Skip to Main Content

Author Details

Lawrence E Heisler
Ontario Institute for Cancer Research
1992
49
31
PMIDPaper TitleJournal TitlePublished Year
37874259Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA.Cancer Discov2024
36610996A polygenic two-hit hypothesis for prostate cancer.J Natl Cancer Inst2023
34737207Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with <i>Fusobacterium nucleatum</i> and Its Subspecies <i>animalis</i>.Cancer Epidemiol Biomarkers Prev2022
34824250The telomere length landscape of prostate cancer.Nat Commun2021
33592074Prospective observational study and serosurvey of SARS-CoV-2 infection in asymptomatic healthcare workers at a Canadian tertiary care center.PLoS One2021
35261998Detection of the novel SARS-CoV-2 European lineage B.1.177 in Ontario, Canada.J Clin Virol Plus2021
32686686Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.Nat Commun2020
30643250Molecular landmarks of tumor hypoxia across cancer types.Nat Genet2019
31591588Genome-wide germline correlates of the epigenetic landscape of prostate cancer.Nat Med2019
31092540The Paf1 Complex Broadly Impacts the Transcriptome of Saccharomyces cerevisiae.Genetics2019
30889379The Proteogenomic Landscape of Curable Prostate Cancer.Cancer Cell2019
30735634Widespread and Functional RNA Circularization in Localized Prostate Cancer.Cell2019
29681457The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression.Cell2018
29988082Prediction of acute myeloid leukaemia risk in healthy individuals.Nature2018
28067867Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.Nat Commun2017
28939825Mitochondrial mutations drive prostate cancer aggression.Nat Commun2017
28658204Tracing the origins of relapse in acute myeloid leukaemia to stem cells.Nature2017
27851734Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2017
28068672Genomic hallmarks of localized, non-indolent prostate cancer.Nature2017
27732578A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2016
26647970A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.Nat Commun2015
24723613Mapping the cellular response to small molecules using chemogenomic fitness signatures.Science2014
24944581A genome scale overexpression screen to reveal drug activity in human cells.Genome Med2014
24561123CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β⿿-adrenergic receptor.Biochem Biophys Res Commun2014
23109428Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.Mol Cell Biol2013
23797109Miniature short hairpin RNA screens to characterize antiproliferative drugs.G3 (Bethesda)2013
22928710Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents.ACS Chem Biol2012
23050238Functional analysis with a barcoder yeast gene overexpression system.G3 (Bethesda)2012
22727066Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.BMC Genomics2012
21572441Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.Nat Biotechnol2011
22035796Compound prioritization methods increase rates of chemical probe discovery in model organisms.Chem Biol2011
22102822Multiple means to the same end: the genetic basis of acquired stress resistance in yeast.PLoS Genet2011
21860376Competitive genomic screens of barcoded yeast libraries.J Vis Exp2011
21548937A comprehensive platform for highly multiplexed mammalian functional genetic screens.BMC Genomics2011
20413493Genotype to phenotype: a complex problem.Science2010
20460461Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples.Nucleic Acids Res2010
19825181A comparative analysis of DNA barcode microarray feature size.BMC Genomics2009
19622793Quantitative phenotyping via deep barcode sequencing.Genome Res2009
18622398Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers.Nat Methods2008
19043571Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells.PLoS Genet2008
18688276Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.PLoS Genet2008
17251300Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells.J Virol2007
16840529Genomic DNA functions as a universal external standard in quantitative real-time PCR.Nucleic Acids Res2006
15911630CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome.Nucleic Acids Res2005
9027364Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor.Mol Cell Endocrinol1997
8585096In vitro labeling of gonadal steroid hormone receptors in brain tissue sections.Steroids1995
7969788Vasopressin mediates hypoglycemia-induced inhibition of luteinizing hormone secretion in the ovariectomized rhesus monkey.Neuroendocrinology1994
8388404Hypoglycemia-induced inhibition of luteinizing hormone secretion in the rhesus monkey is not mediated by endogenous opioid peptides.J Clin Endocrinol Metab1993
1592876Progesterone inhibits the estrogen-induced gonadotropin surge in the rhesus monkey independent of endogenous opiates.J Clin Endocrinol Metab1992
  • 1 - 49 of 49

