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Author Details

Christina Curtis
Stanford University School of Medicine
2004
90
41
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37524958PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes.Nat Biotechnol2024
36711882Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.bioRxiv2023
37258665Deterministic evolution and stringent selection during preneoplasia.Nature2023
36993286Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity.bioRxiv2023
37433282Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts.Cancer Cell2023
36050483ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung.Nat Cancer2022
35538268Patient perspectives on window of opportunity clinical trials in early-stage breast cancer.Breast Cancer Res Treat2022
35726067Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer.Nat Genet2022
36400020Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts.Cancer Cell2022
36414627Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.Nat Commun2022
35901781"Fateful" encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression.Dev Cell2022
33467084A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer.Cancers (Basel)2021
33854239The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.Nature2021
33558723Androgen receptor agonists as breast cancer therapeutics.Nat Med2021
33772001The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.Nat Commun2021
34966897Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response.Nat Cancer2021
34497417Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis.Nature2021
34019808A tumor "personality" test to guide therapeutic decision making.Cancer Cell2021
34266469Transcriptome and genome evolution during HER2-amplified breast neoplasia.Breast Cancer Res2021
34009137Cell of Origin Influences Pancreatic Cancer Subtype.Cancer Discov2021
33451982A CRISPR/Cas9-Engineered <i>ARID1A</i>-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation.Cancer Discov2021
32424352Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases.Nat Genet2020
31941752Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism.Mol Cancer Res2020
33157015Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.Mol Cell2020
33203854Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07).Nat Commun2020
32719518Characterizing the ecological and evolutionary dynamics of cancer.Nat Genet2020
32817424The m<sup>6</sup>A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.Proc Natl Acad Sci U S A2020
32587245Looking backward in time to define the chronology of metastasis.Nat Commun2020
32217714Quantifying mutations in healthy blood.Science2020
32238925CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.Nature2020
32401198Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing.Elife2020
30520947Assessment of ERBB2/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines.JAMA Oncol2019
31700186Chromatin regulators mediate anthracycline sensitivity in breast cancer.Nat Med2019
31359002Clonal replacement of tumor-specific T cells following PD-1 blockade.Nat Med2019
31209394Quantitative evidence for early metastatic seeding in colorectal cancer.Nat Genet2019
30867590Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.Nature2019
30737380Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy.Nat Commun2019
31147552Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy.Nat Commun2019
28710260Big Bang Tumor Growth and Clonal Evolution.Cold Spring Harb Perspect Med2018
35135146Tumor Molecular Profiling Aids in Determining Tissue of Origin and Therapy for Metastatic Adenocarcinoma in a Patient With Multiple Primary Malignancies.JCO Precis Oncol2018
29808029Quantification of subclonal selection in cancer from bulk sequencing data.Nat Genet2018
30022114Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data.Nat Genet2018
30177822A role for chromatin regulatory dynamics in breast cancer evolution.Nat Med2018
29903534Harnessing Tumor Evolution to Circumvent Resistance.Trends Genet2018
30361341The chromatin accessibility landscape of primary human cancers.Science2018
29784033AGBT meeting report.Genome Biol2018
29731168Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.Cell2018
29581131Higher Absolute Lymphocyte Counts Predict Lower Mortality from Early-Stage Triple-Negative Breast Cancer.Clin Cancer Res2018
29610476Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.Nat Genet2018
29686366Organoids reveal cancer dynamics.Nature2018
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Collaborators

Carlos Caldas
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 21
Jose A Seoane
Universidade da Coruna
Co-authored papers 19
Simon Tavar??
Irving Institute for Cancer Dynamics, Columbia University
Co-authored papers 13
Samuel Aparicio
University of British Columbia
Co-authored papers 13
Oscar M Rueda
University of Cambridge
Co-authored papers 10
Mark J Dunning
The Medical School, The University of Sheffield
Co-authored papers 9
Andrea Sottoriva
The Institute of Cancer Research, UK Computational Biology Research Centre
Co-authored papers 9
Michael F Press
Co-authored papers 7
Kathleen E Houlahan
University of California los angeles
Co-authored papers 6
Andy G Lynch
University of St Andrews
Co-authored papers 5
Monte M Winslow
Stanford University School of Medicine
Co-authored papers 4
Anne-Lise B??rresen-Dale
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 4
Michael C Bassik
Stanford University Medical Center
Co-authored papers 4
Florian Markowetz
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 4
Hans Kristian Moen Vollan
F Hoffmann-La Roche Ltd
Co-authored papers 3
James M Ford
Stanford University
Co-authored papers 3
Paul D P Pharoah
Center for Cancer Genetic Epidemiology, University of Cambridge
Co-authored papers 3
James D Brenton
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 3
Sohrab P Shah
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Fergus J Couch
Mayo Clinic
Co-authored papers 3
Dennis J Slamon
David Geffen School of Medicine at university of california los angeles
Co-authored papers 3
John C Marioni
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 3
Howard Y Chang
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 3
Stefan Gr??f
Heart and Lung Research Institute, University of Cambridge
Co-authored papers 3
Vessela N Kristensen
Faculty of Clinical Medicine, University of Oslo
Co-authored papers 3
Teri A Longacre
Co-authored papers 3
Dmitri A Petrov
Stanford University
Co-authored papers 2
Adam A Margolin
Icahn School of Medicine
Co-authored papers 2
Kornelia Polyak
Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Martin Hirst
University of British Columbia
Co-authored papers 2
Release 1.2