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Author Details

Stephen C Mack
St Jude Children's Research Hospital
2009
98
47
PMIDPaper TitleJournal TitlePublished Year
36934350Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.Neuro Oncol2023
37260294A Molecular Blueprint to Targeting ALK Gene Fusions in Glioblastoma.Clin Cancer Res2023
36944298Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances.Neoplasia2023
37439870Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages.Clin Cancer Res2023
36934350Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.Neuro Oncol2023
36849558A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.Nat Cell Biol2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
36944298Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances.Neoplasia2023
37439870Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages.Clin Cancer Res2023
37260294A Molecular Blueprint to Targeting ALK Gene Fusions in Glioblastoma.Clin Cancer Res2023
36849558A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.Nat Cell Biol2023
36471070K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas.Nat Genet2022
35739422Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.Nat Cancer2022
35422502Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.Nat Cancer2022
35858326Sox9 directs divergent epigenomic states in brain tumor subtypes.Proc Natl Acad Sci U S A2022
36471070K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas.Nat Genet2022
35739422Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.Nat Cancer2022
35858326Sox9 directs divergent epigenomic states in brain tumor subtypes.Proc Natl Acad Sci U S A2022
35422502Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.Nat Cancer2022
34001927Maternal and perinatal factors are associated with risk of pediatric central nervous system tumors and poorer survival after diagnosis.Sci Rep2021
33741710ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.Cancer Discov2021
33741711<i>ZFTA</i> Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.Cancer Discov2021
34001927Maternal and perinatal factors are associated with risk of pediatric central nervous system tumors and poorer survival after diagnosis.Sci Rep2021
34045740Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.Nat Med2021
33879448Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.Cancer Discov2021
34651095Durable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an <i>NTRK2</i> Fusion: The Impact of Integrated Genomic Profiling.JCO Precis Oncol2021
33879448Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.Cancer Discov2021
33741710ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.Cancer Discov2021
33741711<i>ZFTA</i> Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.Cancer Discov2021
34651095Durable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an <i>NTRK2</i> Fusion: The Impact of Integrated Genomic Profiling.JCO Precis Oncol2021
34045740Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.Nat Med2021
32238439Targeting NAD<sup>+</sup> Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.Mol Cancer Res2020
32238439Targeting NAD<sup>+</sup> Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.Mol Cancer Res2020
32109328Invited Review: The role and contribution of transcriptional enhancers in brain cancer.Neuropathol Appl Neurobiol2020
32445698Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.Cell2020
33259802Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.Cell2020
32703768The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.Cancer Discov2020
32967858H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone.Cancer Discov2020
32663463Sub-group, Sub-type, and Cell-type Heterogeneity of Ependymoma.Cancer Cell2020
33259802Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.Cell2020
32663463Sub-group, Sub-type, and Cell-type Heterogeneity of Ependymoma.Cancer Cell2020
32967858H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone.Cancer Discov2020
32703768The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.Cancer Discov2020
32445698Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.Cell2020
32109328Invited Review: The role and contribution of transcriptional enhancers in brain cancer.Neuropathol Appl Neurobiol2020
30948495Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.J Exp Med2019
31761532Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.Cell2019
31526762Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.Cancer Cell2019
31455674Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.Cancer Discov2019
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Collaborators

Michael D Taylor
The Hospital for Sick Children
Co-authored papers 51
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 30
Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
Co-authored papers 30
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 23
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 23
Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 21
James T Rutka
Hospital for Sick Children
Co-authored papers 20
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 20
Sameer Agnihotri
Co-authored papers 20
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 19
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 18
Livia Garzia
The Research Institute of the McGill University Health Centre, McGill University
Co-authored papers 18
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 17
Peter B Dirks
The Hospital for Sick Children, University of Toronto
Co-authored papers 16
Uri Tabori
Co-authored papers 15
Xin Wang
The Chinese University of Hong Kong, Prince of Wales Hospital
Co-authored papers 15
Eric Bouffet
The Hospital for Sick Children
Co-authored papers 15
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 15
Xiaochong Wu
The Hospital for Sick Children
Co-authored papers 14
Hendrik Witt
Co-authored papers 14
Betty Luu
University of Wollongong
Co-authored papers 13
Briana C Prager
Massachusetts General Hospital
Co-authored papers 13
David J H Shih
University of Texas MD Anderson Cancer Center Houston
Co-authored papers 12
Adrian M Dubuc
Dana-Farber Cancer Institute
Co-authored papers 12
Claudia C Faria
Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN)
Co-authored papers 11
Charles G Eberhart
Wilmer Eye Institute, Johns Hopkins Medical Institutions
Co-authored papers 11
Florence M G Cavalli
Institut Curie, PSL Research University
Co-authored papers 11
David W Ellison
St. Jude Children's Research Hospital
Co-authored papers 10
Ian F Pollack
University of Pittsburgh School of Medicine
Co-authored papers 10
William A Weiss
University of California san francisco
Co-authored papers 9
Release 1.2