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Author Details
Full Name
Kevin H Lin
Affiliation
Duke University
ORCID
Career Start Year
2014
Papers
15
H Index
10
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36918588
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis.
Nat Commun
2023
35668193
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.
Nat Cancer
2022
34706244
ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells.
Cell Rep
2021
32203462
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.
Nat Genet
2020
32826232
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Cancer Discov
2020
32553168
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers.
Cell Rep
2020
30773463
Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.
Cell Metab
2019
31517048
Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.
Sci Adv
2019
30323337
Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers.
Nat Commun
2018
30158527
Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity.
Nat Commun
2018
29931016
An acoustofluidic trap and transfer approach for organizing a high density single cell array.
Lab Chip
2018
28746882
A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution.
Cell Rep
2017
27283158
Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia.
Sci Rep
2016
26392303
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.
Nat Commun
2015
25538080
RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis.
Sci Signal
2014
1 - 15 of 15
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