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Author Details

Pamela Metten
Portland Alcohol Research Center, Oregon Health & Science University
1993
71
30
PMIDPaper TitleJournal TitlePublished Year
36656645Preclinical and clinical evidence for suppression of alcohol intake by apremilast.J Clin Invest2023
34227188Long-term alcohol drinking in High Drinking in the Dark mice is stable for many months and does not show alcohol deprivation effects.Addict Biol2022
36001437Midazolam, methamphetamine, morphine and nicotine intake in high-drinking-in-the-dark mice.Addict Biol2022
36198764Genetic and genomic signatures in ethanol withdrawal seizure-prone and seizure-resistant mice implicate genes involved in epilepsy and neuronal excitability.Mol Psychiatry2022
33556460The impact of Drinking in the Dark (DID) procedural manipulations on ethanol intake in High Drinking in the Dark (HDID) mice.Alcohol2021
33557285Ethanol-Related Behaviors in Mouse Lines Selectively Bred for Drinking to Intoxication.Brain Sci2021
32154593Targeting the Glucocorticoid Receptor Reduces Binge-Like Drinking in High Drinking in the Dark (HDID-1) Mice.Alcohol Clin Exp Res2020
34589846Tetracycline derivatives reduce binge alcohol consumption in High Drinking in the Dark mice.Brain Behav Immun Health2020
31853996Effects of Pharmacologically Targeting Neuroimmune Pathways on Alcohol Drinking in Mice Selectively Bred to Drink to Intoxication.Alcohol Clin Exp Res2020
33294845Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice.Neurosci Insights2020
30609665Ethanol Conditioned Taste Aversion in High Drinking in the Dark Mice.Brain Sci2019
29251283Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice.Neuropsychopharmacology2018
29427828An alcohol withdrawal test battery measuring multiple behavioral symptoms in mice.Alcohol2018
29786871Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs.Alcohol Clin Exp Res2018
28827047High Drinking in the Dark (HDID) mice are sensitive to the effects of some clinically relevant drugs to reduce binge-like drinking.Pharmacol Biochem Behav2017
28442218Alignment of the transcriptome with individual variation in animals selectively bred for High Drinking-In-the-Dark (HDID).Alcohol2017
26795092Nest building is a novel method for indexing severity of alcohol withdrawal in mice.Behav Brain Res2016
27139234Fear conditioning in mouse lines genetically selected for binge-like ethanol drinking.Alcohol2016
24219304Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice.Genes Brain Behav2014
25581648Dual-trait selection for ethanol consumption and withdrawal: genetic and transcriptional network effects.Alcohol Clin Exp Res2014
24923803Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.Genetics2014
24612020Genetic relationship between predisposition for binge alcohol consumption and blunted sensitivity to adverse effects of alcohol in mice.Alcohol Clin Exp Res2014
23550792Selection for drinking in the dark alters brain gene coexpression networks.Alcohol Clin Exp Res2013
23809872Ethanol drinking in withdrawal seizure-prone and -resistant selected mouse lines.Alcohol2013
21947288Ethanol withdrawal-induced motor impairment in mice.Psychopharmacology (Berl)2012
24533180Ethanol Withdrawal-Associated Drinking and Drinking in the Dark: Common and Discrete Genetic Contributions.Addict Genet2012
22717273Intermittent availability of ethanol does not always lead to elevated drinking in mice.Alcohol Alcohol2012
22309139Ethanol tolerance and withdrawal severity in high drinking in the dark selectively bred mice.Alcohol Clin Exp Res2012
22316249Ethanol sensitivity in high drinking in the dark selectively bred mice.Alcohol Clin Exp Res2012
22432643Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.Alcohol Clin Exp Res2012
21194877Alcohol preference drinking in a mouse line selectively bred for high drinking in the dark.Alcohol2011
21238474Limited access ethanol drinking in the dark in adolescent and adult mice.Pharmacol Biochem Behav2011
20586758Withdrawal severity after chronic intermittent ethanol in inbred mouse strains.Alcohol Clin Exp Res2010
