Author details

Full Name

Lam C Tsoi

Affiliation

ORCID

Career Start Year

2007

Papers

157

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37978863	Monogenic etiologies of persistent human papillomavirus infections: A comprehensive systematic review.	Genet Med	2024
36428114	Novel insights into atopic dermatitis.	Journal of Allergy and Clinical Immunology	2023
38085213	Genetic and Immunological Pathogenesis of Atopic Dermatitis.		2023
37915001	Serial KinderMiner (SKiM) discovers and annotates biomedical knowledge using co-occurrence and transformer models.	BMC Bioinformatics	2023
37873414	GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.	medRxiv	2023
37672660	Retrospective pharmacogenetic study of psoriasis highlights the role of KLK7 in TNF signaling.		2023
37612031	A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization.	J Invest Dermatol	2023
37606044	Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia.	JCI Insight	2023
37506977	Single-cell profiling of prurigo nodularis demonstrates immune-stromal crosstalk driving profibrotic responses and reversal with nemolizumab.		2023
37471166	Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis.	JCI Insight	2023
37471168	Pansclerotic morphea is characterized by IFN-Î³ responses priming dendritic cell fibroblast crosstalk to promote fibrosis.		2023
37414396	MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy.	Kidney Int	2023
37397987	Serial KinderMiner (SKiM) Discovers and Annotates Biomedical Knowledge Using Co-Occurrence and Transformer Models.	bioRxiv	2023
37325923	The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase-Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development.		2023
37323656	A partitioned 88-loci psoriasis genetic risk score reveals HLA and non-HLA contributions to clinical phenotypes in a Newfoundland psoriasis cohort.		2023
37308489	Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.		2023
37261358	Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model.	Front Immunol	2023
37127916	Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase-Signal Transducers and Activators of Transcription Signaling.		2023
37066246	tauFisher accurately predicts circadian time from a single sample of bulk and single-cell transcriptomic data.		2023
37028702	Gene Expression Signatures in Inflammatory and Sclerotic Morphea Skin and Sera Distinguish Morphea from Systemic Sclerosis.	J Invest Dermatol	2023
36928117	Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-Îº activation and APOBEC3G induction.		2023
36906125	A Cross-Trait Genetic Correlation Study Identified Eight Diseases and Traits Associated with Psoriasis.	J Invest Dermatol	2023
36899474	Relationship between genetically proxied vitamin D andÂ psoriasis risk: a Mendelian randomization study.		2023
36870556	Genetic Validation of Psoriasis Phenotyping in UK Biobank Supports the Utility of Self-Reported Data and Composite Definitions for Large Genetic and Epidemiological Studies.	J Invest Dermatol	2023
36750564	Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus.		2023
36749126	Genome-Wide Association Study in Acute Tubulointerstitial Nephritis.	J Am Soc Nephrol	2023
36732947	Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin.		2023
36716917	Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.		2023
36704840	Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin.	Arthritis Rheumatol	2023
36692020	Vitamin D3 and deconvoluting a rash.		2023
36127466	Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair.	Cellular and Molecular Immunology	2022
35945607	Enhanced rare disease mapping for phenome-wide genetic association in the UK Biobank.	Genome Medicine	2022
35943798	Tofacitinib blocks IFN-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial.	JCI insight	2022
35900871	Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes.	JCI insight	2022
35867799	TREM2 macrophages induced by human lipids drive inflammation in acne lesions.	Sci Immunol	2022
35862195	Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G.	JCI insight	2022
35856022	Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation.	iScience	2022
35812380	Editorial: Advances in Using Big Data and Artificial Intelligence to Understand Heterogeneity in Inflammatory Responses.	Frontiers in Immunology	2022
33495304	<i>DDX58</i>(RIG-I)-related disease is associated with tissue-specific interferon pathway activation.	J Med Genet	2022
35764530	Alcohol consumption and smoking in relation to psoriasis: a Mendelian randomization study.	British Journal of Dermatology	2022
35762613	Single-cell Transcriptomics Reveals Dynamic Role of Smooth Muscle Cells and Enrichment of Immune Cell Subsets in Human Abdominal Aortic Aneurysms.	Annals of Surgery	2022
35583923	Correction: Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.	eLife	2022
35572606	Roles Played by Stress-Induced Pathways in Driving Ethnic Heterogeneity for Inflammatory Skin Diseases.	Frontiers in Immunology	2022
35559048	Skin-Expressing lncRNAs in Inflammatory Responses.	Frontiers in Genetics	2022
35529773	Clinical outcomes in a cohort of patients with cutaneous T-cell lymphoma and COVID-19.	JAAD International	2022
35476593	Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation.	Sci Transl Med	2022
35362630	Relationship between periodontitis and psoriasis: A two-sample Mendelian randomization study.	Journal of Clinical Periodontology	2022
35358091	IFN-Îº is critical for normal wound repair and is decreased in diabetic wounds.	JCI insight	2022
35290245	Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney.	JCI Insight	2022
35143422	Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.	J Clin Invest	2022