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Author Details

Tarik M??r??y
Institut de recherches cliniques de Montreal
1985
159
55
PMIDPaper TitleJournal TitlePublished Year
37035206The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma.Front Oncol2023
37756525Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.Blood2023
37593101Editorial: New emerging functions of transcription factors and RNA-binding proteins in the development of hematological malignancies.Front Oncol2023
36068335Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition.Oncogene2022
35453704Myc-Interacting Zinc Finger Protein 1 (Miz-1) Is Essential to Maintain Homeostasis and Immunocompetence of the B Cell Lineage.Biology (Basel)2022
35815807The X-Linked Helicase DDX3X Is Required for Lymphoid Differentiation and MYC-Driven Lymphomagenesis.Cancer Res2022
36620925DDX3: a relevant therapeutic target for lymphoma?Expert Opin Ther Targets2022
36071278Author Correction: GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors.Commun Biol2022
33460833Targeting MYC: From understanding its biology to drug discovery.Eur J Med Chem2021
34857890GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors.Commun Biol2021
34408010Severe Inflammatory Reactions in Mice Expressing a GFI1<sup>P2A</sup> Mutant Defective in Binding to the Histone Demethylase KDM1A (LSD1).J Immunol2021
33993920The transcription factors GFI1 and GFI1B as modulators of the innate and acquired immune response.Adv Immunol2021
33134177Crosstalk Between MYC and lncRNAs in Hematological Malignancies.Front Oncol2020
33193732Multifaceted Actions of GFI1 and GFI1B in Hematopoietic Stem Cell Self-Renewal and Lineage Commitment.Front Genet2020
31004086A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells.Sci Rep2019
29925903Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice.Leukemia2019
31273062Deletion of the Miz-1 POZ Domain Increases Efficacy of Cytarabine Treatment in T- and B-ALL/Lymphoma Mouse Models.Cancer Res2019
31508375Role of GFI1 in Epigenetic Regulation of MDS and AML Pathogenesis: Mechanisms and Therapeutic Implications.Front Oncol2019
30894540Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.Nat Commun2019
29651020GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.Nat Commun2018
31225488GFI1's role in DNA repair suggests implications for tumour cell response to treatment.Cell Stress2018
29674496GFI1 is required for <i>RUNX1/ETO</i> positive acute myeloid leukemia.Haematologica2018
27820734The role of the transcriptional repressor growth factor independent 1 in the formation of myeloid cells.Curr Opin Hematol2017
28082345<i>Gfi1b</i> controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes.Haematologica2017
28395797Generation and characterization of human iPSC line MML-6838-Cl2 from mobilized peripheral blood derived megakaryoblasts.Stem Cell Res2017
27080012GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome.Exp Hematol2016
26619147GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1.Nat Cell Biol2016
27271479Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells.Sci Rep2016
27467586Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1.PLoS One2016
27216773Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML.Exp Hematol2016
26847026GFI1 as a novel prognostic and therapeutic factor for AML/MDS.Leukemia2016
25993117Neural differentiation modulates the vertebrate brain specific splicing program.PLoS One2015
26447191From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation.Blood2015
24800817Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression.PLoS One2014
25468973Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombination.Proc Natl Acad Sci U S A2014
25232500The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis.Am J Blood Res2014
24837677Rhythmic U2af26 alternative splicing controls PERIOD1 stability and the circadian clock in mice.Mol Cell2014
23528269Growth factor independence 1 (Gfi1) as a regulator of p53 activity and a new therapeutical target for ALL.Oncotarget2013
24068942Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.PLoS Genet2013
23410974Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.Cancer Cell2013
22201127Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1.J Exp Med2012
23226623Growth factor independence 1 (Gfi1) regulates cell-fate decision of a bipotential granulocytic-monocytic precursor defined by expression of Gfi1 and CD48.Am J Blood Res2012
22932805The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice.Blood2012
22865857CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.J Biol Chem2012
22523384Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells.J Immunol2012
22668850GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.Blood2012
22185794Origin of the brush cell lineage in the mouse intestinal epithelium.Dev Biol2012
21258009IL-7R-dependent survival and differentiation of early T-lineage progenitors is regulated by the BTB/POZ domain transcription factor Miz-1.Blood2011
22000024The role of the transcription factor Miz-1 in lymphocyte development and lymphomagenesis-Binding Myc makes the difference.Semin Immunol2011
21841135Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint.J Immunol2011
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Collaborators

Cyrus Khandanpour
University Hospital of Muenster
Co-authored papers 23
Ulrich D??hrsen
University Hospital Essen, University of Duisburg-Essen
Co-authored papers 15
Bert A van der Reijden
Co-authored papers 6
Joop H Jansen
Co-authored papers 5
Fran??ois Robert
Institut de recherches cliniques de Montreal
Co-authored papers 4
Berthold Göttgens
Co-authored papers 4
Bernhard Horsthemke
Co-authored papers 3
Michael Heuser
Hannover Medical School
Co-authored papers 3
Yahya Al-Matary
University Hospital Essen.
Co-authored papers 3
Arnaud Droit
Centre de Recherche du CHU de Quebec-Universite, Universite Laval
Co-authored papers 3
Daria Frank
University Hospital Muenster
Co-authored papers 2
Bertram Opalka
University Hospital Essen.
Co-authored papers 2
Kari Alitalo
Wihuri Research Institute
Co-authored papers 2
Marie-Jos??e H??bert
Universite de Montreal
Co-authored papers 2
Bartlomiej Przychodzen
Vanda Pharmaceuticals Inc.
Co-authored papers 2
Ronna Hertzano
University of Maryland School of Medicine
Co-authored papers 2
Christoph Klein
Kinderklinik und Kinderpoliklinik der Ludwig-Maximilians-Universitat Munchen
Co-authored papers 1
Roland Rad
Technical University of Munich
Co-authored papers 1
Ashok Kumar Jayavelu
German Cancer Research Center (DKFZ)
Co-authored papers 1
Gabriele H??lzl-Wenig
Universitat Heidelberg
Co-authored papers 1
Ulf Dittmer
University Hospital Essen, University of Duisburg-Essen, Institute for Virology
Co-authored papers 1
Julian Varghese
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Stefan Hutter
University Hospital
Co-authored papers 1
Doris Steinemann
Hannover Medical School
Co-authored papers 1
J??rgen Klingauf
University of Munster
Co-authored papers 1
Lianghao Mao
German Cancer Research Center (DKFZ)
Co-authored papers 1
Dong-Er Zhang
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Hauke Busch
Co-authored papers 1
Gudrun G??hring
Hannover Medical School
Co-authored papers 1
Georg Lenz
University Hospital of Muenster
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Release 1.2