Skip to Main Content

Author Details

Luke A Gilbert
Arc Institute
2007
58
36
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37398273Integrative identification of non-coding regulatory regions driving metastatic prostate cancer.bioRxiv2023
37609173Environmental challenge rewires functional connections among human genes.bioRxiv2023
37333273ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway.bioRxiv2023
34545248A new era in functional genomics screens.Nat Rev Genet2022
35830852A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities.Cell Chem Biol2022
36480603IFITM proteins assist cellular uptake of diverse linked chemotypes.Science2022
36576240Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.Elife2022
36069759Highly efficient generation of isogenic pluripotent stem cell models using prime editing.Elife2022
36251389The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.Cancer Res2022
35110534A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments.Nat Commun2022
34192540Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.Cell Rep2021
33545038Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.Cell2021
33838111Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.Cell2021
34663427A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy.Genome Med2021
34326322An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer.Nat Commun2021
32619469Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.Mol Cell2020
35121976Keap1ing an eye on Slc33A1.Nat Cancer2020
32041837Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance.Cancer Res2020
32848092Mapping cancer genetics at single-cell resolution.Sci Transl Med2020
30875366Cellular response to small molecules that selectively stall protein synthesis by the ribosome.PLoS Genet2019
31266829DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway.Clin Cancer Res2019
31343870A Bounty of New Challenging Targets in Oncology for Chemical Discovery.Biochemistry2019
31395745Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.Science2019
31000834Lethal clues to cancer-cell vulnerability.Nature2019
31138768KRAS<sup>G12C</sup> inhibition produces a driver-limited state revealing collateral dependencies.Sci Signal2019
29019396The Promise and Challenge of In Vivo Delivery for Genome Therapeutics.ACS Chem Biol2018
30148842A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.PLoS Biol2018
29953808Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70).J Med Chem2018
30033370Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.Cell2018
30033366Mapping the Genetic Landscape of Human Cells.Cell2018
30340047Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.Cell2018
29091290Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform.Hepatology2018
27980086CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.Science2017
28985505Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.Mol Cell2017
26971820CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Cell Stem Cell2016
27984733A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.Cell2016
27661255Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.Elife2016
27566778A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses.Genes Dev2016
27363581Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity.Nat Commun2016
27325776Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation.Proc Natl Acad Sci U S A2016
27018887Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.Nat Chem Biol2016
26988139Versatile protein tagging in cells with split fluorescent protein.Nat Commun2016
26987018Nucleosomes impede Cas9 access to DNA in vivo and in vitro.Elife2016
25533786Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.Cell2015
26080438Next-generation libraries for robust RNA interference-based genome-wide screens.Proc Natl Acad Sci U S A2015
25307933A protein-tagging system for signal amplification in gene expression and fluorescence imaging.Cell2014
25307932Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.Cell2014
23251029Defining principles of combination drug mechanisms of action.Proc Natl Acad Sci U S A2013
24360272Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.Cell2013
24136345CRISPR interference (CRISPRi) for sequence-specific control of gene expression.Nat Protoc2013
  • 1 - 50 of 58

