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Author Details

Diego Pasini
European Institute of Oncology IRCCS
2003
69
43
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36865140Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1.bioRxiv2023
37189167Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity.Genome Med2023
37030288PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.Mol Cell2023
34426021Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer.Trends Genet2022
35422437Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis.Life Sci Alliance2022
33398338Intestinal differentiation involves cleavage of histone H3 N-terminal tails by multiple proteases.Nucleic Acids Res2021
34672740Identification of a choroid plexus vascular barrier closing during intestinal inflammation.Science2021
34818537Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality.Cell Rep2021
34186021BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation.Mol Cell2021
34078594Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair.Sci Adv2021
34331441Correction to 'Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes'.Nucleic Acids Res2021
32759276Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype.Sci Transl Med2020
31999646Dysfunctional polycomb transcriptional repression contributes to lamin A/C-dependent muscular dystrophy.J Clin Invest2020
31965581Cooperation Between MYC and β-Catenin in Liver Tumorigenesis Requires Yap/Taz.Hepatology2020
31995759PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin.Cell Rep2020
31883952Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression.Mol Cell2020
31106267Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type-dependent outcomes.Sci Adv2019
31311845Correction for Danovi et al., "Amplification of <i>Mdmx</i> (or <i>Mdm4</i>) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity".Mol Cell Biol2019
30976011Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity.Nat Commun2019
31029542Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities.Mol Cell2019
29233846VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression.Circ Res2018
30174307Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies.Cell Metab2018
29606589The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.Mol Cell2018
27846373Control of adult intestinal identity by the Polycomb repressive machinery.Cell Cycle2017
28338656Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.Cell Death Differ2017
28554894Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.EMBO J2017
27214556Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development.J Clin Invest2016
26526724Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.Cell Stem Cell2016
27585866PRC2 preserves intestinal progenitors and restricts secretory lineage commitment.EMBO J2016
27730210Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.Sci Adv2016
27659970Mapping the Function of Polycomb Proteins.Methods Mol Biol2016
27863221The Dual Role of EPOP and Elongin BC in Controlling Transcriptional Activity.Mol Cell2016
27708717EpiMINE, a computational program for mining epigenomic data.Epigenetics Chromatin2016
27151431Emerging roles for Polycomb proteins in cancer.Curr Opin Genet Dev2016
24931166Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer.Oncogene2015
25315766The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?FEBS J2015
24289921Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity.Mol Cell2014
26484139Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell.Genom Data2014
24813883Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions.Cell Rep2014
24728135Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.Nat Commun2014
23016854Regulation and function of DNA and histone methylations.Curr Pharm Des2013
23889513Precision mapping of coexisting modifications in histone H3 tails from embryonic stem cells by ETD-MS/MS.Anal Chem2013
23456257Epigenetic methylations and their connections with metabolism.Cell Mol Life Sci2013
23352454Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.Mol Cell2013
22210892Yin Yang 1 extends the Myc-related transcription factors network in embryonic stem cells.Nucleic Acids Res2012
21174538Epigenetic factors in cancer development: polycomb group proteins.Future Oncol2011
21892963Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells.Epigenetics Chromatin2011
20075857JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.Nature2010
20123906Polycomb complexes act redundantly to repress genomic repeats and genes.Genes Dev2010
20150217Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36.Mol Cell Proteomics2010
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The Institute of Cancer Research
Co-authored papers 27
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Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 12
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Institut Curie, PSL Research University, CNRS
Co-authored papers 10
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Co-authored papers 10
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Eric Conway
Conway Institute, University College Dublin
Co-authored papers 4
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VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 4
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RIKEN Research Center for Allergy and Immunology
Co-authored papers 3
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Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia (FPO) - IRCCS
Co-authored papers 3
Eugene T Dillon
Conway Institute of Biomolecular and Biomedical Research
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Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
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Iros Barozzi
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Giorgio Oliviero
University College Dublin
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Alberto Briganti
IRCCS San Raffaele Scientific Institute
Co-authored papers 2
Ariane Watson
University College Dublin
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Livio Trusolino
Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 2
Kieran Wynne
University College Dublin
Co-authored papers 2
Eleanor Glancy
Smurfit Institute of Genetics, Trinity College Dublin
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Gundula Streubel
Smurfit Institute of Genetics, Trinity College Dublin
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Darren J Fitzpatrick
Smurfit Institute of Genetics, Trinity College Dublin
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Gian Luca Negri
British Columbia Cancer Research Institute
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Beatrice Bodega
University of Milan
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Andrea Bertotti
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Karsten Hokamp
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Release 1.2