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Author Details

Mathieu J F Crupi
Cancer Research Institute, Queen's University
2012
27
12
PMIDPaper TitleJournal TitlePublished Year
37425958Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics.bioRxiv2024
36674550Extracellular Vesicles and Viruses: Two Intertwined Entities.Int J Mol Sci2023
37822719A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.Mol Ther Methods Clin Dev2023
37153626Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus.Front Immunol2023
37242495Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.Pharmaceuticals (Basel)2023
37236967Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.Nat Commun2023
37100284Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.J Biol Chem2023
36969187Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy <i>via</i> lipid modulation of the tumor microenvironment.Front Immunol2023
36713447CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.Front Immunol2023
34687845Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.Mol Ther2022
35393414Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.Nat Commun2022
35526097Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.Mol Ther2022
36405739Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.Front Immunol2022
33578036Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.Mol Ther2021
37579261Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic.ACS Nanosci Au2021
33668756Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.Int J Mol Sci2021
33809836A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion.Nanomaterials (Basel)2021
32146264RET isoform-specific interaction with scaffold protein Ezrin promotes cell migration and chemotaxis in lung adenocarcinoma.Lung Cancer2020
31645646GGA3-mediated recycling of the RET receptor tyrosine kinase contributes to cell migration and invasion.Oncogene2020
32872641Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.Membranes (Basel)2020
30875126Concise Review: Targeting Cancer Stem Cells and Their Supporting Niche Using Oncolytic Viruses.Stem Cells2019
29921327Enhanced susceptibility of cancer cells to oncolytic rhabdo-virotherapy by expression of Nodamura virus protein B2 as a suppressor of RNA interference.J Immunother Cancer2018
27872141Differential roles of RET isoforms in medullary and papillary thyroid carcinomas.Endocr Relat Cancer2017
28794017Differential recruitment of E3 ubiquitin ligase complexes regulates RET isoform internalization.J Cell Sci2017
25319892Cell surface biotinylation of receptor tyrosine kinases to investigate intracellular trafficking.Methods Mol Biol2015
26304132Distinct Temporal Regulation of RET Isoform Internalization: Roles of Clathrin and AP2.Traffic2015
22875993Alternative splicing results in RET isoforms with distinct trafficking properties.Mol Biol Cell2012
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Collaborators

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Ottawa Hospital Research Institute, University of Ottawa
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The Ottawa Hospital Research Institute
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University of Ottawa Heart Institute
Co-authored papers 1
Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 1
Ottawa Hospital Research Institute
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The Ottawa Hospital/University of Ottawa
Co-authored papers 1
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
The Institute of Cancer Research
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Leeds Institute of Medical Research at St James's, University of Leeds
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University of Ottawa
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