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Author Details

Martin Enge
Karolinska Institutet
2004
30
20
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37370141Stem cell-derived brainstem mouse astrocytes obtain a neurotoxic phenotype in vitro upon neuroinflammation.J Inflamm (Lond)2023
35062962An overlooked subset of Cx3cr1<sup>wt/wt</sup> microglia in the Cx3cr1<sup>CreER-Eyfp/wt</sup> mouse has a repopulation advantage over Cx3cr1<sup>CreER-Eyfp/wt</sup> microglia following microglial depletion.J Neuroinflammation2022
35733248Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development.Proc Natl Acad Sci U S A2022
35388014Elastic dosage compensation by X-chromosome upregulation.Nat Commun2022
33384332Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors.Proc Natl Acad Sci U S A2021
34417326Spinal Cord Injury Induces Permanent Reprogramming of Microglia into a Disease-Associated State Which Contributes to Functional Recovery.J Neurosci2021
34253926An unsupervised method for physical cell interaction profiling of complex tissues.Nat Methods2021
33068522A Highly Scalable Method for Joint Whole-Genome Sequencing and Gene-Expression Profiling of Single Cells.Mol Cell2020
30944357Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas.Sci Rep2019
28965763Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.Cell2017
28486110Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis.Cancer Cell2017
28215845Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.Cell Metab2017
25695508Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.Nat Commun2015
26550823DNA-dependent formation of transcription factor pairs alters their binding specificity.Nature2015
26053496CTCF/cohesin-binding sites are frequently mutated in cancer.Nat Genet2015
26060301A survey of human brain transcriptome diversity at the single cell level.Proc Natl Acad Sci U S A2015
23332764DNA-binding specificities of human transcription factors.Cell2013
23953112Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites.Cell2013
22773839Protein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivo.J Biol Chem2012
23118011Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.Science2012
21941086Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.Cell Cycle2011
22101854Counting absolute numbers of molecules using unique molecular identifiers.Nat Methods2011
21868628MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.Science2011
21862591Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer.J Biol Chem2011
20378718Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities.Genome Res2010
20517297Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.EMBO J2010
19249676MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53.Cancer Cell2009
19411072Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis.Cancer Cell2009
19071110Tumor-specific induction of apoptosis by a p53-reactivating compound.Exp Cell Res2009
15558054Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.Nat Med2004
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Collaborators

Co-authored papers 10
Co-authored papers 6
Stanford University
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Stanford University School of Medicine
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University of Toronto
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Fudan University Shanghai Cancer
Co-authored papers 3
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Co-authored papers 2
University of Helsinki
Co-authored papers 2
The University of North Carolina at Chapel Hill
Co-authored papers 2
Stanford University School of Medicine
Co-authored papers 1
Mission Therapeutics Ltd. Glenn Berge Building
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University of Virginia
Co-authored papers 1
University of Virginia Health System
Co-authored papers 1
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Stanford University
Co-authored papers 1
university of california los angeles Jonsson Comprehensive Cancer Center.
Co-authored papers 1
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Karolinska Institute
Co-authored papers 1
Center for Public Health Genomics, University of Virginia
Co-authored papers 1
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
CNRS, Aix-Marseille Universite
Co-authored papers 1