Recommended Authors

Kyle Ford
University of California San Diego
Career Start Year 2017
Number of shared co-authors 0
Mahmoud A Bassal
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2015
Number of shared co-authors 1
Brenton Munson
University of California San Diego
Career Start Year 2014
Number of shared co-authors 0
Tuo Zhang
Weill Cornell Medical College.
Career Start Year 2013
Number of shared co-authors 1
Aviad Tsherniak
Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard
Career Start Year 2011
Number of shared co-authors 3
Rahul K Kollipara
McDermott Center for Human Growth and Development.
Career Start Year 2010
Number of shared co-authors 3
Frederick S Vizeacoumar
College of Medicine, University of Saskatchewan
Career Start Year 2010
Number of shared co-authors 1
Richard Mitter
The Francis Crick Institute
Career Start Year 2008
Number of shared co-authors 1
Ophir Shalem
Perelman School of Medicine, University of Pennsylvania
Career Start Year 2008
Number of shared co-authors 2
Branden S Moriarity
University of Minnesota
Career Start Year 2007
Number of shared co-authors 0
Shondra M Pruett-Miller
St. Jude Children's Research Hospital.
Career Start Year 2006
Number of shared co-authors 1
Raj Chari
The National Institutes of Health
Career Start Year 2006
Number of shared co-authors 0
Christopher A Bristow
The University of Texas MD Anderson Cancer Center
Career Start Year 2005
Number of shared co-authors 4
Alan S L Wong
The University of Hong Kong
Career Start Year 2005
Number of shared co-authors 1
Maciej Paszkowski-Rogacz
Faculty of Medicine and University Hospital Carl Gustav Carus
Career Start Year 2005
Number of shared co-authors 1
Traver Hart
University of Texas MD Anderson Cancer Center
Career Start Year 2004
Number of shared co-authors 0
Prashant Mali (CM4AI)
University of California San Diego
Career Start Year 2004
Number of shared co-authors 3
Jesse S Boehm
Broad Institute of Harvard and MIT
Career Start Year 2004
Number of shared co-authors 4
Stefan Kubicek
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Career Start Year 2003
Number of shared co-authors 1
Franco J Vizeacoumar
College of Medicine, University of Saskatchewan
Career Start Year 2002
Number of shared co-authors 2
Wenyan Zhong
Oncology R&D
Career Start Year 2000
Number of shared co-authors 1
Mariano J Alvarez
Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center
Career Start Year 2000
Number of shared co-authors 2
Kevin R Brown
College Street, University of Toronto
Career Start Year 2000
Number of shared co-authors 4
Jason Moffat
University of Toronto
Career Start Year 1997
Number of shared co-authors 6
David E Root
Broad Institute of Harvard and MIT
Career Start Year 1993
Number of shared co-authors 4
Glenn S Cowley
Broad Institute of Harvard and MIT
Career Start Year 1990
Number of shared co-authors 2
Frank Buchholz
University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Career Start Year 1989
Number of shared co-authors 1
Ralf Kittler
McDermott Center for Human Growth and Development.
Career Start Year 1984
Number of shared co-authors 5
David J Adams
Wellcome Sanger Institute
Career Start Year 1980
Number of shared co-authors 1
Francisca Vazquez
Broad Institute of MIT and Harvard
Career Start Year 1979
Number of shared co-authors 4

Collaborators

Jonathan S Weissman
Whitehead Institute for Biomedical Research
Co-authored papers 26
Max A Horlbeck
Broad Institute of MIT and Harvard
Co-authored papers 16
Martin Kampmann
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 10
Lei S Qi
Stanford University
Co-authored papers 9
Jacqueline E Villalta
University of California san francisco
Co-authored papers 7
Felix Y Feng
UCSF Medical Center-Mount Zion
Co-authored papers 7
Wendell A Lim
University of California san francisco
Co-authored papers 5
Jonathan Chou
University of California san francisco
Co-authored papers 5
David A Quigley
University of California-San Francisco
Co-authored papers 5
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 4
Alan Ashworth
UCSF Helen Diller Family Comprehensive Cancer Center
Co-authored papers 4
Eric J Small
University of California san francisco
Co-authored papers 4
Lawrence Fong
University of California san francisco
Co-authored papers 3
Christopher A Maher
Washington University in St Louis
Co-authored papers 3
Marc D Perry
Ontario Institute for Cancer Research
Co-authored papers 3
Michael C Bassik
Stanford University Medical Center
Co-authored papers 3
Owen N Witte
University of California los angeles
Co-authored papers 3
Amina Zoubeidi
University of British Columbia
Co-authored papers 3
Alexander W Wyatt
University of British Columbia
Co-authored papers 3
Bruce R Conklin
Gladstone Institutes
Co-authored papers 3
Kevan M Shokat
University of California San Francisco
Co-authored papers 3
Martin E Gleave
University of British Columbia
Co-authored papers 3
Kim N Chi
University of British Columbia
Co-authored papers 3
Tomasz M Beer
OHSU Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Daniel E Spratt
University Hospitals Seidman Cancer Center, Case Western Reserve University
Co-authored papers 3
Scott A Tomlins
Rogel Cancer Center, University of Michigan Medical School ann arbor
Co-authored papers 3
Paul Lloyd
Bluestar Genomics Inc.
Co-authored papers 3
Matthew B Rettig
David Geffen School of Medicine, University of California los angeles
Co-authored papers 3
Robert E Reiter
David Geffen School of Medicine at university of california los angeles
Co-authored papers 3
Thomas J George
UF Health Cancer Center
Co-authored papers 3
Release 1.2