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Author Details

Gottfried E Konecny
David Geffen School of Medicine at University of California Los Angeles
1984
140
52
PMIDPaper TitleJournal TitlePublished Year
36136304Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy.Clin Cancer Res2023
37716223Pathologic response to neoadjuvant chemotherapy in ovarian cancer and its association with outcome: A surrogate marker of survival.Gynecol Oncol2023
37102083Strategies for prevention and management of ocular events occurring with mirvetuximab soravtansine.Gynecol Oncol Rep2023
36709663Results of TRIO-15, a multicenter, open-label, phase II study of the efficacy and safety of ganitumab in patients with recurrent platinum-sensitive ovarian cancer.Gynecol Oncol2023
34782936MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.Virchows Arch2022
35380877The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17.Sci Signal2022
35642517Homologous recombination deficiency and molecular subtype are associated with immunogenicity in ovarian cancer.Biomark Med2022
35690498OVARIO phase II trial of combination niraparib plus bevacizumab maintenance therapy in advanced ovarian cancer following first-line platinum-based chemotherapy with bevacizumab.Gynecol Oncol2022
36075393NCCN Guidelines® Insights: Ovarian Cancer, Version 3.2022.J Natl Compr Canc Netw2022
36104728Expression of immune checkpoint regulators, programmed death-ligand 1 (PD-L1/PD-1), cytotoxic T lymphocyte antigen 4 (CTLA-4), and indolaimine-2, 3-deoxygenase (IDO) in uterine mesenchymal tumors.Diagn Pathol2022
36240472State of the Biomarker Science in Ovarian Cancer: A National Cancer Institute Clinical Trials Planning Meeting Report.JCO Precis Oncol2022
36222710Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes.Clin Cancer Res2022
34645648Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study.Clin Cancer Res2022
33229045Analysis in epithelial ovarian cancer identifies KANSL1 as a biomarker and target gene for immune response and HDAC inhibition.Gynecol Oncol2021
33545690Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2021
33537389PARPi after PARPi in epithelial ovarian cancer.Gynecol Oncol Rep2021
33667670Phase III, randomized trial of mirvetuximab soravtansine versus chemotherapy in patients with platinum-resistant ovarian cancer: primary analysis of FORWARD I.Ann Oncol2021
33752918Population exposure-efficacy and exposure-safety analyses for rucaparib in patients with recurrent ovarian carcinoma from Study 10 and ARIEL2.Gynecol Oncol2021
33608192Image-Guided Percutaneous Thermal Ablation of Oligometastatic Ovarian and Non-Ovarian Gynecologic Tumors.J Vasc Interv Radiol2021
34904811Integrated, Integral, and Exploratory Biomarkers in the Development of Poly(ADP-Ribose) Polymerase Inhibitors.Cancer J2021
34642026Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer.Gynecol Oncol2021
33941784Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2).Nat Commun2021
34036138Treatment of metastatic placental site trophoblastic tumor with surgery, chemotherapy, immunotherapy and coil embolization of multiple pulmonary arteriovenous fistulate.Gynecol Oncol Rep2021
32404957Association of PD-L1 expression by immunohistochemistry and gene microarray with molecular subtypes of ovarian tumors.Mod Pathol2020
31815769Mechanisms of PARP inhibitor resistance in ovarian cancer.Curr Opin Obstet Gynecol2020
31804230Biomarkers that may predict response to immunotherapy in ovarian malignancies.Curr Opin Obstet Gynecol2020
32554541Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).Clin Cancer Res2020
32473302Prognostic gene expression signature for high-grade serous ovarian cancer.Ann Oncol2020
30571658Editorial: The potential for precision medicine to improve care and speed the development of new treatments in breast and gynecologic malignancies.Curr Opin Obstet Gynecol2019
31257009Comprehensive genomic profiling of recurrent endometrial cancer: Implications for selection of systemic therapy.Gynecol Oncol2019
30922730Inhibition of PD-1 and VEGF in microsatellite-stable endometrial cancer.Lancet Oncol2019
30979685Combining PARP and CDK4/6 inhibitors in MYC driven ovarian cancer.EBioMedicine2019
30765787Oncogenic Y68 frame shift mutation of PTEN represents a mechanism of docetaxel resistance in endometrial cancer cell lines.Sci Rep2019
