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Author Details

Michael Steffens
Federal Institute for Drugs and Medical Devices (BfArM)
2005
77
32
PMIDPaper TitleJournal TitlePublished Year
34905151Molecular Genetic Techniques in Biomarker Analysis Relevant for Drugs Centrally Approved in Europe.Mol Diagn Ther2022
35923707Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes.Front Genet2022
35102241Evaluation of the EMPAR study population on the basis of metabolic phenotypes of selected pharmacogenes.Pharmacogenomics J2022
34025403CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System-Results From the ADRED Study.Front Pharmacol2021
33516672Fall-Associated Drugs in Community-Dwelling Older Adults: Results from the ActiFE Ulm Study.J Am Med Dir Assoc2021
34012511Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity.Oncotarget2021
34206978Cytogenetic and Biochemical Genetic Techniques for Personalized Drug Therapy in Europe.Diagnostics (Basel)2021
32345696Influence of metabolic profiles on the safety of drug therapy in routine care in Germany: protocol of the cohort study EMPAR.BMJ Open2020
31832731Personalising drug safety-results from the multi-centre prospective observational study on Adverse Drug Reactions in Emergency Departments (ADRED).Eur J Clin Pharmacol2020
32106330Prevalence of Psychotropic Drugs in Cases of Severe Adverse Drug Reactions Leading to Unplanned Emergency Visits in General Hospitals.Pharmacopsychiatry2020
33121145Impact of Zika Virus Infection on Human Neural Stem Cell MicroRNA Signatures.Viruses2020
32612257Citalopram-induced pathways regulation and tentative treatment-outcome-predicting biomarkers in lymphoblastoid cell lines from depression patients.Transl Psychiatry2020
32250457The phenotype of adverse drug effects: Do emergency visits due to adverse drug reactions look different in older people? Results from the ADRED study.Br J Clin Pharmacol2020
32152378Signals of anticipation of reward and of mean reward rates in the human brain.Sci Rep2020
32527038Adverse Drug Reactions in the Emergency Department: Is There a Role for Pharmacogenomic Profiles at Risk?-Results from the ADRED Study.J Clin Med2020
31274544A serotonin transporter polymorphism is associated with postoperative nausea and vomiting: An observational study in two different patient cohorts.Eur J Anaesthesiol2019
31734534Interferon-beta-induced changes in neuroimaging phenotypes of appetitive motivation and reactivity to emotional salience.Neuroimage Clin2019
28747224Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function.Epigenetics Chromatin2017
28456787Predictive blood plasma biomarkers for EGFR inhibitor-induced skin rash.Oncotarget2017
28291260Gene expression and proliferation biomarkers for antidepressant treatment resistance.Transl Psychiatry2017
28669097Medical education in pharmacogenomics-results from a survey on pharmacogenetic knowledge in healthcare professionals within the European pharmacogenomics clinical implementation project Ubiquitous Pharmacogenomics (U-PGx).Eur J Clin Pharmacol2017
27112273Individualized versus standardized risk assessment in patients at high risk for adverse drug reactions (IDrug) - study protocol for a pragmatic randomized controlled trial.BMC Fam Pract2016
26392368Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.Behav Genet2016
27845776Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy.Transl Psychiatry2016
27541716Loss-of-function polymorphisms in the organic cation transporter OCT1 are associated with reduced postoperative tramadol consumption.Pain2016
26820683Dosing to rash?--The role of erlotinib metabolic ratio from patient serum in the search of predictive biomarkers for EGFR inhibitor-mediated skin rash.Eur J Cancer2016
27054571Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample.PLoS One2016
25035082XRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans.Neuropsychopharmacology2015
26419366High-throughput screening identified inherited genetic variations in the EGFR pathway contributing to skin toxicity of EGFR inhibitors.Pharmacogenomics2015
26258132Genetic Geostatistical Framework for Spatial Analysis of Fine-Scale Genetic Heterogeneity in Modern Populations: Results from the KORA Study.Int J Genomics2015
26521924Gene regulatory biomarker identification for skin toxicities induced by EGFR inhibitor treatment.Int J Clin Pharmacol Ther2015
