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Author Details

Bruce S Bochner
1978
262
72
PMIDPaper TitleJournal TitlePublished Year
36747749Bioactive multi-protein adsorption enables targeted mast cell nanotherapy.2023
35971862Urine eosinophil-derived neurotoxin: A potential marker of activity in select eosinophilic disorders.Allergy2023
35835621Siglecs in allergy and asthma.Molecular Aspects of Medicine2023
37928558Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells.2023
37988049Little to no mRNA for the α- or β-chains of FcεRI in human eosinophils.2023
37553068A Cell-Free Protein Synthesis Platform to Produce a Clinically Relevant Allergen Panel.ACS Synth Biol2023
37413923Siglecs as potential targets of therapy in human mast cell- and/or eosinophil-associated diseases.2023
36629456Drug delivery targets and strategies to address mast cell diseases.2023
37384412A phase II study of Bruton's tyrosine kinase inhibition for the prevention of anaphylaxis.J Clin Invest2023
37066249Bruton's tyrosine kinase inhibition for the prevention of anaphylaxis: an open-label, phase 2 trial.Res Sq2023
34996839Siglec-F Promotes IL-33-Induced Cytokine Release from Bone Marrow-Derived Eosinophils Independently of the ITIM and ITIM-like Motif Phosphorylation.Journal of Immunology2022
35406705Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells.Cells2022
35181548An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes.J Allergy Clin Immunol Pract2022
34871159COVID-19 vaccine-related presumed allergic reactions and second dose administration by using a two-step graded protocol.Allergy and Asthma Proceedings2021
33911007Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge.Journal of Immunology2021
33745886Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference.J Allergy Clin Immunol2021
33895002Rethinking neutrophils and eosinophils in chronic rhinosinusitis.Journal of Allergy and Clinical Immunology2021
34052871Eosinophils and eosinophil-associated disorders: immunological, clinical, and molecular complexity.Seminars in Immunopathology2021
33891135Lessons learned from targeting eosinophils in human disease.Seminars in Immunopathology2021
33677080Systemic mastocytosis with an associated hematologic neoplasm complicated by recurrent anaphylaxis: Prompt resolution of anaphylaxis with the addition of avapritinib.Journal of Allergy and Clinical Immunology: In Practice2021
33777047Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody.Front Immunol2021
33864696Legends of allergy and immunology: Robert P. Schleimer.Allergy: European Journal of Allergy and Clinical Immunology2021
33191674Biology and Function of Eosinophils in Chronic Rhinosinusitis With or Without Nasal Polyps.Allergy, Asthma and Immunology Research2021
34721399Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death .Frontiers in Immunology2021
32554082Prevalence and characterization of asthma in hospitalized and nonhospitalized patients with COVID-19.Journal of Allergy and Clinical Immunology2020
31965606Eosinophil and mast cell Siglecs: From biology to drug target.Journal of Leukocyte Biology2020
32134149Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.Journal of Leukocyte Biology2020
32251643Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features.Am J Pathol2020
31818982Fibrinogen Is a Specific Trigger for Cytolytic Eosinophil Degranulation.Journal of Immunology2020
32276656Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation.BMC Research Notes2020
31977298Contributions of Eosinophils to Human Health and Disease.Annu Rev Pathol2020
32484802Bruton's tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis.Journal of Clinical Investigation2020
33374255Discovery, Function, and Therapeutic Targeting of Siglec-8.Cells2020
33391286Targeting the FcεRI Pathway as a Potential Strategy to Prevent Food-Induced Anaphylaxis.Frontiers in Immunology2020
31460762A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and -F on Immune Cells.Journal of the American Chemical Society2019
31690387Workup for eosinophilia.Allergy and Asthma Proceedings2019
30543818Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies.J Allergy Clin Immunol2019
31279009Mammalian diaphanous-related formin 1 (mDia1) coordinates mast cell migration and secretion through its actin-nucleating activity.Journal of Allergy and Clinical Immunology2019
31465299Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis.JCI insight2019
29105205Enhanced antigen presenting and T cell functions during late-phase allergic responses in the lung.Clinical and Experimental Allergy2018
28734845Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells.Journal of Allergy and Clinical Immunology2018
28888781Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β-integrin-dependent function in human eosinophils.Journal of Allergy and Clinical Immunology2018
29045815Eosinophils and eosinophil-associated diseases: An update.Journal of Allergy and Clinical Immunology2018
29924315Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways.Glycobiology2018
29879704Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge.International Archives of Allergy and Immunology2018
30197068Consultation for Elevated Blood Eosinophils: Clinical Presentations, High Value Diagnostic Tests, and Treatment Options.Journal of Allergy and Clinical Immunology: In Practice2018
30577572Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.International Journal of Molecular Sciences2018
29672914Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).J Leukoc Biol2018
29659839Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency.Glycobiology2018
29656559Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease.Journal of Leukocyte Biology2018
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