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Author Details

George F Mells
University of Cambridge
2006
65
29
PMIDPaper TitleJournal TitlePublished Year
35961518UK-Wide Multicenter Evaluation of Second-line Therapies in Primary Biliary Cholangitis.Clin Gastroenterol Hepatol2023
37191344Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis.Gut Microbes2023
37026715Regulation of immune responses in primary biliary cholangitis: a transcriptomic analysis of peripheral immune cells.Hepatol Commun2023
36470304FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.Nature2023
36639314Corrigendum to: "An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs" [J Hepatol 75 (2021) 572-581].J Hepatol2023
36243043Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice.Am J Pathol2023
34864633rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis.J Autoimmun2022
35609437The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study.EBioMedicine2022
35500149Commentary on "Genome-wide meta-analysis identifies novel susceptibility loci for autoimmune hepatitis type 1".Hepatology2022
35686197The National Audit of Primary Biliary Cholangitis (PBC) in the United Kingdom: Defining the Audit Dataset and Data Collection System.Cureus2022
36818800UK-PBC National Audit: a collaborative success in identifying critical shortfalls.Frontline Gastroenterol2022
36523650Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?Can J Gastroenterol Hepatol2022
36150526Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.Gastroenterology2022
32562892Effects of Primary Biliary Cholangitis on Quality of Life and Health Care Costs in the United Kingdom.Clin Gastroenterol Hepatol2021
33602855Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.Science2021
33821150Assessing efficacy of hepatocellular carcinoma prediction scores to prioritise hepatitis B surveillance in the COVID-19 era.GastroHep2021
33554101Quality of life in patients with primary biliary cholangitis: A cross-geographical comparison.J Transl Autoimmun2021
34129689The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis.Hepatology2021
33035628Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study.J Hepatol2021
32851498Understanding Fatigue in Primary Biliary Cholangitis.Dig Dis Sci2021
32446714High mortality rates for SARS-CoV-2 infection in patients with pre-existing chronic liver disease and cirrhosis: Preliminary results from an international registry.J Hepatol2020
31757316Individualizing Care: Management Beyond Medical Therapy.Surg Oncol Clin N Am2020
31850579Editorial: rapid assessment of health-related quality of life in primary biliary cholangitis-no excuse not to ask. Authors' reply.Aliment Pharmacol Ther2020
31850571Letter: histology is relevant for risk stratification in primary biliary cholangitis.Aliment Pharmacol Ther2020
30557739Pruritus Is Common and Undertreated in Patients With Primary Biliary Cholangitis in the United Kingdom.Clin Gastroenterol Hepatol2019
31664722PBC-10: a short quality of life measure for clinical screening in primary biliary cholangitis.Aliment Pharmacol Ther2019
30566748Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System.Hepatology2019
29663477The Impact of Autoimmune Hepatitis and Its Treatment on Health Utility.Hepatology2018
30017646Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.Lancet Gastroenterol Hepatol2018
29881820Clinical application of the GLOBE and United Kingdom-primary biliary cholangitis risk scores in a trial cohort of patients with primary biliary cholangitis.Hepatol Commun2018
30119881Increased sensitivity of Treg cells from patients with PBC to low dose IL-12 drives their differentiation into IFN-γ secreting cells.J Autoimmun2018
30259852Individualizing Care: Management Beyond Medical Therapy.Clin Liver Dis2018
30005861Support of precision medicine through risk-stratification in autoimmune liver diseases - histology, scoring systems, and non-invasive markers.Autoimmun Rev2018
30420264Prognostic models in primary biliary cholangitis.J Autoimmun2018
30262398Rapid disease progression in a patient with mismatch repair-deficient and cortisol secreting adrenocortical carcinoma treated with pembrolizumab.Semin Oncol2018
30507971Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis.PLoS Genet2018
27992413Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.Nat Genet2017
28326584Editorial: scoring systems in primary biliary cholangitis - time to make a move.Aliment Pharmacol Ther2017
28397694Stratified medicine and primary biliary cholangitis.Lancet Gastroenterol Hepatol2017
29081991Severe steroid-resistant anti-PD1 T-cell checkpoint inhibitor-induced hepatotoxicity driven by biliary injury.ESMO Open2017
28818518Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study.Lancet Gastroenterol Hepatol2017
26223498The UK-PBC risk scores: Derivation and validation of a scoring system for long-term prediction of end-stage liver disease in primary biliary cholangitis.Hepatology2016
27640331The inter-relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis.Aliment Pharmacol Ther2016
27604637Early primary biliary cholangitis is characterised by brain abnormalities on cerebral magnetic resonance imaging.Aliment Pharmacol Ther2016
27324985Toward precision medicine in primary biliary cholangitis.Dig Liver Dis2016
26160476Making the most of new genetic risk factors - genetic and epigenetic fine mapping of causal autoimmune disease variants.Clin Res Hepatol Gastroenterol2015
26394269International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.Nat Commun2015
24626178Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease.Cell Cycle2014
30992889Primary biliary cirrhosis: Family, genes, and bugs.Clin Liver Dis (Hoboken)2014
23246637Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid.Gastroenterology2013
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Co-authored papers 22
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Co-authored papers 20
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Co-authored papers 10
Population Health Sciences Institute, Newcastle University
Co-authored papers 10
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Co-authored papers 6
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Institute of Clinical Molecular Biology, Kiel University
Co-authored papers 2
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Co-authored papers 2
University of Toronto, Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital
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University of California davis
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Research Institute, National Center for Global Health and Medicine
Co-authored papers 2
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Co-authored papers 2
National Center for Global Health and Medicine
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Humanitas University
Co-authored papers 2
Database Center for Life Science
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
The University of Melbourne
Co-authored papers 2
Institute for Clinical and Translational Research, Baylor College of Medicine
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Chaohu Hospital Affiliated to Anhui Medical University
Co-authored papers 1
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Institute of Biomedical Technologies, National Research Council of Italy
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