Recommended Authors

Lina Gao
Oregon National Primate Research Center
Career Start Year 2010
Number of shared co-authors 1
James W MacDonald
University of Washington
Career Start Year 2003
Number of shared co-authors 4
Stefan Bekiranov
University of Virginia
Career Start Year 2000
Number of shared co-authors 2
Chenwei Lin
Clinical Research Division, Fred Hutchinson Cancer Center
Career Start Year 2000
Number of shared co-authors 5
Braden Boone
HudsonAlpha Institute for Biotechnology
Career Start Year 1999
Number of shared co-authors 0
Shawn Levy
HudsonAlpha Institute for Biotechnology
Career Start Year 1999
Number of shared co-authors 0
Kerby Shedden
University of Michigan ann arbor
Career Start Year 1999
Number of shared co-authors 2
Celine Lefebvre
The Scripps Research Institute
Career Start Year 1999
Number of shared co-authors 2
Martin Hirst
University of British Columbia
Career Start Year 1998
Number of shared co-authors 26
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Career Start Year 1997
Number of shared co-authors 3
Edwin Cuppen
Hartwig Medical Foundation
Career Start Year 1997
Number of shared co-authors 19
Agnes Viale
Memorial Sloan Kettering Cancer Center
Career Start Year 1996
Number of shared co-authors 16
Steven J M Jones
University of British Columbia
Career Start Year 1995
Number of shared co-authors 64
Wolfgang Huber
Technische Universitat Munchen
Career Start Year 1995
Number of shared co-authors 17
Anthony P Orth
Genomics Institute of the Novartis Research Foundation
Career Start Year 1995
Number of shared co-authors 0
Jeremy S Caldwell
Sirna Therapeutics a former subsidiary of Merck & Co., Inc.
Career Start Year 1994
Number of shared co-authors 0
Sudhir Varma
Center for Cancer Research, National Cancer Institute
Career Start Year 1994
Number of shared co-authors 1
Gary Hardiman
Institute for Global Food Security, Queen's University Belfast
Career Start Year 1994
Number of shared co-authors 1
Marco A Marra
University of British Columbia
Career Start Year 1993
Number of shared co-authors 66
Sarah L Anzick
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Career Start Year 1993
Number of shared co-authors 1
Samuel Aparicio
University of British Columbia
Career Start Year 1993
Number of shared co-authors 25
Sofie R Salama
Genomics Institute, University of California Santa Cruz
Career Start Year 1990
Number of shared co-authors 5
Michael A Newton
University of Wisconsin School of Medicine and Public Health
Career Start Year 1990
Number of shared co-authors 1
Abdel G Elkahloun
National Human Genome Research Institute
Career Start Year 1990
Number of shared co-authors 2
John Quackenbush
Harvard T. H. Chan School of Public Health
Career Start Year 1989
Number of shared co-authors 11
Roderick V Jensen
Virginia Tech
Career Start Year 1985
Number of shared co-authors 3
Ralf Kittler
McDermott Center for Human Growth and Development.
Career Start Year 1984
Number of shared co-authors 2
Edison T Liu
USA The Jackson Laboratory Cancer Center
Career Start Year 1982
Number of shared co-authors 4
Michael Snyder
Stanford University
Career Start Year 1981
Number of shared co-authors 16
Richard M Myers
HudsonAlpha Institute for Biotechnology
Career Start Year 1980
Number of shared co-authors 14

Collaborators

Paul C Boutros
University of California los angeles
Co-authored papers 12
Robert G Bristow
University of Toronto
Co-authored papers 10
John D McPherson
Ontario Institute for Cancer Research
Co-authored papers 10
Michael Fraser
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 9
Theodorus H van der Kwast
University Health Network, University of Toronto
Co-authored papers 9
Julie Livingstone
University of California los angeles
Co-authored papers 9
Takafumi N Yamaguchi
University of California los angeles
Co-authored papers 8
Vincent Huang
Ontario Institute for Cancer Research
Co-authored papers 8
Yu-Jia Shiah
Ontario Institute for Cancer Research
Co-authored papers 7
Lee Timms
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 7
Melvin L K Chua
National Cancer Centre Singapore
Co-authored papers 6
Thomas J Hudson
Ontario Institute for Cancer Research
Co-authored papers 6
Shadrielle Melijah G Espiritu
Ontario Institute for Cancer Research
Co-authored papers 5
Marinella Gebbia
University of Toronto
Co-authored papers 5
Natalie S Fox
University of California los angeles
Co-authored papers 5
Fouad Yousif
Ontario Institute for Cancer Research
Co-authored papers 5
Charles Boone
University of Toronto
Co-authored papers 5
Jeremy Johns
Rutgers Robert Wood Johnson Medical School
Co-authored papers 4
Iain M Wallace
Novartis Institutes for BioMedical Research
Co-authored papers 4
Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 4
Jared T Simpson
Ontario Institute for Cancer Research
Co-authored papers 4
Peter J Campbell
Wellcome Sanger Institute
Co-authored papers 4
Kathleen E Houlahan
University of California los angeles
Co-authored papers 4
Bernard T??tu
Centre de Recherche du CHU de Quebec-Universite Laval (axe Oncologie)
Co-authored papers 4
Dax Torti
Ontario Institute for Cancer Research
Co-authored papers 4
Timothy Beck
Human Longevity Inc.
Co-authored papers 4
Anna Y Lee
Ontario Institute for Cancer Research
Co-authored papers 4
Robert E Denroche
Ontario Institute for Cancer Research
Co-authored papers 4
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 4
John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Release 1.2