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Author Details

Hai Fang
University of Bristol
2006
67
27
PMIDPaper TitleJournal TitlePublished Year
36686803When cancer drug resistance meets metabolomics (bulk, single-cell and/or spatial): Progress, potential, and perspective.Front Oncol2023
37638009Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level.Front Immunol2023
37061086The dcGO Domain-Centric Ontology Database in 2023: New Website and Extended Annotations for Protein Structural Domains.J Mol Biol2023
37158276OpenXGR: a web-server update for genomic summary data interpretation.Nucleic Acids Res2023
37388915Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis.Cell Genom2023
37285660Priority index for asthma (PIA): In silico discovery of shared and distinct drug targets for adult- and childhood-onset disease.Comput Biol Med2023
37283746Editorial: Translational phenomics and its applications in immunotherapy.Front Immunol2023
36808136Hypothesis-free phenotype prediction within a genetics-first framework.Nat Commun2023
34751399Priority index: database of genetic targets in immune-mediated disease.Nucleic Acids Res2022
35610036PiER: web-based facilities tailored for genetic target prioritisation harnessing human disease genetics, functional genomics and protein interactions.Nucleic Acids Res2022
35401535Genomic Evidence Supports the Recognition of Endometriosis as an Inflammatory Systemic Disease and Reveals Disease-Specific Therapeutic Potentials of Targeting Neutrophil Degranulation.Front Immunol2022
35751107Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance.Genome Biol2022
35385357Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases.Proc Natl Acad Sci U S A2022
36442087Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.Proc Natl Acad Sci U S A2022
35863823Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities.J Immunother Cancer2022
36344675Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation.Oncogene2022
32854112A PML/RARα direct target atlas redefines transcriptional deregulation in acute promyelocytic leukemia.Blood2021
33733367Genetic Interaction Network Interpretation: A Tidy Data Science Perspective.Methods Mol Biol2021
33893160Integration of Genomic and Transcriptomic Markers Improves the Prognosis Prediction of Acute Promyelocytic Leukemia.Clin Cancer Res2021
33746983Transcriptomic Analysis of Inflammatory Cardiomyopathy Identifies Molecular Signatures of Disease and Informs <i>in silico</i> Prediction of a Network-Based Rationale for Therapy.Front Immunol2021
34489936Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.Front Immunol2021
34839264Identification of copy number variation-driven molecular subtypes informative for prognosis and treatment in pancreatic adenocarcinoma of a Chinese cohort.EBioMedicine2021
34561618Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2<sup>pos</sup> subjects.Cell Res2021
34103487Integrating longitudinal clinical laboratory tests with targeted proteomic and transcriptomic analyses reveal the landscape of host responses in COVID-19.Cell Discov2021
34279044Genomic Insights into Myasthenia Gravis Identify Distinct Immunological Mechanisms in Early and Late Onset Disease.Ann Neurol2021
32759223Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300.Proc Natl Acad Sci U S A2020
32042196Peripheral CD8<sup>+</sup> T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma.Nat Med2020
31253980A genetics-led approach defines the drug target landscape of 30 immune-related traits.Nat Genet2019
31744546The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.Genome Biol2019
31765831I3: A Self-organising Learning Workflow for Intuitive Integrative Interpretation of Complex Genetic Data.Genomics Proteomics Bioinformatics2019
31260048The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis.Hum Reprod Update2019
30428322Regulatory Genomic Data Cubism.iScience2018
29142230Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.Nat Commun2017
26780608A predictive computational framework for direct reprogramming between human cell types.Nat Genet2016
26546158Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia.Blood2016
27604469An expanded evaluation of protein function prediction methods shows an improvement in accuracy.Genome Biol2016
27964755XGR software for enhanced interpretation of genomic summary data, illustrated by application to immunological traits.Genome Med2016
27358427Evolution of the Calcium-Based Intracellular Signaling System.Genome Biol Evol2016
25339269A proteome quality index.Environ Microbiol2015
25980317Function-selective domain architecture plasticity potentials in eukaryotic genome evolution.Biochimie2015
25414345The SUPERFAMILY 1.75 database in 2014: a doubling of data.Nucleic Acids Res2015
24309102supraHex: an R/Bioconductor package for tabular omics data analysis using a supra-hexagonal map.Biochem Biophys Res Commun2014
27358859Reactive oxygen species in eradicating acute myeloid leukemic stem cells.Stem Cell Investig2014
25246945The 'dnet' approach promotes emerging research on cancer patient survival.Genome Med2014
25371902A derived network-based interferon-related signature of human macrophages responding to Mycobacterium tuberculosis.Biomed Res Int2014
25356683dcGOR: an R package for analysing ontologies and protein domain annotations.PLoS Comput Biol2014
25182274Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy.Nat Commun2014
24670764A promoter-level mammalian expression atlas.Nature2014
24692656The evolution of human cells in terms of protein innovation.Mol Biol Evol2014
23353650A large-scale evaluation of computational protein function prediction.Nat Methods2013
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Collaborators

Julian Gough
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 20
Ji Zhang
Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine
Co-authored papers 12
Julian C Knight
University of Oxford
Co-authored papers 11
Matt E Oates
University of Bristol
Co-authored papers 9
Zhu Chen
Yong Loo Lin School of Medicine, National University of Singapore
Co-authored papers 8
Owen J L Rackham
Duke-National University of Singapore
Co-authored papers 8
Yanzhi Du
Center for Reproductive Medicine, Ren Ji Hospital, Shanghai Jiao Tong University
Co-authored papers 6
Ben Smithers
University of Bristol
Co-authored papers 5
Natalie Thurlby
University of Bristol
Co-authored papers 4
Prajwal Bhat
Royal Holloway University of London
Co-authored papers 3
Marco Falda
University of Padova
Co-authored papers 3
Alfonso E Romero
University of Miami
Co-authored papers 3
Enrico Lavezzo
University of Padova
Co-authored papers 3
Paolo Fontana
San Pio Hospital
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Predrag Radivojac
Indiana University
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Fran Supek
Catalan Institution for Research and Advanced Studies (ICREA)
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Haixuan Yang
University of Galway
Co-authored papers 3
Sean D Mooney
University of Washington
Co-authored papers 3
Stefano Toppo
University of Padova
Co-authored papers 3
Patricia C Babbitt
University of California san francisco
Co-authored papers 3
Asa Ben-Hur
Colorado State University
Co-authored papers 3
Michal Linial
Institute of Life Sciences, The Hebrew University of Jerusalem
Co-authored papers 3
Daisuke Kihara
Purdue University
Co-authored papers 3
Iddo Friedberg
Iowa State University
Co-authored papers 3
David T Jones
University College London
Co-authored papers 3
Steven E Brenner
University of California berkeley
Co-authored papers 3
Rita Casadio
Department of Pharmacy and Biotechnology, University of Bologna
Co-authored papers 3
Burkhard Rost
Technical University of Munich (TUM)
Co-authored papers 3
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Domenico Cozzetto
Imperial College London
Co-authored papers 3
Release 1.2