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Author Details

Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
2003
205
56
PMIDPaper TitleJournal TitlePublished Year
36914816SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.Nat Cancer2023
37894327Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms.Cancers (Basel)2023
37683456Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.Biochem Biophys Res Commun2023
37453329An electrophilic fragment screening for the development of small molecules targeting caspase-2.Eur J Med Chem2023
37244126Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4.Redox Biol2023
36976909Target Class Profiling of Small-Molecule Methyltransferases.ACS Chem Biol2023
36914816SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.Nat Cancer2023
37894327Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms.Cancers (Basel)2023
37683456Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.Biochem Biophys Res Commun2023
37453329An electrophilic fragment screening for the development of small molecules targeting caspase-2.Eur J Med Chem2023
37244126Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4.Redox Biol2023
36976909Target Class Profiling of Small-Molecule Methyltransferases.ACS Chem Biol2023
33481411Correlation Between Symptom Clusters and Quality of Life in Children With Acute Leukemia During Chemotherapy.Cancer Nurs2022
35648838Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.ACS Infect Dis2022
36151566Preclinical assessment of synergistic efficacy of MELK and CDK inhibitors in adrenocortical cancer.J Exp Clin Cancer Res2022
36268125Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen.ACS Pharmacol Transl Sci2022
35357819Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity.J Chem Inf Model2022
35404596Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV-2 Cell-Entry Inhibitors.J Chem Inf Model2022
36439493Terfenadine resensitizes doxorubicin activity in drug-resistant ovarian cancer cells <i>via</i> an inhibition of CaMKII/CREB1 mediated ABCB1 expression.Front Oncol2022
33481411Correlation Between Symptom Clusters and Quality of Life in Children With Acute Leukemia During Chemotherapy.Cancer Nurs2022
35312769GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling.Mol Cancer Ther2022
35169799A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.bioRxiv2022
34417224PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by <i>NSD2</i> Mutation in Pediatric Acute Lymphoblastic Leukemia.Cancer Discov2022
35086793A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry.SLAS Discov2022
35103473Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor.J Chem Inf Model2022
34472587Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments.Brief Bioinform2022
35648838Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.ACS Infect Dis2022
35404596Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV-2 Cell-Entry Inhibitors.J Chem Inf Model2022
35357819Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity.J Chem Inf Model2022
36439493Terfenadine resensitizes doxorubicin activity in drug-resistant ovarian cancer cells <i>via</i> an inhibition of CaMKII/CREB1 mediated ABCB1 expression.Front Oncol2022
36268125Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen.ACS Pharmacol Transl Sci2022
36151566Preclinical assessment of synergistic efficacy of MELK and CDK inhibitors in adrenocortical cancer.J Exp Clin Cancer Res2022
35312769GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling.Mol Cancer Ther2022
35086793A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry.SLAS Discov2022
35169799A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.bioRxiv2022
35103473Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor.J Chem Inf Model2022
34472587Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments.Brief Bioinform2022
34417224PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by <i>NSD2</i> Mutation in Pediatric Acute Lymphoblastic Leukemia.Cancer Discov2022
33468482Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen.Antimicrob Agents Chemother2021
33689873Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection.Bioorg Med Chem Lett2021
33468482Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen.Antimicrob Agents Chemother2021
33831697Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay.Bioorg Med Chem2021
34144038Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles.J Biol Chem2021
33932049Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.EMBO J2021
33822623Discovery and Optimization of 2<i>H</i>-1λ<sup>2</sup>-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer.J Med Chem2021
34136758Discovery of TMPRSS2 Inhibitors from Virtual Screening as a Potential Treatment of COVID-19.ACS Pharmacol Transl Sci2021
33708112Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.Front Pharmacol2021
33300000Minimal information for Chemosensitivity assays (MICHA): A next-generation pipeline to enable the FAIRification of drug screening experiments.bioRxiv2021
33346633The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.ACS Infect Dis2021
33398276Discovery of TMPRSS2 inhibitors from virtual screening.bioRxiv2021
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Collaborators

Roel Vermeulen
Co-authored papers 39
Anton Simeonov
Co-authored papers 37
Matthew B Boxer
Co-authored papers 35
Stephen J Chanock
National Cancer Institute, National Institutes of Health
Co-authored papers 32
Meredith Yeager
Frederick National Laboratory for Cancer Research
Co-authored papers 22
Craig J Thomas
Center for Cancer Research, National Cancer Institute
Co-authored papers 18
Sam Michael
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 17
Zhuyin Li
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 14
Sonja I Berndt
Co-authored papers 14
Christopher P Austin
St. George's University Medical School
Co-authored papers 14
Ajit Jadhav
Co-authored papers 14
Robert Welch
Co-authored papers 13
Neil E Caporaso
National Cancer Institute, National Institutes of Health
Co-authored papers 11
Richard B Hayes
Co-authored papers 10
Electron Kebebew
Stanford University School of Medicine
Co-authored papers 10
Lisa Zhang
National Institute of Child Health and Development
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Yaqin Zhang
Jiangsu University Zhenjiang 212013
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Myriem Boufraqech
The University of Texas at Austin
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Lewis C Cantley
Co-authored papers 8
Marc Ferrer
National Institutes of Health, National Center for Advancing Translational Sciences
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Donald C Lo
National Center for Advancing Translational Sciences
Co-authored papers 6
Martin J Walsh
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 6
Demetrius Albanes
Co-authored papers 5
Paolo Boffetta
Co-authored papers 5
Stephanie J Weinstein
Co-authored papers 5
Naris Nilubol
Center for Cancer Research
Co-authored papers 5
Jarmo Virtamo
Co-authored papers 4
Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 4
Amit Mehta
Center for Cancer Research, Maryland. Geisel School of Medicine at Dartmouth
Co-authored papers 4
Joseph F Fraumeni
National Cancer Institute
Co-authored papers 4
Release 1.2