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Author Details

Javier G??mez
Hospital Universitario Marques de Valdecilla
2003
20
17
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36252599Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial.Lancet Respir Med2023
35012962Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.Life Sci Alliance2022
33875457Molecular diagnosis in non-small-cell lung cancer: expert opinion on <i>ALK</i> and <i>ROS1</i> testing.J Clin Pathol2022
34075384Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.medRxiv2021
32224306Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial.Lancet Oncol2020
25730906Gene expression profile predictive of response to chemotherapy in metastatic colorectal cancer.Oncotarget2015
25197016MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer.BMC Cancer2014
23117071Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy.Ann Oncol2013
23397080Trabectedin as single agent in relapsed advanced ovarian cancer: results from a retrospective pooled analysis of three phase II trials.Med Oncol2013
22484722A comprehensive safety analysis confirms rhabdomyolysis as an uncommon adverse reaction in patients treated with trabectedin.Cancer Chemother Pharmacol2012
23269338Leydig cell tumour: enucleation as a therapeutic choice in a case with atypical symptoms.Arch Esp Urol2012
20643862Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6-12 months) subpopulation of OVA-301 phase III randomized trial.Ann Oncol2011
21546066Correlation between CA-125 serum level and response by RECIST in a phase III recurrent ovarian cancer study.Gynecol Oncol2011
21416137Trabectedin has a low cardiac risk profile: a comprehensive cardiac safety analysis.Cancer Chemother Pharmacol2011
19417019Phase I and pharmacokinetic study of trabectedin as a 1- or 3-hour infusion weekly in patients with advanced solid malignancies.Clin Cancer Res2009
19652065Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.J Clin Oncol2009
18483378Phase I clinical and pharmacokinetic study of plitidepsin as a 1-hour weekly intravenous infusion in patients with advanced solid tumors.Clin Cancer Res2008
17553201Phase II study of trabectedin in pretreated patients with advanced colorectal cancer.Clin Colorectal Cancer2007
15084621Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy.J Clin Oncol2004
12932661Phase I and pharmacokinetic study of Yondelis (Ecteinascidin-743; ET-743) administered as an infusion over 1 h or 3 h every 21 days in patients with solid tumours.Eur J Cancer2003
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Collaborators

Clinical R&D
Co-authored papers 6
Promontory Therapeutics Inc.
Co-authored papers 6
Hospital Universitario 12 de Octubre
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IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
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Centro Sandoval and Hospital Universitario Clinico de San Carlos
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University College London
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University of the Basque Country UPV/EHU
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Departamento de Toxicologia y Farmacologia Preclinica
Co-authored papers 2
Clinical Development
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario HM Monteprincipe, HM Hospitales
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Clinical Development
Co-authored papers 2
University of Geneva
Co-authored papers 2
Instituto de Salud Carlos III, Hospital Universitario La Princesa
Co-authored papers 2
Campus Universidad Autonoma de Madrid
Co-authored papers 2
Hospital Germans Trias i Pujol
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Hospital Universitario Quironsalud Madrid
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Campus Universidad Autonoma de Madrid
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Hospital Universitario de Getafe
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University College London
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University of California San Francisco
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Universidad Europea
Co-authored papers 2
Hospital Universitario de La Princesa
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Hospital Universitario de Getafe
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Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
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Hospital Universitario Ramon y Cajal
Co-authored papers 2