30425037BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.Cancer Discov2019
29069370Ten-year results of intense dose-dense chemotherapy show superior survival compared with a conventional schedule in high-risk primary breast cancer: final results of AGO phase III iddEPC trial.Ann Oncol2018
31799491<i>BRAF</i> Mutations Occur Infrequently in Ovarian Cancer but Suggest Responsiveness to BRAF and MEK Inhibition.JCO Precis Oncol2018
29925470Factors that influence survival in high-grade serous ovarian cancer: A complex relationship between molecular subtype, disease dissemination, and operability.Gynecol Oncol2018
29951943RNA Sequencing of Carboplatin- and Paclitaxel-Resistant Endometrial Cancer Cells Reveals New Stratification Markers and Molecular Targets for Cancer Treatment.Horm Cancer2018
30815151Developing a Clinico-Molecular Test for Individualized Treatment of Ovarian Cancer: The interplay of Precision Medicine Informatics with Clinical and Health Economics Dimensions.AMIA Annu Symp Proc2018
30485824Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines.Cell Rep2018
29227302The target invites a foe: antibody-drug conjugates in gynecologic oncology.Curr Opin Obstet Gynecol2018
27941363Cancer genomics and clinical practice: how can we close the gap more quickly?Curr Opin Obstet Gynecol2017
28380314Understanding Exceptional Responses to Poly (ADP-ribose) Polymerase Inhibition in Sporadic Ovarian Cancer.J Clin Oncol2017
28159814Bevacizumab May Differentially Improve Ovarian Cancer Outcome in Patients with Proliferative and Mesenchymal Molecular Subtypes.Clin Cancer Res2017
28964622Intraperitoneal disease dissemination patterns are associated with residual disease, extent of surgery, and molecular subtypes in advanced ovarian cancer.Gynecol Oncol2017
28916367Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial.Lancet2017
28882436Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2.Gynecol Oncol2017
27908594Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.Lancet Oncol2017
27870704Clinical Outcomes for Stereotactic Ablative Radiotherapy in Oligometastatic and Oligoprogressive Gynecological Malignancies.Int J Gynecol Cancer2017
28041631Targeting fibroblast growth factor pathways in endometrial cancer.Curr Probl Cancer2017
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Collaborators

David Geffen School of Medicine at university of california los angeles
Co-authored papers 33
University of Minnesota
Co-authored papers 27
Mayo Clinic College of Medicine
Co-authored papers 20
Otto-Friedrich-University Bamberg
Co-authored papers 18
Center for Individualized Medicine, Mayo Clinic
Co-authored papers 16
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H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 13
David Geffen School of Medicine, University of California los angeles
Co-authored papers 11
Duke School of Medicine
Co-authored papers 11
Center for Cancer Genetic Epidemiology, University of Cambridge
Co-authored papers 11
Mayo Clinic
Co-authored papers 11
School of Clinical Medicine, University of NSW Sydney, Lowy Cancer Research Centre
Co-authored papers 10
Rollins School of Public Health, Emory University
Co-authored papers 9
Mayo Clinic
Co-authored papers 9
University of Michigan School of Public Health ann arbor
Co-authored papers 9
University of Southern California
Co-authored papers 9
Cedars-Sinai Medical Center
Co-authored papers 9
Memorial Sloan-Kettering Cancer Center
Co-authored papers 9
University Claude Bernard Lyon I
Co-authored papers 9
University of Cambridge
Co-authored papers 9
Division of Clinical Trials and Biostatistics, Mayo Clinic
Co-authored papers 9
National Cancer Institute, National Institutes of Health
Co-authored papers 8
Ovarian Cancer Action Research Centre, Imperial College London
Co-authored papers 8
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 8
International Hereditary Cancer Center, Pomeranian Medical University
Co-authored papers 8
Huntsman Cancer Institute, University of Utah
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Hollings Cancer Center, Medical University of South Carolina
Co-authored papers 8
International Hereditary Cancer Center, Pomeranian Medical University
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Fred Hutchinson Cancer Research Center
Co-authored papers 7
German Cancer Research Center (DKFZ)
Co-authored papers 7