25943212CHL1, ITGB3 and SLC6A4 gene expression and antidepressant drug response: results from the Munich Antidepressant Response Signature (MARS) study.Pharmacogenomics2015
25533491Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study.Lancet Respir Med2015
24857781Cytokine regulation by epidermal growth factor receptor inhibitors and epidermal growth factor receptor inhibitor associated skin toxicity in cancer patients.Eur J Cancer2014
22472876A mega-analysis of genome-wide association studies for major depressive disorder.Mol Psychiatry2013
23933821Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.Nat Genet2013
23739559Familial aggregation of pure tone hearing thresholds in an aging European population.Otol Neurotol2013
23459588αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior.Neuropsychopharmacology2013
23352970Investigation into mechanisms mediating the inhibitory effect of 1,4-benzodiazepines on mast cells by gene expression profiling.Life Sci2013
22921522Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder.J Affect Disord2013
21747397Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe.Mol Psychiatry2012
22949513Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.Hum Mol Genet2012
22944714Cluster-localized sparse logistic regression for SNP data.Stat Appl Genet Mol Biol2012
23010768Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.Transl Psychiatry2012
22874378IT behind a platform for Translational Cancer Research - concept and objectives.Stud Health Technol Inform2012
22004471Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.Addict Biol2012
21353194Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.Am J Hum Genet2011
21521423The German multi-centre study on smoking-related behavior-description of a population-based case-control study.Addict Biol2011
21750470Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype.Pharmacogenet Genomics2011
20023658Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.Nat Genet2010
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Collaborators

Markus M N??then
Institute of Human Genetics, University Hospital Bonn
Co-authored papers 18
Catharina Scholl
Federal Institute for Drugs and Medical Devices (BfArM)
Co-authored papers 16
Sven Cichon
University Hospital Basel and University of Basel
Co-authored papers 16
Stefan Herms
Institute of Human Genetics, University of Bonn
Co-authored papers 14
Marcella Rietschel
Central Institute of Mental Health, University of Mannheim
Co-authored papers 12
Manuel Mattheisen
Dalhousie University
Co-authored papers 11
Wolfgang Maier
University Hospital Bonn
Co-authored papers 11
H-Erich Wichmann
Co-authored papers 11
Per Hoffmann
Institute of Human Genetics, University of Bonn and University Hospital Bonn
Co-authored papers 9
Jens Treutlein
Heidelberg University
Co-authored papers 9
Bertram M??ller-Myhsok
Max Planck Institute of Psychiatry
Co-authored papers 9
Josef Frank
Central Institute of Mental Health, Heidelberg University
Co-authored papers 8
Franziska Degenhardt
University of Duisburg-Essen
Co-authored papers 8
Stefan Schreiber
Co-authored papers 8
Ren?? Breuer
Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University
Co-authored papers 7
Jana Strohmaier
Central Institute of Mental Health, University of Heidelberg
Co-authored papers 6
Thomas G Schulze
SUNY Upstate Medical University
Co-authored papers 6
Thomas W M??hleisen
Institute of Neuroscience and Medicine (INM-1), Research Center Juelich
Co-authored papers 5
Thomas Meitinger
Technical University of Munich, Institute of Human Genetics
Co-authored papers 5
Peter Propping
Instituto de Genetica Humana, Universidad de Bonn
Co-authored papers 5
Matthias Schwab
and of Biochemistry and Pharmacy, University of Tuebingen
Co-authored papers 5
Grant W Montgomery
Co-authored papers 5
Susanne Moebus
Co-authored papers 5
Nicholas G Martin
Co-authored papers 5
Nick Craddock
Co-authored papers 4
Michael C O'Donovan
Co-authored papers 4
Jeroen R Huyghe
Co-authored papers 4
Kerstin U Ludwig
Institute of Human Genetics, University of Bonn
Co-authored papers 4
Peter Lichtner
Co-authored papers 4
Christian Gieger
German Research Center for Cardiovascular Disease (DZHK)
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Release 1.2