19041892Calibration of rotational acceleration for the rotarod test of rodent motor coordination.J Neurosci Methods2009
19587272Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism.J Neurosci2009
19095222A line of mice selected for high blood ethanol concentrations shows drinking in the dark to intoxication.Biol Psychiatry2009
18774238Genetic correlates of morphine withdrawal in 14 inbred mouse strains.Drug Alcohol Depend2009
18690115Motor impairment: a new ethanol withdrawal phenotype in mice.Behav Pharmacol2008
18774184Multivariate analyses reveal common and drug-specific genetic influences on responses to four drugs of abuse.Trends Pharmacol Sci2008
17226103Use of a novel mouse genotype to model acute benzodiazepine withdrawal.Behav Genet2007
16619134Effects of genetic and procedural variation on measurement of alcohol sensitivity in mouse inbred strains.Behav Genet2006
16436183Fine mapping of a sedative-hypnotic drug withdrawal locus on mouse chromosome 11.Genes Brain Behav2006
15642621An analysis of the genetics of alcohol intoxication in inbred mice.Neurosci Biobehav Rev2005
16187819Alcohol withdrawal severity in inbred mouse (Mus musculus) strains.Behav Neurosci2005
16340451Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice.Alcohol Clin Exp Res2005
16099022Scheduled access to ethanol results in motor impairment and tolerance in female C57BL/6J mice.Pharmacol Biochem Behav2005
15033960Observer-rated ataxia: rating scales for assessment of genetic differences in ethanol-induced intoxication in mice.J Appl Physiol (1985)2004
14960011Potential pleiotropic effects of Mpdz on vulnerability to seizures.Genes Brain Behav2004
15120579Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs.Brain Res2004
12486710Different data from different labs: lessons from studies of gene-environment interaction.J Neurobiol2003
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Collaborators

John C Crabbe
Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 71
John K Belknap
Oregon Health & Science University
Co-authored papers 17
Jason P Schlumbohm
Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 17
Stephanie E Spence
Oregon Health & Science University
Co-authored papers 14
Kari J Buck
Oregon Health & Science University
Co-authored papers 11
Tamara J Phillips
Oregon Health & Science University
Co-authored papers 8
Robert Hitzemann
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 5
Ovidiu D Iancu
Oregon Health & Science University
Co-authored papers 4
Denesa Oberbeck
Oregon Health & Science University
Co-authored papers 4
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 4
Alexandre Colville
Oregon Health & Science University
Co-authored papers 4
Kolter B Grigsby
University of Missouri
Co-authored papers 3
Priscila Darakjian
Oregon National Primate Research Center
Co-authored papers 3
Amanda J Roberts
The Scripps Research Institute
Co-authored papers 2
Hiroshi Ohno
RIKEN Center for Integrative Medical Sciences
Co-authored papers 1
Nicole A R Walter
Oregon National Primate Research Center, Oregon Health & Science University
Co-authored papers 1
Christina L Zheng
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Robert P Searles
Oregon Health & Science University
Co-authored papers 1
Chris Downing
Institute for Behavioral Genetics, University of Colorado
Co-authored papers 1
Sunita Kawane
Clinical & Translational Research Institute, Oregon Health and Science University
Co-authored papers 1
Beth Wilmot
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Roy Dayne Mayfield
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin
Co-authored papers 1
Sue Burkhart-Kasch
Co-authored papers 1
Christina A Harrington
Oregon Health & Science University
Co-authored papers 1
Robert Plomin
Co-authored papers 1
Carrie S McKinnon
Co-authored papers 1
Laura B Ferguson
Co-authored papers 1
Elissa J Chesler
Center for Systems Neurogenetics of Addiction at The Jackson Laboratory
Co-authored papers 1
David Goldman
Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism.
Co-authored papers 1
Marcelo F Lopez
Charleston Alcohol Research Center, Medical University of South Carolina
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Release 1.2