Skip to Main Content

Author Details

James C Whisstock
Monash University
1994
268
66
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36639734The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.Commun Biol2023
37716187Fragment-based and structure-guided discovery of perforin inhibitors.Eur J Med Chem2023
37612925Automation in Cryo-FIB Preparation, from Cellular to Tissue Structural Biology.Microsc Microanal2023
37762561A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen.Int J Mol Sci2023
37105276OpenFIBSEM: A universal API for FIBSEM control.J Struct Biol2023
37440171Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies.ACS Chem Biol2023
37198463The role of NINJ1 protein in programmed cellular destruction.Nature2023
36841236TcpA from the Clostridium perfringens plasmid pCW3 is more closely related to the DNA translocase FtsK than to coupling proteins.Structure2023
36710259Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.ChemMedChem2023
34699747Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential.Cell Chem Biol2022
35471730Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation.Immunol Cell Biol2022
35864164Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.Nat Struct Mol Biol2022
36261433Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor.Nat Commun2022
35100351A mechanism for hereditary angioedema caused by a lysine 311-to-glutamic acid substitution in plasminogen.Blood2022
35066977Macrophage self-renewal is regulated by transient expression of PDGF- and VEGF-related factor 2.FEBS J2022
35333855Mining folded proteomes in the era of accurate structure prediction.PLoS Comput Biol2022
33947796Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1.Sci Signal2021
34887559The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.Nat Struct Mol Biol2021
33936509Prediction of secondary structure population and intrinsic disorder of proteins using multitask deep learning.AMIA Annu Symp Proc2021
32126263Automated cryo-lamella preparation for high-throughput in-situ structural biology.J Struct Biol2020
33659426Assembly and Imaging set up of PIE-Scope.Bio Protoc2020
31936823Parsing the IL-37-Mediated Suppression of Inflammasome Function.Cells2020
32104500Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer.Theranostics2020
33178209Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector.Front Immunol2020
32717572Mapping the binding site of C1-inhibitor for polyanion cofactors.Mol Immunol2020
32574621Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface.Gastroenterology2020
32226543Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma.Theranostics2020
30520638Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.J Med Chem2019
30184176Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods.Brief Bioinform2019
30225958Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library.Chembiochem2019
31301349Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.J Struct Biol2019
31295457Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding.J Mol Biol2019
31209154Control of growth factor signalling by MACPF proteins.Biochem Soc Trans2019
31259689PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy.Elife2019
31537793The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.Nat Commun2019
30814058Tranexamic acid is an active site inhibitor of urokinase plasminogen activator.Blood Adv2019
30837322Structural studies of plasmin inhibition.Biochem Soc Trans2019
30526166Brentuximab vedotin in T-cell lymphoma.Expert Rev Hematol2019
29440191Torso-Like Is a Component of the Hemolymph and Regulates the Insulin Signaling Pathway in <i>Drosophila</i>.Genetics2018
30213934Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.Nat Commun2018
30111885The first transmembrane region of complement component-9 acts as a brake on its self-assembly.Nat Commun2018
29844483PhosContext2vec: a distributed representation of residue-level sequence contexts and its application to general and kinase-specific phosphorylation site prediction.Sci Rep2018
29363515Genome-Wide Screen for New Components of the <i>Drosophila melanogaster</i> Torso Receptor Tyrosine Kinase Pathway.G3 (Bethesda)2018
29416110Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.Cell Death Differ2018
28757431Perforin-A key (shaped) weapon in the immunological arsenal.Semin Cell Dev Biol2017
28088364Antibodies: From novel repertoires to defining and refining the structure of biologically important targets.Methods2017
28166206Real-time visualization of perforin nanopore assembly.Nat Nanotechnol2017
28355563Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice.Cell Rep2017
28495958Maternal Torso-Like Coordinates Tissue Folding During <i>Drosophila</i> Gastrulation.Genetics2017
29383154An ultrastructural investigation of tumors undergoing regression mediated by immunotherapy.Oncotarget2017
  • 1 - 50 of 268

