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Author Details

Shweta Joshi
Moores Cancer Center, University of California
2007
39
20
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37306759Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma.Cancer Res2023
37350973Targeting macrophage Syk enhances responses to immune checkpoint blockade and radiotherapy in high-risk neuroblastoma.Front Immunol2023
35122833Targeting myeloid-derived suppressor cells to enhance natural killer cell-based immunotherapy.Pharmacol Ther2022
36620102Perioperative Challenges in the Management of Rhino-Orbital Cerebral Mucormycosis: An Observational Study from a Tertiary Care Hospital.Anesth Essays Res2022
33480647Augmented Antitumor Activity for Novel Dual PI3K/BDR4 Inhibitors, SF2523 and SF1126 in Ewing Sarcoma.J Pediatr Hematol Oncol2021
33681757Incapacity in childbirth - Rare or common?Eur J Obstet Gynecol Reprod Biol X2021
33872215Rapid Multiplex Loop-Mediated Isothermal Amplification (m-LAMP) Assay for Differential Diagnosis of Leprosy and Post-Kala-Azar Dermal Leishmaniasis.Am J Trop Med Hyg2021
33669187BTK Inhibition Reverses MDSC-Mediated Immunosuppression and Enhances Response to Anti-PDL1 Therapy in Neuroblastoma.Cancers (Basel)2021
34557659The BTK/PI3K/BRD4 axis inhibitor SRX3262 overcomes Ibrutinib resistance in mantle cell lymphoma.iScience2021
34219438Development of a novel loop-mediated isothermal amplification assay for rapid detection of Mycobacterium leprae in clinical samples.Indian J Dermatol Venereol Leprol2021
32722460Targeting the Tumor Microenvironment in Neuroblastoma: Recent Advances and Future Directions.Cancers (Basel)2020
31974273Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression.Mol Cancer Ther2020
32793389A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity.Cell Discov2020
32983125"Re-educating" Tumor Associated Macrophages as a Novel Immunotherapy Strategy for Neuroblastoma.Front Immunol2020
30853982Combinatorial Approach to Improve Cancer Immunotherapy: Rational Drug Design Strategy to Simultaneously Hit Multiple Targets to Kill Tumor Cells and to Activate the Immune System.J Oncol2019
30071568Erratum to: Vascular Permeability and Remodelling Coincide with Inflammatory and Reparative Processes after Joint Bleeding in Factor VIII-Deficient Mice.Thromb Haemost2019
31018997SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer.Mol Cancer Ther2019
29475942Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication.J Biol Chem2018
29847841Vascular Permeability and Remodelling Coincide with Inflammatory and Reparative Processes after Joint Bleeding in Factor VIII-Deficient Mice.Thromb Haemost2018
28817691Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.PLoS One2017
28137841Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis.Proc Natl Acad Sci U S A2017
26938241PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.PLoS One2016
28881723Association of high microvessel α<sub>v</sub>β<sub>3</sub> and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126.Oncotarget2016
27496136Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma.Mol Cancer Ther2016
25578041Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma.Cancer Chemother Pharmacol2015
26257191Vascular remodeling underlies rebleeding in hemophilic arthropathy.Am J Hematol2015
24162827PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression.J Neurooncol2014
25425962Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12)â¿¿V-Ha-Ras transgenic mouse glioma model.Cancer Cell Int2014
24982421MDM2 regulates hypoxic hypoxia-inducible factor 1α stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner.J Biol Chem2014
25103499A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1α and HIF2α stability and tumor growth, angiogenesis, and metastasis.Mol Cancer Res2014
24770346Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo.PLoS One2014
24886428A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.BMC Immunol2014
24881819PTEN and PI-3 kinase inhibitors control LPS signaling and the lymphoproliferative response in the CD19+ B cell compartment.Exp Cell Res2014
24309609Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors.J Pediatr Hematol Oncol2014
22906884Purification and characterization of phosphoenolpyruvate carboxykinase from Raillietina echinobothrida, a cestode parasite of the domestic fowl.Parasitology2013
19756573Guanidine hydrochloride and urea-induced unfolding of Brugia malayi hexokinase.Eur Biophys J2010
18456347Molecular cloning and characterization of Plasmodium falciparum transketolase.Mol Biochem Parasitol2008
18499511Molecular cloning and characterization of Brugia malayi hexokinase.Parasitol Int2008
18001110DNA binding and topoisomerase II inhibitory activity of water-soluble ruthenium(II) and rhodium(III) complexes.Inorg Chem2007
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Collaborators

Atrium Health-Levine Cancer Institute
Co-authored papers 24
university of california san diego Department of Pediatrics, University of California
Co-authored papers 21
university of california san diego Department of Pediatrics, University of California
Co-authored papers 7
Co-authored papers 3
Stanford University School of Medicine
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of San Diego
Co-authored papers 2
Rady Children's Hospital San Diego.
Co-authored papers 2
Herbert Wertheim School of Public Health, University of California San Diego
Co-authored papers 2
Moores Cancer Center, university of california san diego Health System
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Data4Cure Inc.
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Co-authored papers 1
Van Andel Institute
Co-authored papers 1
Tokyo Medical and Dental University Hospital
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California San Diego
Co-authored papers 1