Author details

Full Name

Donald W Bowden

Affiliation

ORCID

Career Start Year

1972

Papers

458

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37662265	WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.	medRxiv	2023
38014529	Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis.	Circ Genom Precis Med	2023
37802043	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.	Am J Hum Genet	2023
37709864	Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.	Nat Genet	2023
37558891	Methods for estimating insulin resistance from untargeted metabolomics data.		2023
37961350	A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies.	bioRxiv	2023
37770635	Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.	Nat Genet	2023
36778386	Structural variation across 138,134 samples in the TOPMed consortium.	Res Sq	2023
37005925	Metabolomic profiling of glucose homeostasis in African Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS-FS).	Metabolomics	2023
37126548	The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.	Sci Adv	2023
36747810	Structural variation across 138,134 samples in the TOPMed consortium.	bioRxiv	2023
37046083	Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.	Nature	2023
37425772	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study.	medRxiv	2023
34166655	Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy.	Am J Ophthalmol	2022
35393509	Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.	Commun Biol	2022
35513483	Author Correction: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.	Commun Biol	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
36220816	Whole genome sequence analysis of blood lipid levels in >66,000 individuals.	Nat Commun	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35927319	Rare genetic variants explain missing heritability in smoking.	Nat Hum Behav	2022
35659450	Erratum to Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. Am J Ophthalmol 2022;233:111-123.	Am J Ophthalmol	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
34563731	Metabolomic architecture of obesity implicates metabolonic lactone sulfate in cardiometabolic disease.	Mol Metab	2021
34241534	Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes.	Circ Genom Precis Med	2021
34014961	Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study.	PLoS One	2021
33856023	Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.	Hum Mol Genet	2021
33846329	Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.	Nat Commun	2021
34108472	Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.	Nat Commun	2021
33998167	Association of Visceral Adipose Tissue and Insulin Resistance with Incident Metabolic Syndrome Independent of Obesity Status: The IRAS Family Study.		2021
33713608	Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.	Am J Hum Genet	2021
31820181	Symptoms Suggestive of Gastroparesis in a Community-Based Cohort of European Americans and African Americans with Type 2 Diabetes Mellitus.	Digestive Diseases and Sciences	2020
31895990	QRS duration is associated with all-cause mortality in type 2 diabetes: The diabetes heart study.	Journal of Electrocardiology	2020
30997919	Psoas and Paraspinous Muscle Measurements on Computed Tomography Predict Mortality in European Americans with Type 2 Diabetes Mellitus.	Journal of frailty & aging,The	2019
31688885	Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.	JAMA	2019
31869403	Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.	PLoS Genet	2019
31659325	HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.	Nat Genet	2019
30352225	Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.	Ophthalmology	2019
30487263	Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.	Diabetes	2019
29361356	The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data.	Ophthalmology	2019
31133557	Plasma apoM and S1P levels are inversely associated with mortality in African Americans with type 2 diabetes mellitus.	J Lipid Res	2019
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
31118516	Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.	Nature	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
28800042	Blood pressure indices and cardiovascular disease mortality in persons with or without diabetes mellitus.	Journal of Hypertension	2018
30510157	GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.	Nat Commun	2018
29885931	Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.	Kidney Int	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018