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Author Details

Otto Valladares
2000
45
29
PMIDPaper TitleJournal TitlePublished Year
37881831NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge.Alzheimers Dement2024
37162864hipFG: High-throughput harmonization and integration pipeline for functional genomics data.2023
37947320hipFG: high-throughput harmonization and integration pipeline for functional genomics data.2023
37461624Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies <i>LRRC4C, LHX5-AS1</i> and nominates ancestry-specific loci <i>PTPRK</i> , <i>GRB14</i> , and <i>KIAA0825</i> as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.medRxiv2023
35068457Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.Journal of Alzheimer's Disease2022
35379992New insights into the genetic etiology of Alzheimer's disease and related dementias.Nat Genet2022
35047815FILER: a framework for harmonizing and querying large-scale functional genomics knowledge.NAR Genomics and Bioinformatics2022
34873149Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.Transl Psychiatry2021
34804120Copy Number Variation Identification on 3,800 Alzheimer's Disease Whole Genome Sequencing Data from the Alzheimer's Disease Sequencing Project.Frontiers in Genetics2021
32270138HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions.NAR Genomics and Bioinformatics2020
32330239SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants.2020
30668832DASHR 2.0: integrated database of human small non-coding RNA genes and mature products.2019
30351394VCPA: genomic variant calling pipeline and data management tool for Alzheimer's Disease Sequencing Project.2019
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
29733404SPAR: small RNA-seq portal for analysis of sequencing experiments.Nucleic Acids Research2018
30113658INFERNO: inferring the molecular mechanisms of noncoding genetic variants.Nucleic Acids Research2018
28714976Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Nat Genet2017
26553799DASHR: database of small human noncoding RNAs.Nucleic Acids Res2016
25778476A novel Alzheimer disease locus located near the gene encoding tau protein.Mol Psychiatry2016
26092349Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.Alzheimers Dement2016
26366463Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.JAMA Neurol2015
25531812Rarity of the Alzheimer disease-protective APP A673T variant in the United States.JAMA Neurol2015
25480377HIPPIE: a high-throughput identification pipeline for promoter interacting enhancer elements.2015
25470345Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.J Neuropathol Exp Neurol2015
25936935The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease.Alzheimers Dement2015
24922517Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.PLoS One2014
25363760Synaptic, transcriptional and chromatin genes disrupted in autism.Nature2014
24770881ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.Acta Neuropathol2014
25199842Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.JAMA Neurol2014
23571587Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.JAMA2013
24162737Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.Nat Genet2013
23943636DRAW+SneakPeek: analysis workflow and quality metric management for DNA-seq experiments.2013
24149843HAMR: high-throughput annotation of modified ribonucleotides.RNA2013
23352160Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.Neuron2013
22492627SAVoR: a server for sequencing annotation and visualization of RNA structures.Nucleic Acids Research2012
22495311Patterns and rates of exonic de novo mutations in autism spectrum disorders.Nature2012
22832108Global analysis of RNA secondary structure in two metazoans.Cell Rep2012
20941385Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis.PLoS Genetics2010
20041592Sleep behaviors and sleep quality in children with autism spectrum disorders.Sleep2009
18028544Genome-wide expression profiling and bioinformatics analysis of diurnally regulated genes in the mouse prefrontal cortex.Genome Biol2007
17096848Patterns of sequence conservation in presynaptic neural genes.Genome Biol2006
12874602alpha 1d Adrenoceptor signaling is required for stimulus induced locomotor activity.Molecular Psychiatry2003
12244319Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse.Nat Genet2002
11389854A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle.Molecular Cell2001
11145318An automated system for recording and analysis of sleep in mice.Sleep2000
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