorigenesis process.	Cancer Res	2007
16234270	Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway.	Am J Physiol Endocrinol Metab	2006
17005159	Retrovirus-mediated conditional immortalization and analysis of established cell lines of osteoclast precursor cells.	Biochem Biophys Res Commun	2006
17085477	ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.	Nucleic Acids Res	2006
17014703	Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.	Breast Cancer Res	2006
15574883	Transcriptional networks and cellular senescence in human mammary fibroblasts.	Mol Biol Cell	2005
14732683	Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1.	Proc Natl Acad Sci U S A	2004
15572682	Functional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survival.	Mol Cell Biol	2004
15188452	Order of genetic events is critical determinant of aberrations in chromosome count and structure.	Genes Chromosomes Cancer	2004

1 - 50 of 100

Vera Gorbunova

University of Rochester

Career Start Year 1997

Number of shared co-authors 0

Christian Beaus??jour

CHU Sainte-Justine Research Center

Career Start Year 1996

Number of shared co-authors 0

William Clark

Cancer Research UK Beatson Institute

Career Start Year 1993

Number of shared co-authors 0

Stephen Chung

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1993

Number of shared co-authors 0

Julien Sage

Department of Pediatrics Stanford University Stanford California USA.

Career Start Year 1993

Number of shared co-authors 0

James DeGregori

University of Colorado Anschutz Medical Campus

Career Start Year 1991

Number of shared co-authors 0

Peter D Adams

Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1991

Number of shared co-authors 0

Andrew Wakeham

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network

Career Start Year 1989

Number of shared co-authors 0

Daniel S Peeper

Netherlands Cancer Institute

Career Start Year 1987

Number of shared co-authors 0

William C Hahn

Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute

Career Start Year 1987

Number of shared co-authors 1

Claudio Schneider

Laboratorio Nazionale-Consorzio Interuniversitario per le Biotecnologie

Career Start Year 1987

Number of shared co-authors 1

Satyajit Ray

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1986

Number of shared co-authors 0

Siu-Pok Yee

University of Connecticut Health Center

Career Start Year 1981

Number of shared co-authors 0

Ze'ev Ronai

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1981

Number of shared co-authors 2

David J Adams

Wellcome Sanger Institute

Career Start Year 1980

Number of shared co-authors 8

David M Thomas

Garvan Institute of Medical Research

Career Start Year 1980

Number of shared co-authors 5

Michael C Ostrowski

Hollings Cancer Center, Medical University of South Carolina

Career Start Year 1979

Number of shared co-authors 0

Glenn Merlino

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1978

Number of shared co-authors 0

Martine F Roussel

St. Jude Children's Research Hospital

Career Start Year 1977

Number of shared co-authors 0

Lawrence A Donehower

Baylor College of Medicine

Career Start Year 1975

Number of shared co-authors 3

Bruce J Aronow

Cincinnati Children's Hospital Medical Center

Career Start Year 1975

Number of shared co-authors 2

Frank McCormick

Frederick National Laboratory for Cancer Research

Career Start Year 1975

Number of shared co-authors 1

Hartmut Land

University of Rochester Medical Center, Wilmot Cancer Institute

Career Start Year 1974

Number of shared co-authors 5

Owen N Witte

University of California los angeles

Career Start Year 1972

Number of shared co-authors 3

Tak W Mak

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1970

Number of shared co-authors 2

Charles J Sherr

St. Jude Children's Research Hospital

Career Start Year 1968

Number of shared co-authors 0

Tony Hunter

Salk Institute for Biological Studies

Career Start Year 1968

Number of shared co-authors 0

Arnold J Levine

Simons Center for Systems Biology, Institute for Advanced Study

Career Start Year 1967

Number of shared co-authors 1

J. Carl Barrett

Oncology R&D

Career Start Year 1966

Number of shared co-authors 2

Norman E Sharpless

National Cancer Institute

Career Start Year 1945

Number of shared co-authors 2

row(s) 1 - 30 of 30

Paris Ataliotis

Molecular and Clinical Sciences Research Institute, University of London

Co-authored papers 6

Sunil R Lakhani

University of Queensland

Co-authored papers 5

Andrew K Groves

Baylor College of Medicine

Co-authored papers 5

Mark Noble

University of Rochester Medical Center

Co-authored papers 5

Alan Mackay

Co-authored papers 4

Sebastian Brandner

UCL Queen Square Institute of Neurology

Co-authored papers 4

Otavia L Caballero

Ludwig Institute for Cancer Research Ltd.

Co-authored papers 3

Andrew J G Simpson

University of Hull

Co-authored papers 3

Peter T Simpson

UQ Centre for Clinical Research, The University of Queensland

Co-authored papers 3

Alan Entwistle

The Ludwig Institute for Cancer Research

Co-authored papers 3

Jeffrey B Kopp

National Institutes of Health, National Institute of Diabetes

Co-authored papers 2

Jean J Zhao

Co-authored papers 2

Leonard Da Silva

Pathology Queensland The Royal Brisbane and Women's Hospital Brisbane Qld Australia.

Co-authored papers 2

K Bevan

Co-authored papers 2

Susan C Barnett

University of Glasgow, University Place

Co-authored papers 2

Alan Ashworth

UCSF Helen Diller Family Comprehensive Cancer Center

Co-authored papers 2

Oliver B??gler

American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University

Co-authored papers 2

Damian R Wren

Frimley Health NHS Foundation Trust

Co-authored papers 1

Steven M Dubinett

David Geffen School of Medicine at university of california los angeles

Co-authored papers 1

Sean M Grimmond

The University of Melbourne

Co-authored papers 1

Chris Jones

Co-authored papers 1