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Author Details

Assaf Alon
Harvard Medical School
2008
18
13
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35654455The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination.Genes Dev2022
34326236Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2.Science2021
33791693Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2.bioRxiv2021
34880501Structures of the Ï¿<sub>2</sub> receptor enable docking for bioactive ligand discovery.Nature2021
34824238Dormant spores sense amino acids through the B subunits of their germination receptors.Nat Commun2021
34844425The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3.mBio2021
30367560cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures.Protein Sci2019
28559337Identification of the gene that codes for the Ï¿<sub>2</sub> receptor.Proc Natl Acad Sci U S A2017
28315261Structural Perspectives on Sigma-1 Receptor Function.Adv Exp Med Biol2017
25670500AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences.Proteins2015
23704371A secreted disulfide catalyst controls extracellular matrix composition and function.Science2013
23867277An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1.J Mol Biol2013
22801504The dynamic disulphide relay of quiescin sulphydryl oxidase.Nature2012
23209798Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596.PLoS One2012
23068612Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase.FEBS Lett2012
21532589Improved molecular replacement by density- and energy-guided protein structure optimization.Nature2011
20211621QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains.FEBS Lett2010
18393449Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis.Biochemistry2008
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Collaborators

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Co-authored papers 3
University of Michigan ann arbor
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Department of Pharmaceutical Chemistry, University of California san francisco
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Novartis
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University of Washington
Co-authored papers 2
Matrahaza University and Teaching Hospital
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
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Co-authored papers 2
University of Washington
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Department of Preclinical Safety, Novartis Institutes for BioMedical Research
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Columbia University
Co-authored papers 1
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Co-authored papers 1