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Author Details

Choh Yeung
Center for Cancer Research, National Cancer Institute
1987
26
19
PMIDPaper TitleJournal TitlePublished Year
37616468Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.Clin Cancer Res2023
37616468Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.Clin Cancer Res2023
32354737Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma.Cancer Res2020
32354737Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma.Cancer Res2020
32908120Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma.Oncogenesis2020
32908120Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma.Oncogenesis2020
31431459Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma.Cancer Res2019
31431459Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma.Cancer Res2019
27835791The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma.Transl Oncol2016
27835791The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma.Transl Oncol2016
25925378IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.Neoplasia2015
25925378IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.Neoplasia2015
24277455Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.Clin Cancer Res2014
24277455Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.Clin Cancer Res2014
23318429Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth.Oncogene2013
23318429Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth.Oncogene2013
22495974Global methylation analysis identifies PITX2 as an upstream regulator of the androgen receptor and IGF-I receptor genes in prostate cancer.Horm Metab Res2012
22495974Global methylation analysis identifies PITX2 as an upstream regulator of the androgen receptor and IGF-I receptor genes in prostate cancer.Horm Metab Res2012
23002205Identification of FoxM1/Bub1b signaling pathway as a required component for growth and survival of rhabdomyosarcoma.Cancer Res2012
23002205Identification of FoxM1/Bub1b signaling pathway as a required component for growth and survival of rhabdomyosarcoma.Cancer Res2012
21403840Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells.Neoplasia2011
21403840Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells.Neoplasia2011
21653923Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.J Natl Cancer Inst2011
21653923Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.J Natl Cancer Inst2011
19809159Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.J Clin Invest2009
19597468Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin.Oncogene2009
19809159Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.J Clin Invest2009
19597468Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin.Oncogene2009
18071913Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases.Clin Exp Metastasis2008
18071913Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases.Clin Exp Metastasis2008
17409454Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival.Cancer Res2007
17409454Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival.Cancer Res2007
14704791The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis.Nat Med2004
14704791The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis.Nat Med2004
11325848Metastasis-associated differences in gene expression in a murine model of osteosarcoma.Cancer Res2001
11325848Metastasis-associated differences in gene expression in a murine model of osteosarcoma.Cancer Res2001
10987281XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma.Cancer Res2000
18521287Autocrine Transforming Growth Factor-beta Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein.Sarcoma2000
10987281XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma.Cancer Res2000
11315100An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential.Clin Exp Metastasis2000
18521287Autocrine Transforming Growth Factor-beta Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein.Sarcoma2000
11315100An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential.Clin Exp Metastasis2000
10224065Diminished G1 checkpoint after gamma-irradiation and altered cell cycle regulation by insulin-like growth factor II overexpression.J Biol Chem1999
10224065Diminished G1 checkpoint after gamma-irradiation and altered cell cycle regulation by insulin-like growth factor II overexpression.J Biol Chem1999
8341365Induction and suppression of proto-oncogenes in rat striatum after single or multiple treatments with cocaine or GBR-12909.NIDA Res Monogr1993
8314788Production of recombinant cytochrome b558 allows reconstitution of the phagocyte NADPH oxidase solely from recombinant proteins.J Biol Chem1993
8341365Induction and suppression of proto-oncogenes in rat striatum after single or multiple treatments with cocaine or GBR-12909.NIDA Res Monogr1993
8314788Production of recombinant cytochrome b558 allows reconstitution of the phagocyte NADPH oxidase solely from recombinant proteins.J Biol Chem1993
1318579Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase.Science1992
1318579Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase.Science1992
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Collaborators

Osteosarcoma Institute
Co-authored papers 20
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Co-authored papers 11
National Cancer Institute, National Institutes of Health
Co-authored papers 10
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Co-authored papers 6
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Co-authored papers 4
Center for Biomedical Informatics and Information Technology
Co-authored papers 3
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Co-authored papers 3
National Cancer Institute, National Institutes of Health
Co-authored papers 3
University of Michigan ann arbor
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 2
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Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
University of Washington
Co-authored papers 1
Center for Sickle Cell Disease, Howard University College of Medicine
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
University of Washington
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
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Co-authored papers 1
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University of Alabama at Birmingham
Co-authored papers 1
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
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Center for Cancer Research, National Cancer Institute
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University of Alabama at Birmingham
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National Cancer Institute, National Institutes of Health
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Co-authored papers 1
Center for Applied Proteomics and Molecular Medicine, George Mason University
Co-authored papers 1
University of Texas MD Anderson Cancer Center
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