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| 37556795 | SETDB1 Triple Tudor Domain Ligand, (<i>R</i>,<i>R</i>)-59, Promotes Methylation of Akt1 in Cells. | ACS Chem Biol | 2023 |
| 37549269 | SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1. | Proc Natl Acad Sci U S A | 2023 |
| 37600767 | The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population. | Front Immunol | 2023 |
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| 37214894 | SETDB1 Triple Tudor Domain Ligand, ( <i>R,R</i> )-59, Promotes Methylation of Akt1 in Cells. | bioRxiv | 2023 |
| 36976643 | Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2. | J Am Chem Soc | 2023 |
| 37360399 | Target 2035 - an update on private sector contributions. | RSC Med Chem | 2023 |
| 36858798 | RAS and PP2A activities converge on epigenetic gene regulation. | Life Sci Alliance | 2023 |
| 36651994 | Detection of antibodies against the huntingtin protein in human plasma. | Cell Mol Life Sci | 2023 |
| 36802665 | Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21. | J Med Chem | 2023 |
| 36732527 | Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei. | Nat Commun | 2023 |
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| 35676539 | Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation. | Nat Chem Biol | 2022 |
| 35578032 | PRMT inhibition induces a viral mimicry response in triple-negative breast cancer. | Nat Chem Biol | 2022 |
| 35363509 | Validating Small Molecule Chemical Probes for Biological Discovery. | Annu Rev Biochem | 2022 |
| 35783295 | CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding. | Nat Rev Chem | 2022 |
| 35907431 | Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro. | Biochim Biophys Acta Gene Regul Mech | 2022 |
| 36192397 | De novo design of immunoglobulin-like domains. | Nat Commun | 2022 |
| 36288699 | Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease. | Cell Rep | 2022 |
| 36191185 | Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation. | Proc Natl Acad Sci U S A | 2022 |
| 36084291 | Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes. | ACS Chem Biol | 2022 |
| 35244724 | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. | Nucleic Acids Res | 2022 |
| 34936354 | Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence. | J Chem Theory Comput | 2022 |
| 34958585 | Correction to "Structure-Activity Relationship of USP5 Inhibitors". | J Med Chem | 2022 |
| 33980013 | Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. | J Med Chem | 2021 |
| 33522809 | Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2. | J Med Chem | 2021 |
| 33742187 | Protein arginine methylation: from enigmatic functions to therapeutic targeting. | Nat Rev Drug Discov | 2021 |
| 33575256 | A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation. | Front Cell Dev Biol | 2021 |
| 33513288 | Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics*. | ChemMedChem | 2021 |
| 33591753 | A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6. | J Med Chem | 2021 |
| 33529165 | RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors. | J Clin Invest | 2021 |
| 33579912 | PRMT5 inhibition disrupts splicing and stemness in glioblastoma. | Nat Commun | 2021 |
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| 34648286 | Structure-Activity Relationship of USP5 Inhibitors. | J Med Chem | 2021 |
| 34662547 | Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells. | J Mol Biol | 2021 |
| 34718722 | The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface. | Nucleic Acids Res | 2021 |
| 34188192 | MYC protein interactors in gene transcription and cancer. | Nat Rev Cancer | 2021 |
| 34019286 | Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies. | Methods Mol Biol | 2021 |
| 34154424 | Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. | SLAS Discov | 2021 |
| 32367723 | Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor. | J Med Chem | 2020 |
| 33054974 | Correction: A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion. | Elife | 2020 |
| 33090784 | Epigenetics 2.0: Special Issue on Epigenetics-Call for Papers. | J Med Chem | 2020 |
| 32609811 | Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. | Nucleic Acids Res | 2020 |
| 32917713 | LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. | Sci Adv | 2020 |
| 32445698 | Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. | Cell | 2020 |
| 32546577 | Epigenetic Switch-Induced Viral Mimicry Evasion in Chemotherapy-Resistant Breast Cancer. | Cancer Discov | 2020 |