Author details

Full Name

John Leszyk

Affiliation

ORCID

Career Start Year

1986

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
31296534	Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.	Journal of Cell Biology	2019
31844661	Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy.	Science advances	2019
30593864	Selective profiling of ribosomes associated with yeast Upf proteins.	Methods	2019
30573663	HLA-DO Modulates the Diversity of the MHC-II Self-peptidome.	Molecular and Cellular Proteomics	2019
31020640	Naturally processed HLA-DR3-restricted HHV-6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T-cell responses.	Eur J Immunol	2019
30806671	Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS.	Human Molecular Genetics	2019
31195240	Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition.	iScience	2019
29273772	Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.	Nature Neuroscience	2018
30068389	RNA binding proteins co-localize with small tau inclusions in tauopathy.	Acta neuropathologica communications	2018
30318462	A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis.	Cell Chemical Biology	2018
29342175	Immunocontraceptive target repertoire defined by systematic identification of sperm membrane alloantigens in a single species.	PLoS ONE	2018
29735996	C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2.	Nat Methods	2018
29732401	Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria.	Sci Adv	2018
28096517	The nucleoside analog clitocine is a potent and efficacious readthrough agent.	RNA	2017
28377500	Innate immune signaling in is regulated by transforming growth factor Î² (TGFÎ²)-activated kinase (Tak1)-triggered ubiquitin editing.	Journal of Biological Chemistry	2017
29270531	Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant.	Kidney International Reports	2017
27926785	Identification of proximal sites for unwound DNA substrate in Escherichia coli topoisomerase I with oxidative crosslinking.	FEBS Letters	2017
28165127	Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.	Human Molecular Genetics	2017
27863537	High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.	J Extracell Vesicles	2016
27160897	Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.	Cell Reports	2016
27114527	Spatially distinct and metabolically active membrane domain in mycobacteria.	Proc Natl Acad Sci U S A	2016
26220577	Macrophage secretome from women with HIV-associated neurocognitive disorders.	Proteomics - Clinical Applications	2016
27702906	Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.	Proceedings of the National Academy of Sciences of the United States of America	2016
26695631	Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.	mBio	2015
25733896	Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3.	Proceedings of the National Academy of Sciences of the United States of America	2015
26435129	The 2012/2013 ABRF Proteomic Research Group Study: Assessing Longitudinal Intralaboratory Variability in Routine Peptide Liquid Chromatography Tandem Mass Spectrometry Analyses.	Mol Cell Proteomics	2015
26081415	Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme.	Nature Communications	2015
26208400	Interacting partners of macrophage-secreted cathepsin B contribute to HIV-induced neuronal apoptosis.	AIDS	2015
24004147	Immunodepletion plasma proteomics by tripleTOF 5600 and Orbitrap elite/LTQ-Orbitrap Velos/Q exactive mass spectrometers.	J Proteome Res	2013
24088567	Supervillin binding to myosin II and synergism with anillin are required for cytokinesis.	Mol Biol Cell	2013
23976974	Lactotransferrin in Asian elephant (Elephas maximus) seminal plasma correlates with semen quality.	PLoS ONE	2013
23084401	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	Cell	2012
30360293	The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus.	Cell	2012
22437826	Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons.	Journal of Biological Chemistry	2012
22586119	LPS remodeling is an evolved survival strategy for bacteria.	Proc Natl Acad Sci U S A	2012
20592871	Evaluation of the new MALDI matrix 4-chloro-alpha-cyanocinnamic acid.		2010
19670042	Isobaric labeling and tandem mass spectrometry: a novel approach for profiling and quantifying proteins differentially expressed in amniotic fluid in preterm labor with and without intra-amniotic infection/inflammation.	Journal of Maternal-Fetal and Neonatal Medicine	2010
20975081	Haptoglobin as an early serum biomarker of virus-induced autoimmune type 1 diabetes in biobreeding diabetes resistant and LEW1.WR1 rats.	Experimental Biology and Medicine	2010
18215134	Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes.	Biochemical Journal	2008
16687476	Proteomic analysis of rat liver phosphoproteins after treatment with protein kinase inhibitor H89 (N-(2-[p-bromocinnamylamino-]ethyl)-5-isoquinolinesulfonamide).	Journal of Pharmacology and Experimental Therapeutics	2006
15998802	Proteomic analysis of a eukaryotic cilium.	Journal of Cell Biology	2005
16140743	Characterization of an alternate form of Newcastle disease virus fusion protein.	Journal of Virology	2005
15799971	Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.	Journal of Biological Chemistry	2005
15131120	Role of insulin action and cell size on protein expression patterns in adipocytes.	Journal of Biological Chemistry	2004
15520860	Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone.	Journal of Clinical Investigation	2004
14676205	EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.	Journal of Biological Chemistry	2004
12743033	Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules.	EMBO Journal	2003
12529412	Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone.	Molecular and Cellular Biology	2003
11866508	Troponin-I interacts with the Met47 region of skeletal muscle actin. Implications for the mechanism of thin filament regulation by calcium.	Journal of Molecular Biology	2002
12202484	Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.	Journal of Biological Chemistry	2002