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Author Details

Valerie M Weaver
University of California san francisco
1988
184
78
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37537499Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.Nat Biotechnol2024
38017076Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.Nat Med2024
36797475Stiff matrix induces exosome secretion to promote tumour growth.Nat Cell Biol2023
37503095Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells.bioRxiv2023
37645943The microenvironment dictates glycocalyx construction and immune surveillance.Res Sq2023
37322009A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer.Nat Commun2023
37016139Author Correction: Tissue mechanics promote IDH1-dependent HIF1α-tenascin C feedback to regulate glioblastoma aggression.Nat Cell Biol2023
37339062Correction: Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.J Exp Med2023
37261951Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung.Cell Rep2023
36587129Extracellular Matrix Glycation and Crosslinking in Mammary Tumor Progression.Methods Mol Biol2023
36919424Correction: Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer.Cancer Res2023
34974281NCI's publication affiliation conundrum: Reframing innovation to incentivize an equitable path for advocate representation.Transl Oncol2022
35678467Mechanosensitive Steroid Hormone Signaling and Cell Fate.Endocrinology2022
35392183Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression.Matrix Biol Plus2022
35618935Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity.Nat Cancer2022
35896617Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.Oncogene2022
36287913Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality.Mol Biol Cell2022
35880301ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells.EMBO J2022
34168038Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis.Genes Dev2021
33720045Leveraging microenvironmental synthetic lethalities to treat cancer.J Clin Invest2021
33545073Membrane Tension Locks In Pluripotency.Cell Stem Cell2021
33822843Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer.J Exp Med2021
33798261EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts.J Cell Biol2021
34107299Tissue mechanics in stem cell fate, development, and cancer.Dev Cell2021
34019840Adhesion-mediated mechanosignaling forces mitohormesis.Cell Metab2021
33933557Improving DCIS diagnosis and predictive outcome by applying artificial intelligence.Biochim Biophys Acta Rev Cancer2021
34009124Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree.Elife2021
32147542Fibrosis and cancer: A strained relationship.Biochim Biophys Acta Rev Cancer2020
35122050Zena Werb 1945-2020.Nat Cancer2020
31874115Don't sugarcoat it: How glycocalyx composition influences cancer progression.J Cell Biol2020
33363702Derivation of a nuclear heterogeneity image index to grade DCIS.Comput Struct Biotechnol J2020
33330449Proteoglycans as Mediators of Cancer Tissue Mechanics.Front Cell Dev Biol2020
33207224Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells.Dev Cell2020
33122428Zena Werb (1945-2020): Mourning the loss of a tissue microenvironment icon.Proc Natl Acad Sci U S A2020
32817366Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.Sci Transl Med2020
32749238Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.J Clin Invest2020
32721948Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.J Clin Invest2020
31063753The Extracellular Matrix Modulates the Metastatic Journey.Dev Cell2019
31609314Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics.J Vis Exp2019
31495781Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells.Cell Stem Cell2019
31431174Tissue mechanics, an important regulator of development and disease.Philos Trans R Soc Lond B Biol Sci2019
31511693Controlled modelling of human epiblast and amnion development using stem cells.Nature2019
29116056Excess area dependent scaling behavior of nano-sized membrane tethers.Phys Biol2018
36908331Compartment resolved proteomics reveals a dynamic matrisome in a biomechanically driven model of pancreatic ductal adenocarcinoma.J Immunol Regen Med2018
30055167Modeling Tissue Polarity in Context.J Mol Biol2018
29853174The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate.Curr Top Dev Biol2018
30202050A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.Nat Cell Biol2018
29980625Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells.J Cell Biol2018
30298816Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference.Elife2018
29606307New Horizons in Advocacy Engaged Physical Sciences and Oncology Research.Trends Cancer2018
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Collaborators

Johnathon N Lakins
University of California san francisco
Co-authored papers 32
Jonathon M Muncie
Gladstone Institutes
Co-authored papers 11
James M Barnes
Center for Bioengineering and Tissue Regeneration
Co-authored papers 9
Laralynne Przybyla
University of California san francisco
Co-authored papers 7
FuiBoon Kai
University of California San Francisco
Co-authored papers 7
Jason C Tung
University of California san francisco
Co-authored papers 6
Russell Bainer
University of California berkeley
Co-authored papers 6
Ori Maller
Department of Research and Development, Inc.
Co-authored papers 5
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers 5
Carolyn R Bertozzi
Stanford University
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Jeffrey A Nickerson
Co-authored papers 4
Eric A Collisson
University of California san francisco
Co-authored papers 4
Kevin M Tharp
University of California berkeley
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Anders I Persson
University of California san francisco
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Alexander S Barrett
University of Colorado Anschutz Medical Campus
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Ravi Radhakrishnan
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Mark A LaBarge
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Boleslaw Lach
McMaster University
Co-authored papers 3
Carolyn A Larabell
University of California San Francisco
Co-authored papers 3
Shelly Kaushik
Invictus Oncology Pvt. Ltd.
Co-authored papers 3
Jayanta Debnath
University of California San Francisco
Co-authored papers 3
Andrei Goga
University of California San Francisco
Co-authored papers 2
Andrew Dillin
Howard Hughes Medical Institute, The University of California berkeley
Co-authored papers 2
Gabriele Bergers
VIB-Center for Cancer Biology
Co-authored papers 2
Alicia L Richards
University of Wisconsin-Madison
Co-authored papers 2
Kevin W Eliceiri
University of Wisconsin-Madison
Co-authored papers 2
William A Weiss
University of California san francisco
Co-authored papers 2
Greg A Timblin
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Catherine C Park
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Release 1.2