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Author Details

Stephen N Floor
University of California san francisco
2001
37
19
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37314931Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression.Cell Rep2023
37808656Nucleolar dynamics are determined by the ordered assembly of the ribosome.bioRxiv2023
37857907RNA molecular recording with an engineered RNA deaminase.Nat Methods2023
37857833A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response.Nat Cell Biol2023
37745530Determinants of DDX3X sensitivity uncovered using a helicase activity in translation reporter.bioRxiv2023
37674086Dynamic regulation of messenger RNA structure controls translation.Nature2023
37422363The variant landscape and function of DDX3X in cancer and neurodevelopmental disorders.Trends Mol Med2023
37214951A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X.bioRxiv2023
35202586SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal.Dev Cell2022
35965005Lysate and cell-based assays to probe the translational role of RNA helicases.Methods Enzymol2022
35015630Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.Elife2022
33296667Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A.Cell Chem Biol2021
33905506DDX3 depletion represses translation of mRNAs with complex 5' UTRs.Nucleic Acids Res2021
33622983Control of ribosomal protein synthesis by the Microprocessor complex.Sci Signal2021
32135084Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development.Neuron2020
32353859A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.Nature2020
30595437The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.Mol Cell2019
31263002<i>PTBP1</i> mRNA isoforms and regulation of their translation.RNA2019
29677487The Traffic Jam: Polyamine Prevalence Pauses Protein Production.Mol Cell2018
30054595CRISPR-Cas9 genome editing in human cells occurs via the Fanconi anemia pathway.Nat Genet2018
31021197Move Over, Genomes: Here Comes Transcriptome Engineering.CRISPR J2018
29141229Widespread Translational Remodeling during Human Neuronal Differentiation.Cell Rep2017
28191903Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.Nat Biotechnol2017
27058758Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.Oncotarget2016
26598523Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.J Biol Chem2016
26650549Analog sensitive chemical inhibition of the DEAD-box protein DDX3.Protein Sci2016
27309803Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor.Nature2016
26735365Tunable protein synthesis by transcript isoforms in human cells.Elife2016
26638173Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome.Mol Cell2015
23911090Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2.Structure2013
22323607Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.Proc Natl Acad Sci U S A2012
20711189A split active site couples cap recognition by Dcp2 to activation.Nat Struct Mol Biol2010
18280238mRNA decapping is promoted by an RNA-binding channel in Dcp2.Mol Cell2008
19172744SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction.Nat Struct Mol Biol2008
18998650Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.J Am Chem Soc2008
18971632Control of mRNA decapping by Dcp2: An open and shut case?RNA Biol2008
11690269Empirical investigation of extreme single-particle behavior of nuclear quadrupole moments in highly collective A approximately 150 superdeformed bands.Phys Rev Lett2001
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Collaborators

John D Gross
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 8
Srivats Venkataramanan
Management and Science University
Co-authored papers 7
Jennifer A Doudna
Innovative Genomics Institute, University of California berkeley
Co-authored papers 7
Lorenzo Calviello
Functional Genomics Research Centre, Italy Computational Biology Research Centre
Co-authored papers 5
Danica Galoni?? Fujimori
University of California San Francisco
Co-authored papers 2
Shaeri Mukherjee
G.W. Hooper Foundation, University of California at San Francisco
Co-authored papers 2
Danielle L Swaney
J. David Gladstone Institutes
Co-authored papers 2
James S Fraser
University of California san francisco
Co-authored papers 2
Elliott H Sherr
Co-authored papers 2
Peter Walter
University of California san francisco
Co-authored papers 2
Kevan M Shokat
University of California San Francisco
Co-authored papers 2
Advait Subramanian
University of California san francisco
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Danish Memon
European Bioinformatics Institute
Co-authored papers 1
Mathieu Hubert
Institut Pasteur
Co-authored papers 1
Melanie J Bennett
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Djoshkun Shengjuler
Institut Pasteur
Co-authored papers 1
Hannes Braberg
University of California San Francisco
Co-authored papers 1
Yiming Cai
Institute of Mental Health and Woodbridge Hospital
Co-authored papers 1
Barbara Celona
Cardiovascular Research Institute, University of California san francisco
Co-authored papers 1
Alan D Frankel
University of California san francisco
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Eric Verdin
Buck Institute for Research on Aging
Co-authored papers 1
Davide Ruggero
University of California San Francisco
Co-authored papers 1
Ying Shi
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences
Co-authored papers 1
Phillip P Sharp
University of California san francisco
Co-authored papers 1
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Marie-Laure Yaspo
Max Planck Institute for Molecular Genetics
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Eric W Klee
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Jiewei Xu
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Release 1.2