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Author Details

Udo Rudloff
Center for Cancer Research, National Cancer Institute
1994
77
23
PMIDPaper TitleJournal TitlePublished Year
36790955Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling.Mol Cancer Res2023
37196527Determination of metarrestin (ML-246) in human plasma for a first-in-human clinical pharmacokinetic application by a simple and efficient uHPLC-MS/MS assay.J Chromatogr B Analyt Technol Biomed Life Sci2023
37190294Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies.Cancers (Basel)2023
37174654A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice.Cells2023
36790955Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling.Mol Cancer Res2023
37190294Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies.Cancers (Basel)2023
37174654A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice.Cells2023
37196527Determination of metarrestin (ML-246) in human plasma for a first-in-human clinical pharmacokinetic application by a simple and efficient uHPLC-MS/MS assay.J Chromatogr B Analyt Technol Biomed Life Sci2023
36250721Emerging kinase inhibitors for the treatment of pancreatic ductal adenocarcinoma.Expert Opin Emerg Drugs2022
36250721Emerging kinase inhibitors for the treatment of pancreatic ductal adenocarcinoma.Expert Opin Emerg Drugs2022
35754433Teaching principles of translational science to a broad scientific audience using a case study approach: A pilot course from the National Center for Advancing Translational Sciences.J Clin Transl Sci2022
35696646Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.J Med Chem2022
35696646Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.J Med Chem2022
35754433Teaching principles of translational science to a broad scientific audience using a case study approach: A pilot course from the National Center for Advancing Translational Sciences.J Clin Transl Sci2022
33405090Phase II study of selumetinib, an orally active inhibitor of MEK1 and MEK2 kinases, in KRAS<sup>G12R</sup>-mutant pancreatic ductal adenocarcinoma.Invest New Drugs2021
34079928Mini-Review: PDPK1 (3-phosphoinositide dependent protein kinase-1), An Emerging Cancer Stem Cell Target.J Cancer Treatment Diagn2021
33405090Phase II study of selumetinib, an orally active inhibitor of MEK1 and MEK2 kinases, in KRAS<sup>G12R</sup>-mutant pancreatic ductal adenocarcinoma.Invest New Drugs2021
34376576T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer.Mol Cancer Ther2021
34376576T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer.Mol Cancer Ther2021
34079928Mini-Review: PDPK1 (3-phosphoinositide dependent protein kinase-1), An Emerging Cancer Stem Cell Target.J Cancer Treatment Diagn2021
32185484Metabolism and pharmacokinetics characterization of metarrestin in multiple species.Cancer Chemother Pharmacol2020
31649109Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.Cancer Discov2020
32185484Metabolism and pharmacokinetics characterization of metarrestin in multiple species.Cancer Chemother Pharmacol2020
32051227Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.Sci Transl Med2020
31931447LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies.J Pharm Biomed Anal2020
32766584A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice.bioRxiv2020
32619635Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cells.Regul Toxicol Pharmacol2020
31931447LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies.J Pharm Biomed Anal2020
32051227Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.Sci Transl Med2020
31649109Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.Cancer Discov2020
32766584A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice.bioRxiv2020
32619635Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cells.Regul Toxicol Pharmacol2020
30745422Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC).J Med Genet2019
30745422Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC).J Med Genet2019
31395684Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.Mol Cancer Ther2019
31395684Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.Mol Cancer Ther2019
29214884Adjuvant intraperitoneal chemotherapy for the treatment of colorectal cancer at risk for peritoneal carcinomatosis: a systematic review.Int J Hyperthermia2018
30306263Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras[G12D/+];Tp53[R172H/+] (KPC) mice, a genetically engineered model of pancreatic cancer.Cancer Chemother Pharmacol2018
30064387Loss of PDPK1 abrogates resistance to gemcitabine in label-retaining pancreatic cancer cells.BMC Cancer2018
30584346Gastric adenocarcinoma and proximal polyposis of the stomach: diagnosis and clinical perspectives.Clin Exp Gastroenterol2018
29214884Adjuvant intraperitoneal chemotherapy for the treatment of colorectal cancer at risk for peritoneal carcinomatosis: a systematic review.Int J Hyperthermia2018
29468433Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk.Clin Transl Med2018
29769289Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.Sci Transl Med2018
29145578The Changing Paradigm of Management of Liver Abscesses in Chronic Granulomatous Disease.Clin Infect Dis2018
30064387Loss of PDPK1 abrogates resistance to gemcitabine in label-retaining pancreatic cancer cells.BMC Cancer2018
30306263Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras[G12D/+];Tp53[R172H/+] (KPC) mice, a genetically engineered model of pancreatic cancer.Cancer Chemother Pharmacol2018
30584346Gastric adenocarcinoma and proximal polyposis of the stomach: diagnosis and clinical perspectives.Clin Exp Gastroenterol2018
29468433Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk.Clin Transl Med2018
29769289Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.Sci Transl Med2018
29145578The Changing Paradigm of Management of Liver Abscesses in Chronic Granulomatous Disease.Clin Infect Dis2018
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Collaborators

Goldman School of Medicine, Ben Gurion University
Co-authored papers 15
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 8
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 7
Co-authored papers 7
David Geffen School of Medicine, University of California los angeles
Co-authored papers 5
Center for Cancer Research, National Cancer Institute
Co-authored papers 5
National Institute of Diabetes and Digestive and Kidney Diseases
Co-authored papers 5
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Clinical Research Section
Co-authored papers 4
University of Washington
Co-authored papers 4
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 4
Weizmann Institute of Science
Co-authored papers 4
Lawrence Livermore National Laboratory
Co-authored papers 4
University of Colorado School of Medicine
Co-authored papers 3
National Cancer Institute (NCI), National Institutes of Health (NIH)
Co-authored papers 3
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
National Cancer Institute
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
INSERM U, PSL Research University, Institut Curie Research Center
Co-authored papers 2
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
Co-authored papers 2
Co-authored papers 2
National Institute of Allergy and Infectious Diseases
Co-authored papers 2
From Foundation Medicine
Co-authored papers 2
Vertex Pharmaceuticals
Co-authored papers 2
Institute of Pathology, Heidelberg University Hospital
Co-authored papers 2
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Co-authored papers 2
Chalmers University of Technology
Co-authored papers 2
National Institutes of Health, National Cancer Institute, Center for Cancer Research
Co-authored papers 2