Author details

Full Name

Shirin Arastu-Kapur

Affiliation

Stanford University School of Medicine

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
32390638	Alzheimer's Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains.	J Alzheimers Dis	2020
31999052	Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388.	Pharmacol Res Perspect	2020
30746447	<i>Porphyromonas gingivalis</i> in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.	Sci Adv	2019
31177613	Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors.	FEBS J	2019
29182146	Immunoproteasome functions explained by divergence in cleavage specificity and regulation.	Elife	2017
28435528	Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit.	ACS Med Chem Lett	2017
26924128	A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors.	Invest New Drugs	2016
27071340	Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay.	Br J Haematol	2016
25709080	Ricolinostat (ACY-1215) induced inhibition of aggresome formation accelerates carfilzomib-induced multiple myeloma cell death.	Br J Haematol	2015
24518207	A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.	Leukemia	2014
21364033	Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.	Clin Cancer Res	2011
22216088	Molecular mechanisms of bortezomib resistant adenocarcinoma cells.	PLoS One	2011
19429678	An ab Initio structural model of a nucleoside permease predicts functionally important residues.	J Biol Chem	2009
18246061	Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum.	Nat Chem Biol	2008
16607671	Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.	Chembiochem	2006
17083274	Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion.	PLoS Pathog	2006
16835460	Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii.	Eukaryot Cell	2006
16464630	Point mutations within the LdNT2 nucleoside transporter gene from Leishmania donovani confer drug resistance and transport deficiency.	Int J Biochem Cell Biol	2006
15501825	Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter.	J Biol Chem	2005
12807872	Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.	J Biol Chem	2003

1 - 20 of 20

Matthew J O'Meara

University of Michigan ann arbor

Career Start Year 2013

Number of shared co-authors 3

Dhanasekaran Shanmugam

CSIR - National Chemical Laboratory

Career Start Year 2008

Number of shared co-authors 1

David T Barkan

Novartis Institutes for BioMedical Research, Inc.

Career Start Year 2007

Number of shared co-authors 4

Priyadarshini Jaishankar

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2005

Number of shared co-authors 2

Case W McNamara

a division of The Scripps Research Institute La Jolla

Career Start Year 2004

Number of shared co-authors 1

Dhiraj Kumar

Johns Hopkins University School of Medicine

Career Start Year 2004

Number of shared co-authors 2

Paul H Davis

University of Nebraska at Omaha

Career Start Year 2003

Number of shared co-authors 1

Luke L Lairson

The Scripps Research Institute

Career Start Year 2003

Number of shared co-authors 0

Noel Southall

National Center for Advancing Translational Sciences, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 0

Craig J Thomas

Center for Cancer Research, National Cancer Institute

Career Start Year 2001

Number of shared co-authors 0

Stuart A Ralph

Bio21 Molecular Science and Biotechnology Institute, University of Melbourne

Career Start Year 2001

Number of shared co-authors 1

Jason E Gestwicki

Institute for Neurodegenerative Diseases, University of California San Francisco

Career Start Year 2000

Number of shared co-authors 7

Giselle M Knudsen

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1999

Number of shared co-authors 8

Soumya S Ray

Lysosomal Therapeutics Inc.

Career Start Year 1997

Number of shared co-authors 1

Adam R Renslo

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1997

Number of shared co-authors 4

Jack Taunton

University of California san francisco

Career Start Year 1996

Number of shared co-authors 6

Paul de Figueiredo

Texas A&M University, College Station

Career Start Year 1995

Number of shared co-authors 1

Paul J Hergenrother

University of Illinois at Urbana-Champaign

Career Start Year 1995

Number of shared co-authors 0

James C Whisstock

Monash University

Career Start Year 1994

Number of shared co-authors 3

Elizabeth A Winzeler

University of California San Diego

Career Start Year 1991

Number of shared co-authors 2

Sabine Ottilie

University of California San Diego

Career Start Year 1991

Number of shared co-authors 1

Raymond Hui

University of Toronto

Career Start Year 1991

Number of shared co-authors 1

Miha Renko

Jozef Stefan Institute

Career Start Year 1990

Number of shared co-authors 1

Andreas Hofmann

Heidelberg University

Career Start Year 1989

Number of shared co-authors 0

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 1

Frederick S Buckner

University of Washington

Career Start Year 1986

Number of shared co-authors 1

Christophe L M J Verlinde

University of Washington

Career Start Year 1984

Number of shared co-authors 1

Wesley C Van Voorhis

Center for Emerging and Re-emerging Infectious Diseases, University of Washington

Career Start Year 1982

Number of shared co-authors 2

David S Roos

University of Pennsylvania

Career Start Year 1979

Number of shared co-authors 2

James H McKerrow

Sandler Center for Drug Discovery, University of California San Francisco

Career Start Year 1970

Number of shared co-authors 5

row(s) 1 - 30 of 30

Janet L Anderl

Onyx Pharmaceuticals, Inc.

Co-authored papers 3

Debasish Raha

Co-authored papers 3

Andrew J Yee

Co-authored papers 2

Lawrence H Boise

Winship Cancer Institute, Emory University

Co-authored papers 1

Peter Leif Bergsagel

Co-authored papers 1

David S Siegel

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Florencia La Greca

Department of Pharmaceutical Chemistry , University of California san francisco

Co-authored papers 1

Jonathan J Keats

Co-authored papers 1

Gregory J Ahmann

Co-authored papers 1

Francesco Caiazza

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Anthony J O'Donoghue

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Co-authored papers 1

Kailash C Gupta

National Centre for Cell Science, SP Pune University Campus

Co-authored papers 1

Ujwal Shinde

Oregon Health & Science University

Co-authored papers 1

Christoph Driessen

Cantonal Hospital St. Gallen

Co-authored papers 1

Matthew Ravalin

Stanford University

Co-authored papers 1

Michael B Winter

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Ravi Vij

Co-authored papers 1

Piotr Mydel

Co-authored papers 1

Markus-Frederik Bohn

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 1

Sundar Jagannath

Co-authored papers 1

Charles S Craik

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Philip J Rosenthal

University of California at San Francisco

Co-authored papers 1

Peter Cimermancic

Verily Life Sciences LLC

Co-authored papers 1

Tonia J Buchholz

Onyx Pharmaceuticals, Inc.

Co-authored papers 1

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