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Author Details
Full Name
David Botstein
Affiliation
Calico Life Sciences LLC
ORCID
Career Start Year
1968
Papers
428
H Index
158
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37235661
Global analysis of the yeast knockout phenome.
Sci Adv
2023
37235661
Global analysis of the yeast knockout phenome.
Sci Adv
2023
35119359
Novel insights from a multiomics dissection of the Hayflick limit.
Elife
2022
35119359
Novel insights from a multiomics dissection of the Hayflick limit.
Elife
2022
34096681
A genome-scale yeast library with inducible expression of individual genes.
Mol Syst Biol
2021
34096681
A genome-scale yeast library with inducible expression of individual genes.
Mol Syst Biol
2021
34668730
Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants.
Mol Biol Cell
2021
34668730
Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants.
Mol Biol Cell
2021
32470059
A tps1ο persister-like state in Saccharomyces cerevisiae is regulated by MKT1.
PLoS One
2020
32470059
A tps1ο persister-like state in Saccharomyces cerevisiae is regulated by MKT1.
PLoS One
2020
33023927
Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases.
Genetics
2020
32631951
Fully Phased Sequence of a Diploid Human Genome Determined <i>de Novo</i> from the DNA of a Single Individual.
G3 (Bethesda)
2020
32631951
Fully Phased Sequence of a Diploid Human Genome Determined <i>de Novo</i> from the DNA of a Single Individual.
G3 (Bethesda)
2020
33023927
Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases.
Genetics
2020
30834327
Minor Isozymes Tailor Yeast Metabolism to Carbon Availability.
mSystems
2019
30834327
Minor Isozymes Tailor Yeast Metabolism to Carbon Availability.
mSystems
2019
29444955
Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast.
Mol Biol Cell
2018
30240188
Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase.
ACS Chem Biol
2018
30093589
The future of humans as model organisms.
Science
2018
30421411
Simultaneous Profiling of DNA Accessibility and Gene Expression Dynamics with ATAC-Seq and RNA-Seq.
Methods Mol Biol
2018
29444955
Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast.
Mol Biol Cell
2018
30240188
Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase.
ACS Chem Biol
2018
30093589
The future of humans as model organisms.
Science
2018
30421411
Simultaneous Profiling of DNA Accessibility and Gene Expression Dynamics with ATAC-Seq and RNA-Seq.
Methods Mol Biol
2018
27077531
Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells.
J Vis Exp
2016
27077531
Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells.
J Vis Exp
2016
27789812
Systems-level analysis of mechanisms regulating yeast metabolic flux.
Science
2016
27789812
Systems-level analysis of mechanisms regulating yeast metabolic flux.
Science
2016
25918382
Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter.
Proc Natl Acad Sci U S A
2015
25918382
Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter.
Proc Natl Acad Sci U S A
2015
26038577
Extrachromosomal circular DNA is common in yeast.
Proc Natl Acad Sci U S A
2015
26281848
Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae.
Genetics
2015
26281848
Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae.
Genetics
2015
26038577
Extrachromosomal circular DNA is common in yeast.
Proc Natl Acad Sci U S A
2015
24445804
Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae.
Nucleic Acids Res
2014
24445804
Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae.
Nucleic Acids Res
2014
25215481
Lasker⿼Koshland to genetics pioneer.
Cell
2014
25215481
Lasker⿼Koshland to genetics pioneer.
Cell
2014
23135997
Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression.
Mol Biol Cell
2013
24167267
Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.
Proc Natl Acad Sci U S A
2013
23852385
A new system for comparative functional genomics of Saccharomyces yeasts.
Genetics
2013
24300440
Rapid synthesis and screening of chemically activated transcription factors with GFP-based reporters.
J Vis Exp
2013
23749449
Phylogenetic portrait of the Saccharomyces cerevisiae functional genome.
G3 (Bethesda)
2013
23793137
Visualization and analysis of mRNA molecules using fluorescence in situ hybridization in Saccharomyces cerevisiae.
J Vis Exp
2013
23873039
Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations.
Nature
2013
23275543
Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast.
Nucleic Acids Res
2013
23302932
Automating the construction of gene ontologies.
Nat Biotechnol
2013
23550140
Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case.
G3 (Bethesda)
2013
23135997
Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression.
Mol Biol Cell
2013
23171550
TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae.
Mol Biol Cell
2013
1 - 50 of 856
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Stanford University School of Medicine
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Olga G Troyanskaya
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Stanford University Medical School
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Genentech Inc.
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Stacia R Engel
Stanford University
Co-authored papers
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Eurie L Hong
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Joshua D Rabinowitz
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Rose Oughtred
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Co-authored papers
9
Midori A Harris
University of Cambridge
Co-authored papers
9
Maria C Costanzo
The Broad Institute of Harvard and MIT
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Anne-Lise B??rresen-Dale
Institute for Cancer Research, Oslo University Hospital
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