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Author Details

Junhong Han
West China Hospital, Sichuan University
2007
28
16
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37815873Hepatitis B virus infection disrupts homologous recombination in hepatocellular carcinoma by stabilizing resection inhibitor ADRM1.J Clin Invest2023
33548228The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer.J Biol Chem2021
32296031Cancer-associated histone mutation H2BG53D disrupts DNA-histone octamer interaction and promotes oncogenic phenotypes.Signal Transduct Target Ther2020
32353513Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.J Struct Biol2020
31021318Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals.Elife2019
31098304Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 in <i>Pneumocystis carinii</i>.Signal Transduct Target Ther2019
30791110The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B.Hepatology2019
30065069Rtt105 functions as a chaperone for replication protein A to preserve genome stability.EMBO J2018
29033319Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress.Mol Cell2017
26908650A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks.Nucleic Acids Res2016
26376656Detecting the H3F3A mutant allele found in high-grade pediatric glioma by real-time PCR.J Neurooncol2016
27229140The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.Science2016
24573675The Ddc1-Mec3-Rad17 sliding clamp regulates histone-histone chaperone interactions and DNA replication-coupled nucleosome assembly in budding yeast.J Biol Chem2014
25449133Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall.Mol Cell2014
24733475Pneumocystis jirovecii Rtt109, a novel drug target for Pneumocystis pneumonia in immunosuppressed humans.Antimicrob Agents Chemother2014
23907119A lesson learned from the H3.3K27M mutation found in pediatric glioma: a new approach to the study of the function of histone modifications in vivo?Cell Cycle2013
24209620A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.Cell2013
24260132A cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylation.PLoS One2013
22228774Human histone acetyltransferase 1 protein preferentially acetylates H4 histone molecules in H3.1-H4 over H3.3-H4.J Biol Chem2012
22844255The SCFDia2 ubiquitin E3 ligase ubiquitylates Sir4 and functions in transcriptional silencing.PLoS Genet2012
20656950Pneumocystis carinii expresses an active Rtt109 histone acetyltransferase.Am J Respir Cell Mol Biol2011
20188666A role for Gcn5 in replication-coupled nucleosome assembly.Mol Cell2010
20634314Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication.Genes Dev2010
19855395Involvement of a chromatin remodeling complex in damage tolerance during DNA replication.Nat Struct Mol Biol2009
17369253The Rtt109-Vps75 histone acetyltransferase complex acetylates non-nucleosomal histone H3.J Biol Chem2007
17272723Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication.Science2007
17314980Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.Nature2007
17690098Acetylation of lysine 56 of histone H3 catalyzed by RTT109 and regulated by ASF1 is required for replisome integrity.J Biol Chem2007
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Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 1
University of California San Francisco
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Institute for Therapeutics Discovery and Development, University of Minnesota
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Mayo Clinic Arizona
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Boston University School of Medicine, Boston University
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