Author details

Full Name

Anette P Gjesing

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37235780	Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes.		2023
37091798	Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing.		2023
37090505	Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists.		2023
36649380	A novel splice-affecting variant with large population impact on diabetes in Greenland.		2023
37008541	Identification of pathogenic variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment.		2023
36400171	14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes.	Diabetes Res Clin Pract	2022
36407475	Monogenic diabetes variants in Emirati women with gestational diabetes are associated with risk of non-autoimmune diabetes within 5 years after pregnancy.	Metabol Open	2022
32944759	Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.	Journal of Clinical Endocrinology and Metabolism	2021
32921795	Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations.	International Journal of Obesity	2021
33324081	Maturity-Onset Diabetes of the Young Identified Among Algerian Probands with Early-Onset Diabetes.	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy	2020
31253982	Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.	Nat Genet	2019
30629617	Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes.	PLoS ONE	2019
31488071	Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report.	BMC Medical Genetics	2019
31415576	Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants.	PLoS ONE	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
30514227	Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study.	BMC Medical Genetics	2018
30442103	Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity.	BMC Medical Genetics	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29548277	Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses.	BMC Genet	2018
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
27986810	Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function.	Journal of Biological Chemistry	2017
28341696	A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.	Diabetes	2017
28490609	A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.	Diabetes	2017
28414270	Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.	eLife	2017
29264522	High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus.	Journal of the Endocrine Society	2017
29257133	Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2017
27699707	Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk.	Endocrine	2017
28220878	Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins.	Scientific Reports	2017
27594926	DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance.	Clinical Epigenetics	2016
27398621	The genetic architecture of type 2 diabetes.	Nature	2016
27029739	Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.	Nature Communications	2016
26607294	Renin angiotensinogen system gene polymorphisms and essential hypertension among people of West African descent: a systematic review.	Journal of Human Hypertension	2016
27618447	Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.	Nat Genet	2016
27846319	Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology.	PLoS ONE	2016
27876822	A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.	Nat Commun	2016
26197239	Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes.	PLoS ONE	2015
25927630	Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes.	BMC Medical Genetics	2015
25799151	The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes.	PLoS ONE	2015
25625282	Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.	PLoS Genet	2015
25660259	Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data.	Diabetologia	2015
24604100	High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients.	Diabetologia	2014
24476040	Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model.	BMC Genetics	2014
25043022	A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.	Nature	2014
24698406	Lessons from whole-exome sequencing in MODYX families.	Diabetes Research and Clinical Practice	2014
23224494	Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes.	Diabetologia	2013
23674605	The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.	Diabetes	2013
21953277	Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.	Diabetologia	2012
22349073	Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits.	Diabetologia	2012