Author details

Full Name

Steven E Schumacher

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36697832	Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.	Nature	2023
36040167	Tangent normalization for somatic copy-number inference in cancer genome analysis.	Bioinformatics	2022
29808010	Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.	Nat Med	2018
30093730	Author Correction: Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.	Nat Med	2018
29724721	<i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma.	Cancer Res	2018
29535149	SvABA: genome-wide detection of structural variants and indels by local assembly.	Genome Res	2018
29622463	Genomic and Functional Approaches to Understanding Cancer Aneuploidy.	Cancer Cell	2018
28104717	Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.	Neuro Oncol	2017
28726821	The whole-genome landscape of medulloblastoma subtypes.	Nature	2017
28426752	Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients.	PLoS One	2017
28713588	Genomic landscape of high-grade meningiomas.	NPJ Genom Med	2017
28664899	Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.	Sci Rep	2017
28522256	Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.	Gastroenterology	2017
29263836	Erratum: Genomic landscape of high-grade meningiomas.	NPJ Genom Med	2017
27707790	Landscape of Genomic Alterations in Pituitary Adenomas.	Clin Cancer Res	2017
28038320	Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis.	Neoplasia	2017
27869828	Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias.	Nat Genet	2017
27905446	Genomic evolution and chemoresistance in germ-cell tumours.	Nature	2016
27338572	Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.	Sci Rep	2016
26829751	MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.	Nat Genet	2016
27160768	Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.	Sci Rep	2016
26546296	MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy.	Cancer Discov	2016
26536169	Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.	N Engl J Med	2016
26061751	Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.	N Engl J Med	2015
25754088	Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.	Neuro Oncol	2015
25825052	Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.	Neuro Oncol	2015
26377837	Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.	Genome Res	2015
24793136	Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins.	Nat Genet	2014
24297863	BET bromodomain inhibition of MYC-amplified medulloblastoma.	Clin Cancer Res	2014
24434212	Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy.	Cancer Cell	2014
23525077	Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.	Nat Genet	2013
23764425	Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.	Cancer Discov	2013
24071852	Pan-cancer patterns of somatic copy number alteration.	Nat Genet	2013
23393560	Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers.	PLoS One	2013
23269662	ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens.	Genome Res	2013
23633565	Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.	Proc Natl Acad Sci U S A	2013
23245941	Î²-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.	Cell	2012
22751462	Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.	Cancer Res	2012
22832581	Subgroup-specific structural variation across 1,000 medulloblastoma genomes.	Nature	2012
22722202	Sequence analysis of mutations and translocations across breast cancer subtypes.	Nature	2012
22901813	Cancer vulnerabilities unveiled by genomic loss.	Cell	2012
22037472	Genetic and functional studies implicate HIF1Î± as a 14q kidney cancer suppressor gene.	Cancer Discovery	2011
21527027	GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers.	Genome Biol	2011