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Author Details

Steven A Goldman
Center for Translational Neuromedicine, University of Rochester Medical Center
1982
183
76
PMIDPaper TitleJournal TitlePublished Year
37460676Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain.Nat Biotechnol2024
36334067Glial progenitor cells of the adult human white and grey matter are contextually distinct.Glia2023
37968397Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema.Nature2023
37219367Astrocytes as master modulators of neural networks: Synaptic functions and disease-associated dysfunction of astrocytes.Ann N Y Acad Sci2023
37279261Astrocytic engagement of the corticostriatal synaptic cleft is disrupted in a mouse model of Huntington's disease.Proc Natl Acad Sci U S A2023
36864567Astrocytic contributions to Huntington's disease pathophysiology.Ann N Y Acad Sci2023
35262656Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder.Brain2022
36044851A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice.Cell Rep2022
36213002Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.Cancer Res Commun2022
36261421P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells.Nat Commun2022
36261010A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration.Cell Rep2022
33414060Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic.Semin Cell Dev Biol2021
33589835Reactive astrocyte nomenclature, definitions, and future directions.Nat Neurosci2021
33749919Cell Therapy for Huntington's Disease: Learning from Failure.Mov Disord2021
34152047Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model.Cell Prolif2021
34172753Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes.Nat Commun2021
34233199Cell-intrinsic glial pathology is conserved across human and murine models of Huntington's disease.Cell Rep2021
34048692ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.Stem Cell Reports2021
32449961Glial evolution as a determinant of human behavior and its disorders.Ann N Y Acad Sci2020
31704113Glial cells in schizophrenia: a unified hypothesis.Lancet Psychiatry2020
33004510Glymphatic failure as a final common pathway to dementia.Science2020
32976765Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons.Stem Cell Reports2020
32763144The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis.Cell Stem Cell2020
30554964Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation.Cell Stem Cell2019
31242417Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling.Cell Rep2019
31585094Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.Cell Stem Cell2019
31285774Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease.Theranostics2019
30820907Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease.Methods Mol Biol2019
29478609Neurogenetics of Pelizaeus-Merzbacher disease.Handb Clin Neurol2018
29634690Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys.Nat Med2018
29742388The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?Stem Cell Reports2018
27882623Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.Stem Cells2017
28366443Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes.Am J Hum Genet2017
28336567SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions.J Neurosci2017
28554396Progenitor cell-based treatment of glial disease.Prog Brain Res2017
28825601Patience pays in spinal repair.J Clin Invest2017
28578789Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease.Trends Neurosci2017
28736215Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia.Cell Stem Cell2017
26755608Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier.Proc Natl Acad Sci U S A2016
26616854PAR1 inhibition suppresses the self-renewal and growth of A2B5-defined glioma progenitor cells and their derived gliomas in vivo.Oncogene2016
27273432Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.Nat Commun2016
27326936Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.Dev Cell2016
27170209Glial progenitor cell-based treatment of the childhood leukodystrophies.Exp Neurol2016
27524440Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy.Cell Stem Cell2016
275485763K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice.Nat Med2016
26859354Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.Dev Cell2016
27066643BRAIN DRAIN.Sci Am2016
26955760Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation.Nat Commun2016
26849304Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.Cell Stem Cell2016
25684057Disease specific therapies in leukodystrophies and leukoencephalopathies.Mol Genet Metab2015
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Collaborators

Vance P Lemmon
Co-authored papers 4
David H Rowitch
Wellcome Trust-Medical Research Council Stem Cell Institute and.
Co-authored papers 4
Daniel H Geschwind
University of California los angeles
Co-authored papers 4
Nancy Ann Oberheim Bush
University of California san francisco
Co-authored papers 4
Paul J Tesar
Co-authored papers 4
Guy M McKhann
New York Presbyterian Hospital, Columbia University Medical Center
Co-authored papers 4
Melissa K Carpenter
Carpenter Group Consulting Inc., USA NxCell Inc., USA Q Therapeutics Inc.
Co-authored papers 3
Riki Kawaguchi
Co-authored papers 3
Jun Takahashi
Center for iPS Cell Research and Application, Kyoto University
Co-authored papers 2
Mahendra S Rao
Institute of Stem Cells and Regenerative Medicine (inStem)
Co-authored papers 2
Eric N Olson
Co-authored papers 2
Yu Qin
Co-authored papers 2
George Q Daley
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
Leslie M Thompson
Co-authored papers 2
Giovanni Coppola
David Geffen School of Medicine, University of California los angeles
Co-authored papers 2
Robert L Findling
Virginia Commonwealth University
Co-authored papers 2
Amander T Clark
Center for Reproductive Science, University of California los angeles
Co-authored papers 2
Roger A Barker
John Van Geest Center for Brain Repair, University of Cambridge
Co-authored papers 2
E Clayton
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 1
Jeffrey P Kahn
Berman Institute of Bioethics, Johns Hopkins University
Co-authored papers 1
Nimet Maherali
Co-authored papers 1
Jeongwu Lee
Lerner Research Institute, Cleveland Clinic
Co-authored papers 1
Yali Cong
Department of Medical Ethics and Law, Peking University Health Science Center
Co-authored papers 1
Kazuto Kato
Osaka University
Co-authored papers 1
Hiromitsu Nakauchi
Advanced Research Institute, Tokyo Medical and Dental University
Co-authored papers 1
Tom L Beauchamp
The Kennedy Institute of Ethics, Georgetown University
Co-authored papers 1
Ming Zhan
Ningbo First Hospital, Zhejiang University
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Nuria Montserrat
Catalan Institution for Research and Advanced Studies (ICREA)
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Release 1.2