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Author Details

Hyemyung Seo
Center for Bionano Intelligence Education and Research, Hanyang University
1995
68
33
PMIDPaper TitleJournal TitlePublished Year
37167915Multicomponent metal-organic framework nanocomposites for tumor-responsive synergistic therapy.J Colloid Interface Sci2023
35140411Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells.Nat Protoc2022
34921580Analysis of multi-omics data on the relationship between epigenetic changes and nervous system disorders caused by exposure to environmentally harmful substances.Environ Toxicol2022
34166773Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington's disease.Prog Neurobiol2021
33771089Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.J Enzyme Inhib Med Chem2021
33863993Brain cells derived from Alzheimer's disease patients have multiple specific innate abnormalities in energy metabolism.Mol Psychiatry2021
34045367Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson's Disease Model Mice.Biomol Ther (Seoul)2021
32422864Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease.Int J Mol Sci2020
31714896Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models.J Clin Invest2020
32402162Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease.N Engl J Med2020
31495079HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice.Exp Neurobiol2019
29706608Age-associated bimodal transcriptional drift reduces intergenic disparities in transcription.Aging (Albany NY)2018
29887985Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson's Disease.Parkinsons Dis2018
29847726Cell-Penetrating Peptide-Patchy Deformable Polymeric Nanovehicles with Enhanced Cellular Uptake and Transdermal Delivery.Biomacromolecules2018
30460108Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity.Anim Cells Syst (Seoul)2018
28190238Alpha-Synuclein Suppresses Retinoic Acid-Induced Neuronal Differentiation by Targeting the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway.Mol Neurobiol2018
27798112Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation.Hum Mol Genet2017
28288000Age-associated chromatin relaxation is enhanced in Huntington's disease mice.Aging (Albany NY)2017
28985749Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21<sup>WAF1/CIP1</sup> expression.Mol Brain2017
28958936Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and LRRK2 G2019S Parkinson's disease model mice challenged with lipopolysaccharide.Biochem Biophys Res Commun2017
25407931MiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons.Mol Neurobiol2016
27242267β-Lapachone increases phase II antioxidant enzyme expression via NQO1-AMPK/PI3K-Nrf2/ARE signaling in rat primary astrocytes.Free Radic Biol Med2016
27314038G2385R and I2020T Mutations Increase LRRK2 GTPase Activity.Biomed Res Int2016
26944602Gene therapy by proteasome activator, PA28γ, improves motor coordination and proteasome function in Huntington's disease YAC128 mice.Neuroscience2016
25976370Neuroanatomical Visualization of the Impaired Striatal Connectivity in Huntington's Disease Mouse Model.Mol Neurobiol2016
25605758An early endosome regulator, Rab5b, is an LRRK2 kinase substrate.J Biochem2015
26384650Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression.Mol Brain2015
26317805Enhancement of BACE1 Activity by p25/Cdk5-Mediated Phosphorylation in Alzheimer's Disease.PLoS One2015
26365310LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase.Nat Commun2015
26133660Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease.Brain2015
25982323Reduction of Nfia gene expression and subsequent target genes by binge alcohol in the fetal brain.Neurosci Lett2015
24333873Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington's disease model mice.Biochem Biophys Res Commun2014
25478574Increased DJ-1 in urine exosome of Korean males with Parkinson's disease.Biomed Res Int2014
25193078JMJD2A attenuation affects cell cycle and tumourigenic inflammatory gene regulation in lipopolysaccharide stimulated neuroectodermal stem cells.Exp Cell Res2014
25086961Prediction of miRNA-mRNA associations in Alzheimer's disease mice using network topology.BMC Genomics2014
24559646miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling.Neurobiol Aging2014
24607701Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain.Neurochem Int2014
24568732Age-dependent effects of valproic acid in Alzheimer's disease (AD) mice are associated with nerve growth factor (NGF) regulation.Neuroscience2014
23949442LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.Exp Mol Med2013
24334988Development of electrochemical microbiochip for the biological diagnosis of Neisseria gonorrhoeae.Anal Sci2013
24213601EPITRANS: a database that integrates epigenome and transcriptome data.Mol Cells2013
22764206Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.Sci Transl Med2012
20696760Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.J Biol Chem2010
20698932The hAPP-YAC transgenic model has elevated UPS activity in the frontal cortex similar to Alzheimer's disease and Down's syndrome.J Neurochem2010
19240033SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition.J Biol Chem2009
18005339Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.J Neurochem2008
18640989Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.Hum Mol Genet2008
17053214Efficient induction of oligodendrocytes from human embryonic stem cells.Stem Cells2007
17600316Regulation of functional phenotypes of cord blood derived eosinophils by gamma-secretase inhibitor.Am J Respir Cell Mol Biol2007
17327906Proteasome activator enhances survival of Huntington's disease neuronal model cells.PLoS One2007
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Collaborators

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Co-authored papers 2
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Co-authored papers 2
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Weill Cornell Medicine/New York Presbyterian Hospital
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