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Author Details

Enchi Liu
Inc. 0 Shoreline Court
2009
34
23
PMIDPaper TitleJournal TitlePublished Year
37191222A Phase 1 First-in-Human Single-Ascending-Dose Trial With ESB1609, a Selective Agonist to the Sphingosine-1-Phosphate Receptor 5.Clin Pharmacol Drug Dev2023
33836114Differential Inhibition of LRRK2 in Parkinson's Disease Patient Blood by a G2019S Selective LRRK2 Inhibitor.Mov Disord2021
30642435"Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia".Alzheimers Dement2019
29429971Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab.Neurology2018
29914022Long-Term Follow Up of Patients with Mild-to-Moderate Alzheimer's Disease Treated with Bapineuzumab in a Phase III, Open-Label, Extension Study.J Alzheimers Dis2018
30298182Psychometric Evaluation of the Neuropsychological Test Battery in Individuals with Normal Cognition, Mild Cognitive Impairment, or Mild to Moderate Alzheimer's Disease: Results from a Longitudinal Study.J Prev Alzheimers Dis2018
29653606NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.Alzheimers Dement2018
28124589Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer's Disease.Curr Alzheimer Res2017
28386518Outcomes Assessment in Clinical Trials of Alzheimer's Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs.Innov Clin Neurosci2017
25669746Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: a historical, prospective secondary analysis.J Neurol Neurosurg Psychiatry2016
29210443Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Individuals with Early Alzheimer's Disease: Amyloid Imaging Positron Emission Tomography and Safety Results from a Phase 2 Study.J Prev Alzheimers Dis2016
29199321A Randomized, Double-Blind, Phase 2 Study of the Effects of the Vaccine Vanutide Cridificar with QS-21 Adjuvant on Immunogenicity, Safety and Amyloid Imaging in Patients with Mild to Moderate Alzheimer's Disease.J Prev Alzheimers Dis2016
29067308Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor.Alzheimers Dement (N Y)2016
26639957Changes in Brain Volume with Bapineuzumab in Mild to Moderate Alzheimer's Disease.J Alzheimers Dis2016
27589523A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Safety, Pharmacokinetics, and Biomarker Results of Subcutaneous Bapineuzumab in Patients with mild to moderate Alzheimer's disease.J Alzheimers Dis2016
27163805Biomarker Exposure-Response Analysis in Mild-To-Moderate Alzheimer's Disease Trials of Bapineuzumab.J Alzheimers Dis2016
26967206Two Phase 2 Multiple Ascending-Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer's Disease.J Alzheimers Dis2016
26925577First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheimer's disease.Alzheimers Res Ther2016
25708309Building a roadmap for developing combination therapies for Alzheimer's disease.Expert Rev Neurother2015
27239522Revolutionizing Alzheimer's disease and clinical trials through biomarkers.Alzheimers Dement (Amst)2015
26208959Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials.Neurology2015
26194317Perspective: The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partner Scientific Board (PPSB).Alzheimers Dement2015
24092460Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers.Brain Imaging Behav2014
24521259Cognition in MCI and Alzheimer's disease: baseline data from a longitudinal study of the NTB.Clin Neuropsychol2014
24450891Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.N Engl J Med2014
23932184The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.Alzheimers Dement2013
24154646Association between illness progression measures and total cost in Alzheimer's disease.J Nutr Health Aging2013
22047634The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.Alzheimers Dement2012
22473769Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease.Arch Neurol2012
22305802Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis.Lancet Neurol2012
22292124Targeting Beta amyloid: a clinical review of immunotherapeutic approaches in Alzheimer's disease.Int J Alzheimers Dis2012
22343285Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.Proc Natl Acad Sci U S A2012
2018988111C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study.Lancet Neurol2010
19923550A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease.Neurology2009
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Collaborators

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Butler Hospital, and Warren Alpert Medical School of Brown University
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University of California
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Premier Research Institute and NOVA SE University
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Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
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University of California San Francisco
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Mayo Clinic Rochester
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Janssen Pharmaceuticals Research & Development
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Yale University School of Medicine
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