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Author Details

David Lydall
Institute for Cell and Molecular Biosciences, Newcastle University Medical School
1986
70
32
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
31624083Checkpoint inhibition of origin firing prevents DNA topological stress.Genes Dev2019
29043649Genome-Wide Quantitative Fitness Analysis (QFA) of Yeast Cultures.Methods Mol Biol2018
30067734Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function.PLoS Genet2018
29720420The contribution of non-essential <i>Schizosaccharomyces pombe</i> genes to fitness in response to altered nutrient supply and target of rapamycin activity.Open Biol2018
29564528Cis and trans interactions between genes encoding PAF1 complex and ESCRT machinery components in yeast.Curr Genet2018
29593073Vps74 Connects the Golgi Apparatus and Telomeres in <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2018
29559500A Critical Role for Dna2 at Unwound Telomeres.Genetics2018
29145644Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA.Nucleic Acids Res2018
28546384Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast.G3 (Bethesda)2017
28754723A Functional Link Between Bir1 and the <i>Saccharomyces cerevisiae</i> Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis.G3 (Bethesda)2017
27004475Rif1 and Exo1 regulate the genomic instability following telomere losses.Aging Cell2016
27628486Costs, benefits and redundant mechanisms of adaption to chronic low-dose stress in yeast.Cell Cycle2016
27385340Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis.Mol Biol Cell2016
27134314Bayesian hierarchical modelling for inferring genetic interactions in yeast.J R Stat Soc Ser C Appl Stat2016
25925573The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks.Nucleic Acids Res2015
26297725Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae.G3 (Bethesda)2015
26264873The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases.J Mol Biol2015
26168240Quantitative Fitness Analysis Identifies exo1â¿¿ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe.PLoS One2015
24906175Fast Bayesian parameter estimation for stochastic logistic growth models.Biosystems2014
25122752The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.Nucleic Acids Res2014
24835988Interplay between nonsense-mediated mRNA decay and DNA damage response pathways reveals that Stn1 and Ten1 are the key CST telomere-cap components.Cell Rep2014
23776642Pentose phosphate pathway function affects tolerance to the G-quadruplex binder TMPyP4.PLoS One2013
23959798The yeast copper response is regulated by DNA damage.Mol Cell Biol2013
22203190Similarities and differences between "uncapped" telomeres and DNA double-strand breaks.Chromosoma2012
22941615Simple, non-radioactive measurement of single-stranded DNA at telomeric, sub-telomeric, and genomic loci in budding yeast.Methods Mol Biol2012
22941614Quantitative amplification of single-stranded DNA.Methods Mol Biol2012
22907268A quantitative fitness analysis workflow.J Vis Exp2012
21490951Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.PLoS Genet2011
22384331Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast.G3 (Bethesda)2011
21414991Customizable views on semantically integrated networks for systems biology.Bioinformatics2011
20620949Telomere replication: Mre11 leads the way.Mol Cell2010
21045806Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.EMBO J2010
20808892Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.PLoS Genet2010
20509870Colonyzer: automated quantification of micro-organism growth characteristics on solid agar.BMC Bioinformatics2010
19380905Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52.Genetics2009
19629039Taming the tiger by the tail: modulation of DNA damage responses by telomeres.EMBO J2009
18418382Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres.EMBO J2008
18828915A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection.Genome Biol2008
18756267Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response.EMBO J2008
18845848A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae.Genetics2008
17015293Modelling the checkpoint response to telomere uncapping in budding yeast.J R Soc Interface2007
17618841Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.DNA Repair (Amst)2007
16118425Pulsed-field gel electrophoresis of budding yeast chromosomes.Methods Mol Biol2006
16767084Linear chromosome maintenance in the absence of essential telomere-capping proteins.Nat Cell Biol2006
16765654MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants.DNA Repair (Amst)2006
16793407Detecting repair intermediates in vivo: effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast.Methods Enzymol2006
16564010A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.Cell2006
15970690The PAL-mechanism of chromosome maintenance: causes and consequences.Cell Cycle2005
16046284Chromatin and the DNA damage response.DNA Repair (Amst)2005
15126386EXO1 plays a role in generating type I and type II survivors in budding yeast.Genetics2004
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Collaborators

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Co-authored papers 10
Manchester Metropolitan University (MMU)
Co-authored papers 7
MedImmune Ltd.
Co-authored papers 3
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
University of California San Francisco
Co-authored papers 1
Delft University of Technology
Co-authored papers 1
Newcastle University
Co-authored papers 1
Children's Hospital Los Angeles
Co-authored papers 1
Co-authored papers 1
Brandeis University
Co-authored papers 1
Oxford e-Research Centre, University of Oxford
Co-authored papers 1
Co-authored papers 1
Boston University School of Medicine, Boston University
Co-authored papers 1
College Street, University of Toronto
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Newcastle University
Co-authored papers 1