Author details

Full Name

John A Hanover

Affiliation

ORCID

Career Start Year

1979

Papers

201

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36255737	Ancestry-specific high-risk gene variant profiling unmasks diabetes-associated genes.	Hum Mol Genet	2024
36824917	The Essential Role of O-GlcNAcylation in Hepatic Differentiation.		2023
38026167	-GlcNAcylation regulates OTX2's proteostasis.		2023
37930118	The essential role of O-GlcNAcylation in hepatic differentiation.		2023
37577573	Selective bioorthogonal probe for -glycan hybrid structures.		2023
37282749	Epigenetic Regulation of Hepatic Lipid Metabolism by DNA Methylation.		2023
34934185	Tools, tactics and objectives to interrogate cellular roles of O-GlcNAc in disease.	Nature Chemical Biology	2022
36112613	Nutrient sensing pathways regulating adult reproductive diapause in C. elegans.	PLoS ONE	2022
36111295	A nexus of lipid and Glcnac metabolism in physiology and disease.	Frontiers in Endocrinology	2022
35775080	Recent Advances in Stereoselective Chemical -Glycosylation Reactions.	Frontiers in Molecular Biosciences	2022
36092250	Generation of GLA-knockout human embryonic stem cell lines to model peripheral neuropathy in Fabry disease.	Molecular Genetics and Metabolism Reports	2022
35432339	Chronically Elevated -GlcNAcylation Limits Nitric Oxide Production and Deregulates Specific Pro-Inflammatory Cytokines.	Frontiers in Immunology	2022
35782611	Generation of an model for peripheral neuropathy in Fabry disease using CRISPR-Cas9 in the nociceptive dorsal root ganglion cell line 50B11.	Molecular Genetics and Metabolism Reports	2022
36387851	Pancreatic Î²-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasis .	Frontiers in Endocrinology	2022
36383567	O-GlcNAc transferase plays a non-catalytic role in C. elegans male fertility.	PLoS Genetics	2022
34303692	A tribute to William (Bill) B. Jakoby.	Analytical Biochemistry	2022
35320537	Evaluating the Role of Galectins in Clathrin-Independent Endocytosis.	Methods in Molecular Biology	2022
35294432	Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis.	PLoS Genetics	2022
35183508	Nutrient-responsive O-GlcNAcylation dynamically modulates the secretion of glycan-binding protein galectin 3.	Journal of Biological Chemistry	2022
35093590	Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice.	Cell Mol Gastroenterol Hepatol	2022
34764359	Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass.	Scientific Reports	2021
33902430	O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature.	Clin Proteomics	2021
33883138	Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver.	Science advances	2021
34029673	O-GlcNAc cycling mediates energy balance by regulating caloric memory.	Appetite	2021
33925313	Drosophila -GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes.	Cells	2021
33006972	The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress.	PLoS Genetics	2020
32402277	Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis.	Cell Reports	2020
33253217	Cardiomyocyte Oga haploinsufficiency increases O-GlcNAcylation but hastens ventricular dysfunction following myocardial infarction.	PLoS ONE	2020
33300544	O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.	Brain	2020
33329753	-GlcNAc: Regulator of Signaling and Epigenetics Linked to X-linked Intellectual Disability.	Frontiers in Genetics	2020
31467334	Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development.	Scientific Reports	2019
30213846	Evaluation of a PET Radioligand to Image <i>O</i>-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse.	J Nucl Med	2019
31281295	Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny's Metabolism and Microbiome.	Frontiers in Microbiology	2019
29594839	O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle.	Journal of Bioenergetics and Biomembranes	2018
29049853	Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration.	Journal of Neurochemistry	2018
30250452	Nutrient-Driven -GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution.	Frontiers in Endocrinology	2018
29954943	A genetic model to study GlcNAc cycling in immortalized mouse embryonic fibroblasts.	Journal of Biological Chemistry	2018
29904918	T cell development and the physiological role of O-GlcNAc.	FEBS Letters	2018
29176683	Coronary calcification in adults with Turner syndrome.	Genetics in Medicine	2018
28246173	Nutrient-driven -linked -acetylglucosamine (-GlcNAc) cycling impacts neurodevelopmental timing and metabolism.	Journal of Biological Chemistry	2017
28428286	A Genetic Analysis of the Detoxification Response.	Genetics	2017
28344780	Abnormal glycosylation in Joubert syndrome type 10.	Cilia	2017
28408483	-GlcNAc cycling and the regulation of nucleocytoplasmic dynamics.	Biochemical Society Transactions	2017
27856697	Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies.	G3: Genes, Genomes, Genetics	2017
28063873	Detection of phosphoglucomutase-3 deficiency by lectin-based flow cytometry.	J Allergy Clin Immunol	2017
26683465	A Short Synthetic Peptide Mimetic of Apolipoprotein A1 Mediates Cholesterol and Globotriaosylceramide Efflux from Fabry Fibroblasts.	JIMD Rep	2016
31453208	A comparison of strategies for immortalizing mouse embryonic fibroblasts.		2016
26799652	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).	Autophagy	2016
26957542	Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation.	Journal of Biological Chemistry	2016
27471012	Development of a model system for neuronal dysfunction in Fabry disease.	Mol Genet Metab	2016