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Author Details

Johanna Ten Hoeve
California Nanosystems Institute, University of California los angeles
1990
33
23
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37279645M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance.Neuro Oncol2023
38014170Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas.bioRxiv2023
37923961A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.Commun Biol2023
34813507Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.J Clin Invest2022
36396639Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas.Nat Commun2022
36137002Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function.PLoS Biol2022
36306790The m<sup>6</sup>A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia.Cancer Cell2022
34930786Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.Cancer Discov2022
33284134Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity.JCI Insight2021
34019840Adhesion-mediated mechanosignaling forces mitohormesis.Cell Metab2021
34031590Mitohormesis reprogrammes macrophage metabolism to enforce tolerance.Nat Metab2021
33434505R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m<sup>6</sup>A/PFKP/LDHB axis.Mol Cell2021
32219444Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia.Blood2020
32859923Defining the ATPome reveals cross-optimization of metabolic pathways.Nat Commun2020
31160601Ampk regulates IgD expression but not energy stress with B cell activation.Sci Rep2019
31484989Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy.Sci Rep2019
28202506Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.Mol Syst Biol2017
27648299JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma.Cell Discov2016
15753310Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle.Proc Natl Acad Sci U S A2005
16014513DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling.Development2005
12138178Identification of a nuclear Stat1 protein tyrosine phosphatase.Mol Cell Biol2002
11248056A transcriptional corepressor of Stat1 with an essential LXXLL signature motif.Proc Natl Acad Sci U S A2001
9053848Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site.Oncogene1997
8710363Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia.Oncogene1996
7545163Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia.J Biol Chem1995
8666394Localization of the human mitochondrial citrate transporter protein gene to chromosome 22Q11 in the DiGeorge syndrome critical region.Genomics1995
7521685Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.Blood1994
8013387Negative cooperativity in the insulin-like growth factor-I receptor and a chimeric IGF-I/insulin receptor.Endocrinology1994
8168080Cellular interactions of CRKL, and SH2-SH3 adaptor protein.Cancer Res1994
7905853Isolation of NotI sites from chromosome 22q11.Genomics1993
8361759Isolation and chromosomal localization of CRKL, a human crk-like gene.Oncogene1993
8095916Localization of a gamma-glutamyl-transferase-related gene family on chromosome 22.Hum Genet1993
2179728Acute leukaemia in bcr/abl transgenic mice.Nature1990
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Collaborators

Matteo Pellegrini
Co-authored papers 3
Aldons J Lusis
Co-authored papers 3
Daniel K Nomura
University of California berkeley
Co-authored papers 2
Kevin M Tharp
University of California berkeley
Co-authored papers 2
Orian S Shirihai
David Geffen School of Medicine (L.S., University of California los angeles
Co-authored papers 2
Breanna Ford
University of California berkeley
Co-authored papers 2
Greg A Timblin
University of California Berkeley
Co-authored papers 2
Amelia Palermo
Co-authored papers 2
Jonathon M Muncie
Gladstone Institutes
Co-authored papers 1
Jens Luebeck
University of California San Diego
Co-authored papers 1
Marc K Hellerstein
University of California berkeley
Co-authored papers 1
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 1
Jan Willem Voncken
Maastricht University
Co-authored papers 1
Alan S Wayne
Cancer and Blood Disease Institute, Children's Hospital Los Angeles
Co-authored papers 1
Joseph R Daniele
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Stefan Homentcovschi
Howard Hughes Medical Institute, University of California Berkeley
Co-authored papers 1
Matthew J Oberley
Co-authored papers 1
Alicia L Richards
University of Wisconsin-Madison
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Hao Shao
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 1
Gabriel Karin
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Costas A Lyssiotis
Co-authored papers 1
Vineet Bafna
University of California San Diego
Co-authored papers 1
Laurent Vergnes
Co-authored papers 1
Andrew S Moore
Howard Hughes Medical Institute
Co-authored papers 1
Valerie M Weaver
University of California san francisco
Co-authored papers 1
Yonggang Zhou
David Geffen School of Medicine, University of California at Los Angeles
Co-authored papers 1
Michel L Tremblay
Co-authored papers 1
Bjoern Titz
university of california los angeles
Co-authored papers 1
Andrew Dillin
Howard Hughes Medical Institute, The University of California berkeley
Co-authored papers 1
Guido Jenster
Erasmus University Medical Center
Co-authored papers 1
Release 1.2