Author details

Full Name

Bronwyn M Gunn

Affiliation

ORCID

Career Start Year

2008

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37061918	Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates.	Cell Rep	2023
36947596	Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers.		2023
37131834	Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system.	Res Sq	2023
37251375	Enhancing the therapeutic activity of hyperimmune IgG against chikungunya virus using FcÎ³RIIIa affinity chromatography.	Front Immunol	2023
35251051	Editorial: Antibody Therapeutics for the Treatment of Filoviral Infection.	Front Immunol	2022
36242952	Engineering the supernatural: monoclonal antibodies for challenging infectious diseases.	Current Opinion in Biotechnology	2022
36136995	An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines.	PLoS Pathogens	2022
36521442	Holding it together: Nanoparticle stabilization of LASV trimer.		2022
34481966	High seroprevalence of SARS-CoV-2 but low infection fatality ratio eight months after introduction in Nairobi, Kenya.	International Journal of Infectious Diseases	2021
34019642	Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus.	J Exp Med	2021
33852832	A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus.	Immunity	2021
34261800	Ebola vaccine-induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects.	Sci Transl Med	2021
34093585	Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors.	Frontiers in Immunology	2021
34335620	Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma.	Front Immunol	2021
33495307	Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.	Science	2021
34613865	Building a better antibody through the Fc: advances and challenges in harnessing antibody Fc effector functions for antiviral protection.	Human Vaccines and Immunotherapeutics	2021
31301137	Survivors of Ebola Virus Disease Develop Polyfunctional Antibody Responses.	J Infect Dis	2020
32023489	Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.	Immunity	2020
32320678	Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies.	Cell Host Microbe	2020
32922962	Modified vaccinia Ankara vaccine expressing Marburg virus-like particles protects guinea pigs from lethal Marburg virus infection.	npj Vaccines	2020
33236009	An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19.	bioRxiv	2020
33004861	Molecular signatures of anthroponotic cutaneous leishmaniasis in the lesions of patients infected with Leishmania tropica.	Scientific Reports	2020
30796092	Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcÎ³R interaction on monocytes.	Sci Immunol	2019
30518655	Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine.	J Virol	2019
30629918	A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.		2019
30629917	Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection.		2019
29677181	Exploiting glycan topography for computational design of Env glycoprotein antigenicity.	PLoS Comput Biol	2018
30029854	Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.	Immunity	2018
30010950	Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate.	Journal of Infectious Diseases	2018
30096313	Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.	Cell	2018
30333617	Antibody-mediated protection against Ebola virus.	Nature Immunology	2018
30138408	Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.	PLoS Pathog	2018
30092199	A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.	Cell Host Microbe	2018
29643249	Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs.	Journal of Virology	2018
29324290	Ross River virus envelope glycans contribute to disease through activation of the host complement system.	Virology	2018
29324225	The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.	Cell Host Microbe	2018
29296883	Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs.	Blood Adv	2017
27756530	Modulating Antibody Functionality in Infectious Disease and Vaccination.	Trends in Molecular Medicine	2016
27430722	Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection.	Journal of Immunology	2016
26960182	Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.	Mucosal Immunol	2016
26468533	Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses.	Journal of Virology	2016
24429363	Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection.	J Virol	2014
23487448	Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice.	J Virol	2013
22457620	Mannose binding lectin is required for alphavirus-induced arthritis/myositis.	PLoS Pathog	2012
21224040	A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence.	Am J Pathol	2011
21131014	Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model.	Virology	2011
20053873	Immunogenicity of a live recombinant Salmonella enterica serovar typhimurium vaccine expressing pspA in neonates and infant mice born from naive and immunized mothers.	Clinical and Vaccine Immunology	2010
20605977	Salmonella vaccine vectors displaying delayed antigen synthesis in vivo to enhance immunogenicity.	Infection and Immunity	2010
20308296	Fine-tuning synthesis of Yersinia pestis LcrV from runaway-like replication balanced-lethal plasmid in a Salmonella enterica serovar typhimurium vaccine induces protection against a lethal Y. pestis challenge in mice.	Infection and Immunity	2010
20370633	New technologies in using recombinant attenuated Salmonella vaccine vectors.	Critical Reviews in Immunology	2010