Recommended Authors

David T Barkan
Novartis Institutes for BioMedical Research, Inc.
Career Start Year 2007
Number of shared co-authors 4
Lester G Carter
Stanford University
Career Start Year 2004
Number of shared co-authors 1
Marc C Deller
Incyte Corporation
Career Start Year 2000
Number of shared co-authors 1
Giselle M Knudsen
Department of Pharmaceutical Chemistry, University of California san francisco
Career Start Year 1999
Number of shared co-authors 2
Udupi A Ramagopal
Poornaprajna Institute of Scientific Research (PPISR)
Career Start Year 1998
Number of shared co-authors 1
Andrew P May
Fluidigm Corporation
Career Start Year 1997
Number of shared co-authors 0
Erik Verschueren
University of California San Francisco
Career Start Year 1997
Number of shared co-authors 1
Krzysztof Paw??owski
Kashubian Center for Heart and Vascular Diseases in Wejherowo, Pomeranian Hospitals
Career Start Year 1996
Number of shared co-authors 0
Shira Albeck
Weizmann Institute of Science
Career Start Year 1996
Number of shared co-authors 1
Orly Dym
Weizmann Institute of Science
Career Start Year 1995
Number of shared co-authors 1
Zihe Rao
Nankai University
Career Start Year 1995
Number of shared co-authors 1
Diana R Tomchick
University of Texas Southwestern Medical Center
Career Start Year 1993
Number of shared co-authors 3
Robert B Russell
Heidelberg University
Career Start Year 1991
Number of shared co-authors 2
Miha Renko
Jozef Stefan Institute
Career Start Year 1990
Number of shared co-authors 1
Natarajan Kannan
University of Georgia
Career Start Year 1990
Number of shared co-authors 1
Roland L Dunbrack
Fox Chase Cancer Center
Career Start Year 1989
Number of shared co-authors 3
Andreas Hofmann
Heidelberg University
Career Start Year 1989
Number of shared co-authors 1
Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Career Start Year 1989
Number of shared co-authors 1
Miriam Eisenstein
Weizmann Institute of Science
Career Start Year 1988
Number of shared co-authors 1
Steven C Almo
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 1
Raymond J Owens
University of Oxford
Career Start Year 1986
Number of shared co-authors 2
Randy J Read
Cambridge Institute for Medical Research, University of Cambridge
Career Start Year 1982
Number of shared co-authors 3
Charles S Craik
Department of Pharmaceutical Chemistry, University of California san francisco
Career Start Year 1980
Number of shared co-authors 8
Tom Alber
University of California berkeley
Career Start Year 1976
Number of shared co-authors 1
James A Wells
Department of Pharmaceutical Chemistry, University of California San Francisco
Career Start Year 1974
Number of shared co-authors 1
Tom L Blundell
Heartand Lung Research Institute, University of Cambridge
Career Start Year 1971
Number of shared co-authors 2
Wayne A Hendrickson
Columbia University
Career Start Year 1968
Number of shared co-authors 3
Andras Fiser
Albert Einstein College of Medicine
Career Start Year 1968
Number of shared co-authors 3
Robert M Stroud
University of California San Francisco
Career Start Year 1965
Number of shared co-authors 3
David Eisenberg
university of california los angeles
Career Start Year 1963
Number of shared co-authors 0

Collaborators

Jiangning Song
Monash Data Futures Institute, Monash University
Co-authored papers 12
Gary A Silverman
Washington University School of Medicine
Co-authored papers 10
Helen R Saibil
Institute of Structural and Molecular Biology, University of London
Co-authored papers 7
Anthony W Purcell
Monash Biomedicine Discovery Institute, Monash University
Co-authored papers 3
Chen Li
Biomedicine Discovery Institute, Monash University
Co-authored papers 2
Jacqueline A Wilce
Co-authored papers 2
Peter K Dearden
Co-authored papers 2
Yuko S Askew
Harvard Medical School, Children's Hospital
Co-authored papers 2
Scott R Burrows
Co-authored papers 2
Ross L Coppel
Nursing and Health SciencesMonash UniversityClaytonVictoriaAustralia.
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Neil D Rawlings
Co-authored papers 1
Linda S Brinen
The Joint Center for Structural Genomics, Stanford University
Co-authored papers 1
Ivan Rayment
College of Agricultural and Life Sciences, University of Wisconsin-Madison
Co-authored papers 1
Andrea Rossi
Pfizer Inc.
Co-authored papers 1
Rick K Huang
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Magnus Abrahamson
Skane University Hospital, Lund University
Co-authored papers 1
Nigel Kirby
College of Biomedical & Life Sciences, Cardiff University
Co-authored papers 1
Kailash C Gupta
National Centre for Cell Science, SP Pune University Campus
Co-authored papers 1
Saravut J Weroha
Mayo Clinic
Co-authored papers 1
Robert J Fletterick
University of California San Francisco
Co-authored papers 1
Stephanie X Wang
University of California san francisco
Co-authored papers 1
Wojtek J Goscinski
Monash eResearch Centre, Monash University
Co-authored papers 1
Paul Haluska
Mayo Clinic
Co-authored papers 1
Nicholas J Lyons
Co-authored papers 1
Maya Topf
Leibniz-Institut fur Virologie (LIV)
Co-authored papers 1
Gail P Risbridger
Biomedicine Discovery Institute, Monash University
Co-authored papers 1
Christine Orengo
University College London, Institute of Structural and Molecular Biology
Co-authored papers 1
Philip J Rosenthal
University of California at San Francisco
Co-authored papers 1
Mark C Field
University of Dundee
Co-authored papers 1
Release 1.2